{"id":10502,"date":"2020-05-28T11:57:58","date_gmt":"2020-05-28T02:57:58","guid":{"rendered":"http:\/\/aihara.la.coocan.jp\/?p=10502"},"modified":"2020-05-29T15:49:46","modified_gmt":"2020-05-29T06:49:46","slug":"%e3%82%a2%e3%83%93%e3%82%ac%e3%83%b3%e3%81%ae%e3%83%96%e3%83%ad%e3%82%b0%e8%a8%98%e4%ba%8b%e3%81%ab%e9%96%a2%e3%81%99%e3%82%8b%e3%82%b3%e3%83%a1%e3%83%b3%e3%83%88%e3%81%b8%e3%81%ae%e8%bf%94%e7%ad%94","status":"publish","type":"post","link":"http:\/\/aihara.la.coocan.jp\/?p=10502","title":{"rendered":"\u30a2\u30d3\u30ac\u30f3\u306e\u30d6\u30ed\u30b0\u8a18\u4e8b\u306b\u95a2\u3059\u308b\u30b3\u30e1\u30f3\u30c8\u3078\u306e\u8fd4\u7b54"},"content":{"rendered":"

\u30a2\u30d3\u30ac\u30f3\u3092COVID-19\u6cbb\u7642\u306b\u4f7f\u7528\u3059\u3079\u304d\u304b\uff1a\uff08\uff12\uff09\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u78ba\u5b9f\u6027\u306f\u300clow\u300d<\/b>\u306e\u8a18\u4e8b\u306b\u95a2\u3057\u3066\u3001\u53cb\u4eba\u306e\u6e6f\u6d45\u5148\u751f\uff08\u8c4a\u6a4b\u533b\u7642\u30bb\u30f3\u30bf\u30fc\u6b6f\u79d1\u53e3\u8154\u5916\u79d1\uff09\u304b\u3089\u30b3\u30e1\u30f3\u30c8\u3092\u3044\u305f\u3060\u3044\u305f\u306e\u3067\u3001\u5224\u65ad\u30d7\u30ed\u30bb\u30b9\u306b\u95a2\u3057\u3066\u3001GRADE\u3092\u4f7f\u304a\u3046\u3068\u3057\u3066\u3044\u308b\u4ed6\u306e\u65b9\u3005\u306b\u3082\u53c2\u8003\u306b\u306a\u308b\u3068\u601d\u3044\u307e\u3059\u306e\u3067\u3001\u7d39\u4ecb\u3057\u307e\u3059\u3002<\/p>\n

\u25c6\u30d6\u30ed\u30b0\u8a18\u4e8b\uff1ahttp:\/\/aihara.la.coocan.jp\/?p=10371<\/b><\/a><\/p>\n

<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
\n

\u6e6f\u6d45\u5148\u751f\uff1a
\n(1)\u30a8\u30d3\u30c7\u30f3\u30b9\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u3067\u3001\u4e0d\u7cbe\u78ba\u6027\u3067\u3059\u304c\u3001Clinical recovery\u306e\u30a2\u30a6\u30c8\u30ab\u30e0\u3067\u3001\u6df1\u523b\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002
\nd. 95%CI includes both no effect and appreciable important benefit\u3000\u3068\u3042\u308a\u307e\u3057\u305f\u3002
\n\u3044\u307e\u3060\u306b\u3001\u3053\u306e\u4e0d\u7cbe\u78ba\u6027\u3067\u3001\u6df1\u523b\u3068\u975e\u5e38\u306b\u6df1\u523b\u306e\u8a55\u4fa1\u304c\u5206\u304b\u3063\u3066\u306a\u3044\u306e\u3067\u3059\u304c\u3001\u5148\u751f\u306e\u4eca\u56de\u306e\u5224\u65ad\u3067\u306f\u3001\u4eca\u56de\u306f\u975e\u5e38\u306b\u6df1\u523b\u3067\u306a\u304f\u3001\u6df1\u523b\u3068\u3044\u3046\u3053\u3068\u306a\u306e\u3067\u3059\u3088\u306d\u3002
\n95%CI\u4e0b\u9650\u3000RR 0.68 124 fewer per 1,000\u3000\u306a\u3089\u3001\u304b\u306a\u308a\u60aa\u3044\u3088\u3046\u306a\u6c17\u3082\u3057\u305f\u306e\u3067\u3001\u6c17\u306b\u306a\u308a\u307e\u3057\u305f\u3002<\/b>\n<\/td>\n<\/tr>\n

\n

[\u76f8\u539f]
\n\u306f\u3044\u3001\u3053\u308c\u306f\u660e\u3089\u304b\u306b\u30011\u6bb5\u968e\u30b0\u30ec\u30fc\u30c9\u30c0\u30a6\u30f3\u3067\u30012\u6bb5\u968e\uff08-2\uff09\u3067\u306f\u306a\u3044\u3067\u3059\u3002
\n\u7406\u7531\u306f\u4ee5\u4e0b\u3067\u3059\u3002<\/p>\n

1. \u52b9\u679c\u63a8\u5b9a\u5024\u304cimprecision\u3068\u306a\u3063\u3066\u3044\u308b\u539f\u56e0\u306e\u6700\u5927\u7406\u7531\u306f\u3001\u304a\u305d\u3089\u304fserious RoB\u3067\u3059\u3002
\n2.\u3064\u307e\u308a\u3001RoB\u3067(-1)\u3068\u3057\u3066\u3001\u3055\u3089\u306bimprecision(-2)\u3068\u3059\u308b\u3068\u3001”very low”(*)\u3068\u306a\u3063\u3066\u3057\u307e\u3044\u307e\u3059\u3002
\n3.\u3053\u308c\u306fCoE\u306e\u91cd\u8907\u30ab\u30a6\u30f3\u30c8\u306e\u53ef\u80fd\u6027\u304c\u9ad8\u3044\u3067\u3059\u3002<\/p>\n

