{"id":10661,"date":"2020-06-08T15:00:29","date_gmt":"2020-06-08T06:00:29","guid":{"rendered":"http:\/\/aihara.la.coocan.jp\/?p=10661"},"modified":"2020-06-08T15:00:29","modified_gmt":"2020-06-08T06:00:29","slug":"%e3%80%8ccovid-19%e6%b2%bb%e7%99%82%e3%81%ae%e6%bd%9c%e5%9c%a8%e7%9a%84%e3%81%aa%e5%ae%b3%e3%81%af%e9%81%8e%e5%b0%8f%e8%a9%95%e4%be%a1%e3%81%95%e3%82%8c%e3%81%a6%e3%81%84%e3%82%8b%e3%80%8d%ef%bc%9aguy","status":"publish","type":"post","link":"http:\/\/aihara.la.coocan.jp\/?p=10661","title":{"rendered":"\u300cCOVID-19\u6cbb\u7642\u306e\u6f5c\u5728\u7684\u306a\u5bb3\u306f\u904e\u5c0f\u8a55\u4fa1\u3055\u308c\u3066\u3044\u308b\u300d\uff1aGuyatt"},"content":{"rendered":"<p>&nbsp;<br \/>\ncovid-19\u306b\u95a2\u3059\u308b\u3055\u307e\u3056\u307e\u306a\u767a\u8868\u306b\u3064\u3044\u3066\u3001EBM\u306e\u5927\u5fa1\u6240\u3001<b>Gordon Guyatt<\/b>\u306e\u30b3\u30e1\u30f3\u30c8\u304cMcMaster\u5927\u5b66\u306eweb\u30b5\u30a4\u30c8\u300cNews &#038; Events\u300d(4\/30)\u3067\u7d39\u4ecb\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<p><a href=\"https:\/\/healthsci.mcmaster.ca\/home\/2020\/04\/30\/potential-harms-of-covid-19-treatments-underappreciated-guyatt\"><img decoding=\"async\" loading=\"lazy\" src=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2020\/06\/gordon_vs_COVID.jpg\" alt=\"\" width=\"902\" height=\"379\" class=\"alignnone size-full wp-image-10665\" srcset=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2020\/06\/gordon_vs_COVID.jpg 902w, http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2020\/06\/gordon_vs_COVID-300x126.jpg 300w, http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2020\/06\/gordon_vs_COVID-768x323.jpg 768w\" sizes=\"(max-width: 902px) 100vw, 902px\" \/><\/a><\/p>\n<div style=\"font-size: 1.2em\">\n<p><span style=\"color:#008080\"><b>\u300cCOVID-19\u6cbb\u7642\u306e\u6f5c\u5728\u7684\u306a\u5bb3\u306f\u904e\u5c0f\u8a55\u4fa1\u3055\u308c\u3066\u3044\u308b\u300d<\/b><\/span><\/p>\n<\/div>\n<table summary=\"Guyatt COVID-19\" width=\"100%\" border=\"1\" style=\"border-collapse:collapse;border:none;\">\n<tr>\n<td style=\"border:1px solid #000000; padding:5px; background:#ffffff;\">\n\u533b\u5e2b\u3001\u85ac\u5264\u5e2b\u3001\u533b\u5b66\u7814\u7a76\u8005\u3001\u60a3\u8005\u30d1\u30fc\u30c8\u30ca\u30fc\u306e\u56fd\u969b\u7684\u306a\u30c1\u30fc\u30e0\u304c\u3001COVID-19\u60a3\u8005\u306e\u6cbb\u7642\u306b\u95a2\u3059\u308b\u81e8\u5e8a\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3092\u4f5c\u6210\u3057\u307e\u3057\u305f\u3002<\/p>\n<p>\u3053\u306e\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u306f\u3001<a href=\"https:\/\/www.cmaj.ca\/content\/192\/20\/E536\"><b><i>Canadian Medical Association Journal\uff08CMAJ\uff09<\/i><\/b><\/a>\u3067\u516c\u958b\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<p> <a href=\"https:\/\/app.magicapp.org\/#\/guidelines\"><b>MAGICApp<\/b><\/a>\u3067\u306f\u3001\u81e8\u5e8a\u533b\u3060\u3051\u3067\u306a\u304f\u60a3\u8005\u306b\u3068\u3063\u3066\u3082\u3001\u30e6\u30fc\u30b6\u30fc\u30d5\u30ec\u30f3\u30c9\u30ea\u30fc\u306a\u3055\u307e\u3056\u307e\u306a\u5f62\u5f0f\u3067\u5229\u7528\u3067\u304d\u307e\u3059\u3002<br \/>\n\u300cCOVID-19\u306e\u5065\u5eb7\u3078\u306e\u60aa\u5f71\u97ff\u306e\u751a\u5927\u3055\u3092\u8003\u3048\u308b\u3068\u3001\u9032\u884c\u3092\u9045\u3089\u305b\u3001\u6b7b\u4ea1\u3092\u56de\u907f\u3057\u3001\u56de\u5fa9\u3092\u52a0\u901f\u3059\u308b\u305f\u3081\u306e\u4ecb\u5165\u3092\u81e8\u5e8a\u533b\u3068\u60a3\u8005\u304c\u5207\u671b\u3059\u308b\u306e\u306f\u7121\u7406\u3082\u306a\u3044\u8a71\u3067\u3059\u300d\u3068\u3001\u672c\u7a3f\u306e\u8cac\u4efb\u8457\u8005\u3067\u3042\u308a\u3001\u30de\u30af\u30de\u30b9\u30bf\u30fc\u5927\u5b66\uff08McMaster