(*)Very low\u306e\u610f\u5473=GRADE\/DECIDE:
\n\u25cf\u300c\u52b9\u679c\u63a8\u5b9a\u5024\u306b\u5bfe\u3057\u3001\u307b\u3068\u3093\u3069\u78ba\u4fe1\u304c\u3082\u3066\u306a\u3044\u3002\u771f\u306e\u52b9\u679c\u306f\u3001\u52b9\u679c\u63a8\u5b9a\u5024\u3068\u306f\u5927\u304d\u304f\u7570\u306a\u308b\u3082\u306e\u3068\u8003\u3048\u3089\u308c\u308b\u3002\u300d
\n\u25cf\u300c\u3053\u306e\u7814\u7a76\u306f\uff0c\u8003\u3048\u3089\u308c\u308b\u52b9\u679c\u306b\u3064\u3044\u3066\u4fe1\u983c\u306e\u304a\u3051\u308b\u6307\u6a19\u3092\u63d0\u793a\u3057\u3066\u3044\u306a\u3044\u3002\u5b9f\u969b\u306e\u52b9\u679c\u306b\u5927\u304d\u306a\u76f8\u9055\uff08\u6c7a\u65ad\u3092\u5de6\u53f3\u3059\u308b\u307b\u3069\u306e\u5927\u304d\u306a\u76f8\u9055\uff09\u304c\u307f\u3068\u3081\u3089\u308c\u308b\u53ef\u80fd\u6027\u306f\u304d\u308f\u3081\u3066\u9ad8\u3044\u3002\u300d<\/p>\n

\u3053\u306e\u3088\u3046\u306a\u30ab\u30c6\u30b4\u30ea\u306b\u306f\u601d\u3048\u307e\u305b\u3093\u3057\u3001\u5b9f\u969b\u3001GRADE Working Group\u306f\u3001\u300c\u7279\u306b\u3001RoB, inconsistency, imprecision\u306b\u304a\u3044\u3066\u91cd\u8907\u30ab\u30a6\u30f3\u30c8\u306b\u3088\u308b\u7b49\u7d1a\u30c0\u30a6\u30f3\u306b\u6ce8\u610f\u3059\u3079\u3057\u300d\u3068\u767a\u8868\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u306a\u306e\u3067\u3001\u79c1\u306f\u3001RoB + imprecision\u3067(-2)\u3068\u3057\u307e\u3057\u305f\u3002
\n\u305f\u3060\u3001\u8907\u6570\u306e\u30d1\u30cd\u30eb\u30e1\u30f3\u30d0\u30fc\u306b\u3088\u308b\u7dcf\u5408\u5224\u65ad\u3068\u3057\u3066\u30013\u6bb5\u968e\u6295\u7403\u30c0\u30a6\u30f3(-3)\u3068\u3059\u308b\u5834\u5408\u3082\u3042\u308b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u30fb\u30fb\u30fb\u30fb\u3067\u3082\u305d\u306e\u5834\u5408\u306b\u306f\u3001\u305d\u308c\u306a\u308a\u306e\u8ad6\u62e0\u3092\u63d0\u793a\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002\n<\/td>\n<\/tr>\n

\n

\u6e6f\u6d45\u5148\u751f\uff1a
\n(2) ETD\u3067\u3001Balance of effects\u304c\u3001benefits>>harm\u3000\u3068\u3055\u308c\u3066\u3044\u307e\u3057\u305f\u304c\u3001\u305d\u3093\u306a\u3082\u306e\u306a\u306e\u3067\u3059\u306d\u3002
\n\u52b9\u679c\u306e\u5927\u304d\u3055\u304c\u300191 more\/1,000 (from 124 fewer to 314 more)\u306a\u306e\u3067\u3001\u70b9\u63a8\u5b9a\u5024\u306f\u3001\u52dd\u3063\u3066\u3044\u307e\u3059\u3057\u300191\u3068\u3044\u3046\u6570\u5b57\u304c\u3001\u5229\u76ca\u306f\u5927\u304d\u3044\u3068\u3082\u601d\u3044\u307e\u3057\u305f\u304c\u3001\u3042\u304f\u307e\u3067\u3082\u70b9\u63a8\u5b9a\u5024\u306a\u306e\u3067\u3001benefits>>harm\u3000\u3068\u307e\u3067\u8a00\u3048\u306a\u3044\u306e\u3067\u306f\u306a\u3044\u304b\u3068\u601d\u3044\u307e\u3057\u305f\u3002benefits>harm\u3000\u3050\u3089\u3044\u3002\u3068\u8a00\u3063\u3066\u3082\u3001\u78ba\u304b\u306b\u3001\u5148\u751f\u306e\u89e3\u8aac\u306f\u7406\u89e3\u3067\u304d\u307e\u3057\u305f\u3057\u3001\u305d\u3046\u89e3\u91c8\u3082\u3067\u304d\u308b\u3068\u601d\u3044\u307e\u3057\u305f\u3002<\/b><\/p>\n

<\/td>\n<\/tr>\n

\n

[\u76f8\u539f]
\n\u5358\u306b\u3001\u70b9\u63a8\u5b9a\u5024\u3084\u4fe1\u983c\u533a\u9593\u3092\u8003\u3048\u308b\u3068\u6e6f\u6d45\u5148\u751f\u306e\u610f\u898b\u3082\u3042\u308a\u5f97\u308b\u3068\u601d\u3044\u307e\u3059\u3002
\n\u3057\u304b\u3057\u3001\u3053\u306e\u63a8\u5968\u306b\u304a\u3044\u3066\u3001GRADE\u306e\u30b3\u30f3\u30c6\u30ad\u30b9\u30c8\u5316\u30a2\u30d7\u30ed\u30fc\u30c1\u3092\u9069\u7528\u3059\u308b\u3068\u30fb\u30fb\u30fb\u3000benefits>>>harm\u3000\u3067\u3059\u3002<\/p>\n

\u5b9f\u969b\u3001COVID-19\u80ba\u708e\u60a3\u8005\u306b\u304a\u3044\u3066\u3001\u80ba\u708e\u56de\u5fa9\u3084\u89e3\u71b1\u3068\u3044\u3046\u6709\u76ca\u30a2\u30a6\u30c8\u30ab\u30e0\u3068\u9ad8\u5c3f\u9178\u8840\u75c7\u306e\u6709\u5bb3\u30a2\u30a6\u30c8\u30ab\u30e0\u306e\u52b9\u7528\u5024\u3092\u60f3\u5b9a\u3059\u308b\u3068\u3001\u660e\u3089\u304b\u306bbenefits>>>>>>harm\u3067\u3059\u3002<\/p>\n

\u307e\u3042\u3001\u3053\u308c\u3082\u30d1\u30cd\u30eb\u306e\u8003\u3048\u65b9\u6b21\u7b2c\u306a\u308f\u3051\u3067\u3059\u304c\u3001\u4f8b\u3048\u3070\u3001\u53cc\u65b9\u306e\u30a2\u30a6\u30c8\u30ab\u30e0\u306e\u52b9\u7528\u5024\u3092\u8003\u3048\u308b\u3068\u3001
\n\u304a\u305d\u3089\u304f 95\uff08\u80ba\u708e\u56de\u5fa9\uff09 vs 5\uff08\u9ad8\u5c3f\u9178\u8840\u75c7\uff09\u306e\u3088\u3046\u306a\u3082\u306e\u3067\u306f\u306a\u3044\u3067\u3057\u3087\u3046\u304b\uff1f\u3000
\n\u3064\u307e\u308a\u3001\u81e8\u5e8a\u6539\u5584\u30a2\u30a6\u30c8\u30ab\u30e0\u306f\u6709\u5bb3\u30a2\u30a6\u30c8\u30ab\u30e0\u306e\u304a\u3088\u305d20\u500d\u306e\u4fa1\u5024\u89b3\u3067\u3059\u3002<\/p>\n

\u3061\u306a\u307f\u306b\u3001\u30a2\u30d3\u30ac\u30f3\u306e\u5bb3\u306b\u95a2\u3057\u3066\u306f\u3001\u5225\u306e\u89b3\u5bdf\u7814\u7a76<\/a>\uff082\u500d\u91cf\u4f7f\u7528\uff09\u306b\u304a\u3044\u3066\u6709\u5bb3\u30a4\u30d9\u30f3\u30c8\u306f\u307f\u3089\u308c\u3066\u3044\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/p>\n<\/td>\n<\/tr>\n

\n

\u6e6f\u6d45\u5148\u751f\uff1a
\n(3)\u5148\u751f\u306e\u5bb3\u306b\u5bfe\u3059\u308b\u89e3\u8aac\u3082\u305d\u306e\u901a\u308a\u3068\u601d\u3044\u307e\u3057\u305f\u304c\u3001\u305f\u3068\u3048\u3070\u3001\u30d1\u30cd\u30eb\u4f1a\u8b70\u3067\u3001\u3053\u306e\u8cc7\u6599\u3092\u3060\u3057\u305f\u3068\u304d\u3001\u300c\u5bb3\u304c\u5c11\u306a\u3044\u3053\u3068\u3082\u5206\u304b\u3063\u305f\u3001\u3067\u3082\u3001\u78ba\u5b9f\u6027\u306f\u975e\u5e38\u306b\u4f4e\u3067\u306a\u304f\u3001\u4f4e\u3067\u3042\u308b\u304c\u3001\u4fe1\u983c\u533a\u9593\u3082\u3001124 fewer to 314 more\u3068\u5e83\u3044\u3057\u3001\u70b9\u63a8\u5b9a\u5024\u3067\u52dd\u3063\u3066\u3044\u3066\u3082\u3001\u30a8\u30d3\u30c7\u30f3\u30b9\u3068\u3057\u3066\u81e8\u5e8a\u5224\u65ad\u3067\u304d\u308b\u3082\u306e\u3067\u3082\u306a\u3044\u306e\u3067\u3001\u4eca\u56de\u306f\u3001\u63a8\u5968\u5ea6\u306e\u6c7a\u5b9a\u306f\u3067\u304d\u306a\u3044\u3002\u300d\u3068\u3044\u3046\u30d1\u30cd\u30ea\u30b9\u30c8\u304c\u3044\u3066\u3082\u3001\u304a\u304b\u3057\u304f\u306f\u306a\u3044\u3068\u3044\u3046\u3053\u3068\u3067\u826f\u3044\u3067\u3057\u3087\u3046\u304b\u3002\n<\/td>\n<\/tr>\n

\n

[\u76f8\u539f]
\n\u201d\u7cfb\u7d71\u7684\u30ec\u30d3\u30e5\u30fc\u306e\u8457\u8005\u201d\u306a\u3089\u3070\u3001\u300c\u52b9\u679c\u306f\u306f\u3063\u304d\u308a\u3057\u306a\u3044\u300d\u3068\u5224\u65ad\u3059\u308b\u3053\u3068\u306f\u554f\u984c\u306a\u3044\u3068\u601d\u3044\u307e\u3059\u3002
\n\u3067\u3082\u3001\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u306b\u304a\u3044\u3066\u63a8\u5968\u3092\u4f5c\u6210\u3059\u308b\u5834\u5408\u306f\u305d\u3046\u306f\u3044\u304d\u307e\u305b\u3093\u3002<\/p>\n

COVID-19\u6cbb\u7642\u306e\u6700\u524d\u7dda\u3067\u8a3a\u7642\u3057\u3066\u3044\u308b\u533b\u5e2b\u3084\u60a3\u8005\u3092\u542b\u3081\u305f\u5229\u5bb3\u95a2\u4fc2\u8005\u306b\u3068\u3063\u3066\u306f\u3001\u5229\u76ca\u3068\u5bb3\u306e\u30d0\u30e9\u30f3\u30b9\u5224\u65ad\u306b\u3088\u308b\u300cDo no net harm\u300d\u3068\u3044\u3046\u539f\u5247\u3067\u3001\u610f\u601d\u6c7a\u5b9a\u3084\u884c\u52d5\u306b\u3064\u306a\u304c\u308b\u306a\u3093\u3089\u304b\u306e\u30ac\u30a4\u30c0\u30f3\u30b9\u3092\u63d0\u793a\u3059\u308b\u5fc5\u8981\u304c\u3042\u308b\u3068\u601d\u3044\u307e\u3059\u3002<\/p>\n

\u308f\u305a\u304b\u306abeneficial effect\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u304c\u3001\u201d\u6700\u3082\u3042\u308a\u3048\u308b\u52b9\u679c\u201d<\/b>\u304c\u3001\u81e8\u5e8a\u6539\u5584\u3068\u3057\u306691\/1000\u306a\u3089\u3070\u3001\u305d\u308c\u306f\u300cdo it\u300d\u306e\u201d\u65b9\u5411\u201d\u3067\u3042\u308b\u3079\u304d\u3068\u601d\u3044\u307e\u3059\u3002<\/p>\n

\u4e0a\u8a18\u306e\u4fe1\u983c\u533a\u9593\u306e124 fewer\/1000\u306f\u3001\u201d\u53ef\u80fd\u6027\u3068\u3057\u3066\u306f\u975e\u5e38\u306b\u4f4e\u3044\u304c\u30011\u9031\u9593\u306e\u5f53\u8a72\u6cbb\u7642\u306b\u304a\u3044\u3066\u81e8\u5e8a\u56de\u5fa9\u304c\u306a\u3044\u306e\u304c124\/1000\u201d<\/b>\u3068\u3044\u3046\u610f\u5473\u3067\u3059\u3002
\n\u3055\u3089\u306b\u3001\u30a2\u30a6\u30c8\u30ab\u30e0\u306e\u4fa1\u5024\u89b3\u3092\u8003\u616e\u3059\u308b\u3068\u3001\u5229\u76ca>>>\u5bb3\u306f\u660e\u767d\u3067\u3059\u3002<\/p>\n

\u3082\u3057\u3001\u70b9\u63a8\u5b9a\u5024\u304c\u30002\/1000\u3068\u3044\u3046\u4e9b\u7d30\u306a\u3082\u306e\u306a\u3089\u3070\u3001\u300cconditional rec\/intervention or comparator\u300d\u3068\u306a\u308b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002<\/p>\n

\u306a\u306e\u3067\u3001\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u30d1\u30cd\u30eb\u306f\u3001\uff08\u8a2d\u5b9a\u3057\u305f\u95be\u5024\u3092\u4f7f\u3063\u3066\uff09\u300c\u63a8\u5968\u306e\u65b9\u5411\u3068\u7a0b\u5ea6\u300d\u3092\u63d0\u793a\u3059\u3079\u304d\u3067\u3059\u3002
\n\u3053\u306e\u95be\u5024\u8a2d\u5b9a\u306b\u3001\u30a2\u30a6\u30c8\u30ab\u30e0\u306e\u76f8\u5bfe\u7684\u4fa1\u5024\u89b3\u304c\u5fc5\u8981\u3068\u306a\u3063\u3066\u304d\u307e\u3059\u3002<\/p>\n

\u300c\u63a8\u5968\u5ea6\u306e\u6c7a\u5b9a\u306f\u3067\u304d\u306a\u3044\u300d\u3068\u3044\u3046\u3053\u3068\u306f\u4e0d\u9069\u5207\u3067\u3042\u308a\u3001\u300cCOVID-19\u80ba\u708e\uff08\u4e2d\u7b49\u75c7\uff09\u60a3\u8005\u306b\u304a\u3044\u3066\u3001\u30a2\u30d3\u30ac\u30f3\u4ecb\u51651\u9031\u9593\u5f8c\u306e\u8a55\u4fa1\u3067\u52b9\u679c\u304c\u5f97\u3089\u308c\u306a\u3044\u306a\u3089\u3070\u3001\u4ed6\u306e\u6cbb\u7642\u9078\u629e\u80a2\u3092\u8003\u3048\u308b\u300d<\/b>\u3068\u3044\u3046\u306e\u304c\u73fe\u5b9f\u7684\u306a\u63a8\u5968\u6ce8\u8a18\u3067\u3059\u3002<\/p>\n<\/td>\n<\/tr>\n

\n

\u6e6f\u6d45\u5148\u751f\uff1a
\n(4)\u3082\u3057\u3001\u3053\u3093\u306a\u30d1\u30cd\u30ea\u30b9\u30c8\u304c\u3044\u3066\u306f\u304a\u304b\u3057\u3044\u3068\u306a\u308b\u3068\u3001\u30d1\u30cd\u30ea\u30b9\u30c8\u306e\u9078\u5b9a\u305d\u306e\u3082\u306e\u3092\u5909\u66f4\u3001\u307e\u305f\u306f\u3001\u30d1\u30cd\u30ea\u30b9\u30c8\u306b\u3001\u3069\u3046\u306b\u304b\u306b\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u5229\u7528\u65b9\u6cd5\u3092\u8aac\u660e\u3057\u3066\u7406\u89e3\u3057\u3066\u3082\u3089\u3046\u5fc5\u8981\u304c\u3042\u308b\u304b\u3082\u3057\u308c\u306a\u3044\u3068\u601d\u3063\u3066\u6c17\u306b\u306a\u3063\u305f\u6b21\u7b2c\u3067\u3059\u3002<\/b>\n<\/td>\n<\/tr>\n

\n

[\u76f8\u539f]
\n\u5f8c\u8005\u306e\u9078\u629e\u80a2\u3068\u601d\u3044\u307e\u3059\u3002
\n\u304a\u304b\u3057\u3044\u3068\u307e\u3067\u306f\u8a00\u3044\u307e\u305b\u3093\u304c\u3001GRADE\u306b\u3088\u308bEvidence-to-Decision\u306e\u539f\u5247\u3092\u7406\u89e3\u3057\u3066\u307b\u3057\u3044\u3068\u8003\u3048\u307e\u3059\u3002<\/p>\n

\u305d\u306e\u3088\u3046\u306a\u30d1\u30cd\u30eb\u304c\u3044\u308b\u3068\u3059\u308c\u3070\u3001(1)\u6700\u65b0GRADE\u306e\u57fa\u672c\u3092\u7406\u89e3\u3057\u3066\u3044\u306a\u3044\u3001 (2)\u63a8\u5968\u306e\u201d\u95be\u5024\u201d\u3092\u660e\u78ba\u306b\u3057\u3066\u3044\u306a\u3044\u3001(3)\u30a2\u30a6\u30c8\u30ab\u30e0\u306e\u76f8\u5bfe\u7684\u91cd\u8981\u6027\u3092\u4e8b\u524d\u6c7a\u5b9a\u3057\u3066\u3044\u306a\u3044\u3001(4)\u7d71\u8a08\u7684\u6709\u610f\u5dee\u3092\u3082\u3063\u3066\u63a8\u5968\u306e\u5f37\u3055\u3092\u6c7a\u5b9a\u3059\u308b\u3068\u52d8\u9055\u3044\u3057\u3066\u3044\u308b\u3001(5)\u60a3\u8005\u306e\u6cbb\u7642\u5bfe\u8c61\u30ab\u30c6\u30b4\u30ea\u3084\u4ecb\u5165\u671f\u9593\u306a\u3069\u30a8\u30d3\u30c7\u30f3\u30b9\u8aa4\u89e3\u3057\u3066\u3044\u308b\u3001\u306a\u3069\u304c\u63a8\u5b9a\u3055\u308c\u308b\u3068\u3001\u79c1\u306f\u601d\u3044\u307e\u3059\u3002<\/p>\n

\u30cd\u30c3\u30c8\u4e0a\u3067\u306f\u3001\u300c\u30a2\u30d3\u30ac\u30f3\u3092\u30b3\u30ed\u30ca\u611f\u67d3\u8005\u306e\u65e9\u671f\u304b\u3089\u6295\u4e0e\u3059\u3079\u304d\u300d\u3068\u3044\u3046\u3088\u3046\u306a\u610f\u898b\u3082\u3042\u308a\u307e\u3059\u304c\u3001\u305d\u3046\u3067\u306f\u306a\u3044\u3067\u3059\u3002
\n\u30d6\u30ed\u30b0\u8a18\u4e8b\u3067\u7d39\u4ecb\u3057\u305f\u30a8\u30d3\u30c7\u30f3\u30b9\u304b\u3089\u306f\u3001\u4ee5\u4e0b\u306e\u63a8\u5968\u6587\u8a00\u3068\u306a\u308b\u3068\u601d\u3044\u307e\u3059\u3002<\/p>\n

18\u6b73\u4ee5\u4e0a\u306eCOVID-19\u80ba\u708e\u60a3\u8005\u3067\u3001\uff08\u8efd\u75c7\u3001\u91cd\u75c7\u3001\u91cd\u7be4\u4f8b\u3067\u306f\u306a\u304f\uff09\u4e2d\u7b49\u75c7\u30b1\u30fc\u30b9\u306b\u5bfe\u3057\u3066\u3001\u30a2\u30d3\u30ac\u30f3\u6cbb\u7642\u30921\u9031\u9593\u5b9f\u65bd\u3059\u308b\u3000[GRADE2C]\u3002
\n\u6ce8\uff1aPCR\u967d\u6027\u3067\u3082\u75c7\u72b6\u304c\u8efd\u304f\u753b\u50cf\u691c\u67fb\u3067\u80ba\u708e\u304c\u306a\u3044\u611f\u67d3\u8005\u306f\u5bfe\u8c61\u3068\u3057\u306a\u3044\u3002\u91cd\u75c7\u30fb\u91cd\u7be4\u60a3\u8005\u3082\u5bfe\u8c61\u3068\u3057\u306a\u3044\u3002<\/b><\/span>\n<\/td>\n<\/tr>\n

\n

\u6e6f\u6d45\u5148\u751f\uff1a
\n(5)\u3053\u308c\u307e\u3067\u3001Minds\u3067\u306e\u8b1b\u7fd2\u3082\u542b\u3081\u3066\u3001\u591a\u304f\u306e\u5148\u751f\u3068\u8a71\u3042\u3063\u3066\u304d\u307e\u3057\u305f\u304c\u3001\u65e5\u672c\u306e\u533b\u5e2b\u3067\u3001\u304b\u306a\u308a\u8ad6\u6587\u304c\u8aad\u3081\u3001\u307e\u305f\u306f\u3001\u539f\u8457\u306e\u82f1\u8a9e\u8ad6\u6587\u304c\u8907\u6570\u3042\u308b\u5148\u751f\u3067\u30011000\u4eba\u4e2d999\u540d\u304c\u3001\u63a8\u5968\u7121\u3057\u3068\u5224\u65ad\u3059\u308b\u3068\u601d\u3046\u306e\u3067\u3059\u306d\u3002\u3053\u308c\u306f\u3001\u826f\u3044\u60aa\u3044\u3068\u304b\u3001\u95a2\u4fc2\u306a\u304f\u3001\u307e\u305f\u7406\u5c48\u3067\u3082\u306a\u304f\u3001\u3053\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u3067\u3001\u5f31\u3044\u884c\u306a\u3046\u3053\u3068\u3092\u63a8\u5968\u3059\u308b\u3001\u3068\u3044\u3046\u306e\u306b\u8cdb\u6210\u3067\u304d\u306a\u3044\u65b9\u304c\u307b\u3068\u3093\u3069\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u3002\u307e\u3042\u3001\u50d5\u306e\u63a8\u6e2c\u3067\u3059\u304c\u3001\u3001\u3001\u3002
\n\u3082\u3061\u308d\u3093\u3001\u5f31\u3044\u63a8\u5968\u3060\u304b\u3089\u3068\u3044\u3063\u3066\u3001\u884c\u306a\u308f\u306a\u3044\u5148\u751f\u3082\u3044\u3066\u3082\u826f\u3044\u3068\u8aac\u660e\u3057\u3066\u3082\u3067\u3059\u3002\u305d\u308c\u3060\u3051\u3001\u3053\u306e\u30d0\u30a4\u30a2\u30b9\u30ea\u30b9\u30af\u304c\u6df1\u523b\u306a\u8ad6\u65871\u3064\u3067\u3001\u884c\u306a\u3046\u3053\u3068\u3092\u63a8\u5968\u3068\u8a00\u3046\u3053\u3068\u3078\u306e\u62b5\u6297\u304c\u5f37\u3044\u3068\u601d\u3046\u306e\u3067\u3059\uff08\u50d5\u3082\u6c17\u6301\u3061\u306f\u3001\u305d\u3046\u3067\u3059\u304c\uff3e\uff3e\uff1b\uff09\u3002<\/b>\n<\/td>\n<\/tr>\n

\n

[\u76f8\u539f]
\n1.\u5177\u4f53\u7684\u306a\u5224\u65ad\u7406\u7531\u304c\u79c1\u306b\u306f\u308f\u304b\u308a\u307e\u305b\u3093\u304c\u3001\u305d\u306e999\u4eba\u306e\u65b9\u3005\u306f\u3001\u63a8\u5968\u306e\u95be\u5024\u3084\u4fa1\u5024\u89b3\u3092\u3069\u306e\u3088\u3046\u306b\u8a2d\u5b9a\u3057\u3066\u3044\u308b\u306e\u3067\u3057\u3087\u3046\u304b\uff1f<\/p>\n

2.\u307e\u305f\u3001\u76f4\u63a5\u6bd4\u8f03\u306e\u30e9\u30f3\u30c0\u30e0\u5316\u8a66\u9a13\u306b\u3053\u3060\u308f\u3063\u3066\u3044\u308b\u3068\u3044\u3046\u73fe\u72b6\u304c\u3042\u308b\u3068\u8003\u3048\u307e\u3059\u3002<\/p>\n

3.Urgent guideline\u3084Rapid guideline\u306b\u304a\u3044\u3066\u306f\u3001\u305d\u3093\u306a\u6642\u9593\u7684\u306a\u4f59\u88d5\u304c\u306a\u3044\u3053\u3068\u304c\u591a\u304f\u3001\u305f\u3068\u3048\u3070SARS-CoV-2\u306b\u95a2\u3059\u308b\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u4f5c\u6210\u306b\u304a\u3044\u3066\u3001\u5fc5\u8981\u3067\u3042\u308c\u3070MERS-CoV\u3084SARS-CoV1\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u3092\u6d3b\u7528\u3059\u308b\u3068\u3044\u3046\u624b\u6cd5\u3082\u3042\u308a\u307e\u3059\u3002\u307e\u305f\u3001animal studies\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u3092\u5229\u7528\u305b\u3056\u308b\u3092\u5f97\u306a\u3044\u72b6\u6cc1\u3082\u3042\u308a\u307e\u3059\u3002
\n\u3053\u3046\u306a\u308b\u3068\u3001indirectness\u304c\u975e\u5e38\u306b\u6df1\u523b\u3068\u306a\u3063\u3066\u304d\u307e\u3059\u3002<\/p>\n

4.\u8fc5\u901f\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u306b\u304a\u3044\u3066\u306f\u3001\u30a8\u30d3\u30c7\u30f3\u30b9\u304c\u7d99\u7d9a\u7684\u306b\u66f4\u65b0\u3055\u308c\u308bliving review\u304c\u5fc5\u9808\u3067\u3001living radid guideline\u3067\u3042\u308b\u3079\u304d\u3067\u3059\u3002<\/p>\n

5.\u3044\u305a\u308c\u3082GRADE\u30b7\u30b9\u30c6\u30e0\u306e\u57fa\u672c\u3067\u3059\u3002\n<\/td>\n<\/tr>\n

\n

\u6e6f\u6d45\u5148\u751f\uff1a
\n(6)\u30de\u30b8\u30c3\u30af\u3067\u3001\u30aa\u30fc\u30b9\u30c8\u30e9\u30ea\u30a2\uff08\u3053\u3061\u3089\u304c\u306e\u304c5\u670827\u65e5\u3068\u65b0\u3057\u3044\u3001\u30ab\u30ca\u30c0\u306f5\u67084\u65e5\uff09\u306e\u306b\u306f\u3001Favipiravir vs Arbidol\u304c\u306a\u304b\u3063\u305f\u306e\u3067\u3001\u7121\u3044\u3068\u601d\u3063\u3066\u3044\u307e\u3057\u305f\u304c\u3001\u3082\u3046\u4e00\u3064\u306e\u30d7\u30ed\u30b8\u30a7\u30af\u30c8\u306e\u65b9\u306b\u306f\u3042\u308a\u307e\u3057\u305f\u3002
\nhttps:\/\/app.magicapp.org\/#\/guideline\/4216<\/a><\/p>\n

\u6587\u732e\u304c\u3001\u76f8\u539f\u5148\u751f\u306e\u3068\u540c\u3058\u306e\u3092\u4f7f\u3063\u3066\u3044\u308b\u306e\u304b\u4e0d\u660e\u3067\u3001\u4ee5\u4e0b\u306e\u53c2\u8003\u6587\u732e\u3057\u304b\u3042\u308a\u307e\u305b\u3093\u3002\u30a2\u30a6\u30c8\u30ab\u30e0\u30821\u3064\u306e\u307f\u3068\u306e\u3053\u3068\u3002
\n[22] Liu W., Zhou P., Chen K. et al : Efficacy and safety of antiviral agents in COVID-19 patients: systematic review and meta-analysis (in submission). 2020;\n<\/td>\n<\/tr>\n

\n

[\u76f8\u539f]
\n\u540c\u3058\u6587\u732e\u3067\u3059\u304c\u3001MAGIC\u30d1\u30cd\u30eb\u306e\u8a55\u4fa1\u306f\u3001verious RoB, serious indirectness, very serious imprecision\u3067\u3001\u6700\u7d42\u7684\u306b\u300cVery Low\u300d\u306e\u5224\u5b9a\u3067\u3059\u3002<\/p>\n

\u63a8\u5968\uff1a\u300cWeak recommendation against\uff08in patients with non-severe COVID-19\uff09\u300d
\n\uff08GRADE 2D\uff09<\/b>
\n————————-
\n\"\"<\/a>
\n
\n 
\nWe are very uncertain of the effect of favipiravir on clinical recovery at day 7.<\/p>\n

[Preference and values]
\nFirst, when modest harms were present and there was low-quality evidence of a small but important difference in an outcome important to patients (e.g., mortality), most patients would choose to receive an intervention. That is, most patients would place a higher value on an uncertain, small but important benefit than in avoiding modest harms. Second, when low-quality evidence suggests little or no benefit, or when only very low-quality evidence exists and effects are therefore very uncertain, most patients would decline the intervention.
\n********************<\/p>\n

\u4ee5\u4e0b\u306fMAGIC\u30d1\u30cd\u30eb\u306e\u5224\u65ad\u306b\u95a2\u3059\u308b\u610f\u898b\u3067\u3059\u3002<\/p>\n

1.MAGIC\u30d1\u30cd\u30eb\u306f236\u4eba\u306e\u5168\u60a3\u8005\u304b\u3089\u76f8\u5bfe\u30ea\u30b9\u30af\u3092\u7b97\u51fa\u3057\u3066\u3044\u307e\u3059\u304c\u3001\u3053\u306e\u4e2d\u306b\u306f\u3001severe or critical patients\uff08Favipiravir\u7fa4=18\/116 vs Arbidol\u7fa4=9\/120, p=0.0658\uff09\u304c\u542b\u307e\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u3057\u305f\u304c\u3063\u3066\u3001\u3042\u3048\u3066\u300cnon-severe COVID-19\u300d\u3068\u3044\u3046\u30ab\u30c6\u30b4\u30ea\u3092\u4f5c\u6210\u3057\u305f\u3046\u3048\u3067\u306e\u63a8\u5968\u63d0\u793a\u306a\u3089\u3070\u3001236\u4eba\u306e\u60a3\u8005\u306eITT\u89e3\u6790\uff08\uff1f\uff09\u306b\u3088\u308bRR\u306f\u4e0d\u9069\u5207\u3068\u79c1\u306f\u601d\u3044\u307e\u3059\u3002<\/p>\n

2.\u307e\u305f\u3001indirectness=serious\u3068\u3044\u3046\u306e\u3082\u3069\u3046\u304b\u3068\u601d\u3044\u307e\u3059\u304c\u3002\u3002\u3002\u307e\u3042\u3053\u306e\u3088\u3046\u306a\u5224\u65ad\u3082\u3042\u308b\u306e\u3067\u3057\u3087\u3046\u3002
\n\u3044\u305a\u308c\u306b\u3057\u3066\u3082\u3001CoE\u306f\u300clow\u300d\u304b\u300cVery low\u300d\u3067\u3057\u3087\u3046\u3002<\/p>\n

3.Chen\u3089\u306e\u5831\u544a\u306b\u304a\u3044\u3066\u3001\u4e2d\u7b49\u75c7<\/b>\u306b\u9650\u308b\u3068\uff08EtD\u30c6\u30fc\u30d6\u30eb\u306b\u8a18\u8f09\u3057\u305f\u3088\u3046\u306b<\/b><\/a>\uff09 \u81e8\u5e8a\u56de\u5fa9\u7387\u30922\u5024\u5316\u3057\u305f\u5358\u7d14\u6bd4\u8f03\u3067\u306f\u8457\u8005\u304c\u767a\u8868\u3057\u3066\u3044\u308b\u3088\u3046\u306b\u7d71\u8a08\u7684\u306b\u3082\u6709\u610f\u3067\u3059\uff08RR= 1.28\uff1b1.04-1.57\u3001ARR 157 more\/1000; 25-287 more\/1000\uff09\u3002\n<\/td>\n<\/tr>\n<\/td>\n<\/tr>\n

\n

\u6e6f\u6d45\u5148\u751f\uff1a
\n(7)18 \u6b73\u4ee5\u4e0a\u306e\u4e2d\u7b49\u75c7 COVID-19 \u60a3\u8005\u306b\u5bfe\u3057\u3066\u3001Arbidol\u3088\u308a\u30a2\u30d3\u30ac\u30f3\u306e\u4f7f\u7528\u3092\u63d0\u6848\u3059\u308b\uff08GRADE 2C\uff09
\n\u3067\u306a\u304b\u3063\u305f\u306e\u306f\u3001\u3069\u306e\u3088\u3046\u306a\u30ed\u30b8\u30c3\u30af\u306b\u306a\u308b\u306e\u3067\u3057\u3087\u3046\u304b\u3002
\n\u3082\u3063\u3068\u3082\u3001Arbidol\u30fb\u30a6\u30a4\u30eb\u30b9\u306e\u4fb5\u5165\u963b\u5bb3\u85ac\u3067\u3001\u6cbb\u7642\u52b9\u679c\u306f\u3082\u3068\u3082\u3068\u306a\u3055\u305d\u3046\u306a\u306e\u3067\u3001\u672a\u6cbb\u7642\u307f\u305f\u3044\u306a\u3082\u306e\u3067\u3059\u3051\u3069\uff08\u5f37\u3044\u3066\u8a00\u3048\u3070\u5bb3\u3060\u3051\uff1f\uff1f\uff09\u3002<\/b><\/p>\n

\n

[\u76f8\u539f]
\n\u3053\u306e\u8ad6\u6587\u3067\u306f\u3001\u78ba\u304b\u306bcomparator\u306fArbidol\u3068\u3044\u3046\u6297\u30a6\u30a4\u30eb\u30b9\u85ac\u3067\u3059\u304c\u3001\u4e2d\u56fd\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3067\u306f\u6a19\u6e96\u7684\u6cbb\u7642\u3068\u3057\u3066\u4f4d\u7f6e\u3065\u3051\u3055\u308c\u3066\u3044\u308b\u3082\u306e\u306e\u3001\u6cbb\u7642\u306e\u6709\u52b9\u6027\u3092\u7372\u5f97\u3059\u308b\u306b\u306f\u4e0d\u5341\u5206\u306a\u91cf\u304b\u3082\u3057\u308c\u306a\u3044\u3068\u3055\u308c\u3066\u3044\u308b\u3082\u306e\u3067\u3059\u3002<\/p>\n

https:\/\/www.nature.com\/articles\/s41421-020-0169-8.pdf<\/a>
\n——————————————
\nHowever, the current dose of arbidol (200 mg, 3 times\/day) recommended by the Chinese Guidelines may not be able to achieve an ideal therapeutic efficacy to inhibit SARS-CoV-2 infection, and should be elevated.
\n——————————————<\/p>\n

\u306a\u306e\u3067\u3001MAGIC\u30d1\u30cd\u30eb\u306e\u201dcomparator=indirectness\u201d\u3068\u3044\u3046\u306e\u306f\u53b3\u3057\u3059\u304e\u308b\u3068\u79c1\u306f\u8003\u3048\u307e\u3059\u3002<\/p>\n

\u4eca\u56de\u306e\u30d6\u30ed\u30b0\u3067\u306e\u4e00\u9023\u306e\u8aac\u660e\u3067\u3082\u3001\u300c\u3053\u306e\u30a2\u30d3\u30ac\u30f3\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u306f\u3001\u5bfealbidol\u306b\u9650\u5b9a\u3057\u305f\u52b9\u679c\u306b\u95a2\u3059\u308b\u3082\u306e\u3067\u3059\u300d\u3068\u306f\u8a18\u8f09\u3057\u307e\u305b\u3093\u3067\u3057\u305f\u3002
\n\u30a2\u30d3\u30ac\u30f3\u306e\u5bb3\u306b\u95a2\u3059\u308b\u691c\u7d22\u306b\u304a\u3044\u3066\u3001\u30a8\u30dc\u30e9\u30a6\u30a4\u30eb\u30b9\u306e\u89b3\u5bdf\u7814\u7a76\u30a8\u30d3\u30c7\u30f3\u30b9\u3092\u63a1\u7528\u3057\u307e\u3057\u305f\u304c\u3001\u3053\u3061\u3089\u3082\u3001\u540c\u3058\u3088\u3046\u306b\u201dindirectness= not serious\u201d\u3068\u3057\u307e\u3057\u305f\u3002<\/p>\n

\u3067\u3082\u3001MAGIC\u30d1\u30cd\u30eb\u306f\u3001indirectness(-1)\u3068\u8a55\u4fa1\u3057\u3066\u304a\u308a\u3001\u3053\u306e\u8fba\u306f\u3044\u305a\u308c\u304c\u6b63\u3057\u3044\u304b\u3068\u3044\u3046\u3053\u3068\u3067\u306f\u306a\u3044\u3067\u3059\u3002<\/p>\n

\u3064\u307e\u308a\u3001\u300c\u5224\u65ad\u306e\u900f\u660e\u6027\u300d<\/b>\u304c\u91cd\u8981\u3067\u3059\u3002
\n\u63a8\u5968\u4e8b\u9805\u306e\u6700\u7d42\u30e6\u30fc\u30b6\u30fc\u304c\u3001\u533b\u7642\u63d0\u4f9b\u8005\u3068\u60a3\u8005\u304c\u6c7a\u5b9a\u3059\u308c\u3070\u3088\u3044\u3053\u3068\u3068\u601d\u3044\u307e\u3059\u3002<\/p>\n

\u3061\u306a\u307f\u306b\u3001MAGIC\u30d1\u30cd\u30eb\u306eArbidol\u306e\u5bfeStandard Care\u6bd4\u8f03\u3067\u306f\uff081\u4ef6\u306e\u7814\u7a76\u3067\u3001n=23\uff09\u3001\u30a6\u30a4\u30eb\u30b9\u30af\u30ea\u30a2\u30e9\u30f3\u30b9\u306f RR=1.23 (0.74-2.03)\u3067\u5168\u304f\u5dee\u304c\u306a\u3044\u3067\u3059\u3002
\n************<\/p>\n

Non-severe (Moderate) COVID-19\u306b\u9650\u3063\u305f\u30b5\u30d6\u30b0\u30eb\u30fc\u30d7\u52b9\u679c\u3067\u306f\u4ee5\u4e0b\u306e\u3088\u3046\u306b\u306a\u308a\u307e\u3059\u304c\u3001\u3055\u3059\u304c\u306b\u3001\u3053\u3061\u3089\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u306f\u300cvery low\u300d<\/b>\u3068\u601d\u3044\u307e\u3059\u3002<\/b><\/p>\n

\"\"<\/a><\/p>\n

Full Evidence profile\u306f\u3001\u3053\u3061\u3089<\/b><\/a>\u3002\n<\/td>\n<\/tr>\n<\/table>\n

\n <\/p>\n","protected":false},"excerpt":{"rendered":"

\u30a2\u30d3\u30ac\u30f3\u3092COVID-19\u6cbb\u7642\u306b\u4f7f\u7528\u3059\u3079\u304d\u304b\uff1a\uff08\uff12\uff09\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u78ba\u5b9f\u6027\u306f\u300clow\u300d\u306e\u8a18\u4e8b\u306b\u95a2\u3057\u3066\u3001\u53cb\u4eba\u306e\u6e6f\u6d45\u5148\u751f\uff08\u8c4a\u6a4b\u533b\u7642\u30bb\u30f3\u30bf\u30fc\u6b6f\u79d1\u53e3\u8154\u5916\u79d1\uff09\u304b\u3089\u30b3\u30e1\u30f3\u30c8\u3092\u3044\u305f\u3060\u3044\u305f\u306e\u3067\u3001\u5224\u65ad\u30d7\u30ed\u30bb\u30b9\u306b\u95a2\u3057\u3066\u3001GRADE\u3092\u4f7f\u304a\u3046\u3068\u3057\u3066 […]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[470],"tags":[],"_links":{"self":[{"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/posts\/10502"}],"collection":[{"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=10502"}],"version-history":[{"count":36,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/posts\/10502\/revisions"}],"predecessor-version":[{"id":11333,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/posts\/10502\/revisions\/11333"}],"wp:attachment":[{"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=10502"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=10502"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=10502"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}