University\uff09\u306eDepartment of Health Research Methods, Evidence and Impact\u6559\u6388\u3067\u3082\u3042\u308bGordon Guyatt\u6c0f\u306f\u8ff0\u3079\u308b\u3002 <\/p>\n<p>\u300c\u305f\u3060\u3001\u305d\u306e\u601d\u3044\u304c\u5f37\u3059\u304e\u308b\u3053\u3068\u304c\u3001\u5c02\u9580\u5bb6\u3084\u898f\u5236\u5f53\u5c40\u3001\u305d\u3057\u3066\u8457\u540d\u306a\u653f\u6cbb\u5bb6\u304c\u6cbb\u7642\u306b\u671f\u5f85\u3055\u308c\u308b\u5229\u76ca\u3092\u904e\u5ea6\u306b\u697d\u89b3\u8996\u3057\u3001\u305d\u306e\u6f5c\u5728\u7684\u306a\u5bb3\u3092\u904e\u5c0f\u8a55\u4fa1\u3059\u308b\u3053\u3068\u306b\u3064\u306a\u304c\u3063\u3066\u3044\u308b\u306e\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002\u300d<\/p>\n<p>\u533b\u5e2b\u304a\u3088\u3073\u60a3\u8005\u5411\u3051\u306e\u3053\u306e\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u306f\u30012020\u5e744\u670825\u65e5\u6642\u70b9\u3067\u5165\u624b\u53ef\u80fd\u306a\u6700\u65b0\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u306b\u57fa\u3065\u3044\u3066\u304a\u308a\u3001COVID-19\u306e\u91cd\u75c7\u304a\u3088\u3073\u975e\u91cd\u75c7\u60a3\u8005\u3092\u5bfe\u8c61\u3068\u3057\u305f\u6cbb\u7642\u306b\u3064\u3044\u3066\u691c\u8a0e\u3057\u3066\u3044\u308b\u3002\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u8cea\u3092\u7dcf\u5408\u7684\u306b\u8a55\u4fa1\u3057\u3066\u307f\u305f\u3068\u3053\u308d\u3001\u6cbb\u7642\u306e\u5229\u76ca\u3092\u652f\u6301\u3059\u308b\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u8cea\u306f\u300c\u4f4e\uff08Low\uff09\u300d\u307e\u305f\u306f\u300c\u975e\u5e38\u306b\u4f4e\uff08Very low\uff09\u300d\u306e\u3082\u306e\u3070\u304b\u308a\u3067\u3042\u3063\u305f\u3002<\/p>\n<p>\u300c\u305d\u306e\u7d50\u679c\u3001COVID-19\u60a3\u8005\u3078\u306e\u4e00\u9023\u306e\u85ac\u5264\u306e\u4f7f\u7528\u306b\u5bfe\u3057\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u30d1\u30cd\u30eb\u304c\u793a\u3057\u305f\u63a8\u5968\u306e\u307b\u3068\u3093\u3069\u304c\u3001\u5f31\u3044\u63a8\u5968\u307e\u305f\u306f\u6761\u4ef6\u7684\u63a8\u5968\u3067\u3057\u305f\u300d\u3068Guyatt\u306f\u8a00\u3046\u3002<\/p>\n<p>\u8cea\u304c\u300c\u975e\u5e38\u306b\u4f4e\u300d\u3068\u8a55\u4fa1\u3055\u308c\u308b2\u3064\u306e\u7814\u7a76\u306b\u3088\u308a\u3001\u30d2\u30c9\u30ed\u30ad\u30b7\u30af\u30ed\u30ed\u30ad\u30f3\u304c\u4eba\u5de5\u547c\u5438\u5668\u88c5\u7740\u3068\u6b7b\u4ea1\u306e\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3053\u3068\u304c\u6307\u6458\u3055\u308c\u3066\u3044\u308b\u3053\u3068\u306b\u8457\u8005\u3089\u306f\u6ce8\u610f\u3092\u4fc3\u3057\u3066\u3044\u308b\u3002<br \/>\n<b><br \/>\n\u2022\u91cd\u75c7\u306eCOVID-19\u3067\u6025\u6027\u547c\u5438\u7aae\u8feb\u75c7\u5019\u7fa4\uff08ARDS\uff09\u3092\u4f34\u3046\u60a3\u8005\u306b\u30b3\u30eb\u30c1\u30b3\u30b9\u30c6\u30ed\u30a4\u30c9\u306e\u4f7f\u7528\u3092\u652f\u6301\u3059\u308b\u5f31\u3044\u63a8\u5968<br \/>\n\u2022COVID-19\u3067ARDS\u306e\u306a\u3044\u60a3\u8005\u306b\u30b3\u30eb\u30c1\u30b3\u30b9\u30c6\u30ed\u30a4\u30c9\u306e\u4f7f\u7528\u306b\u53cd\u5bfe\u3059\u308b\u5f31\u3044\u63a8\u5968<br \/>\n\u2022\u91cd\u75c7\u306eCOVID-19\u60a3\u8005\u306b\u56de\u5fa9\u671f\u8840\u6f3f\u306e\u4f7f\u7528\u306b\u53cd\u5bfe\u3059\u308b\u5f31\u3044\u63a8\u5968<br \/>\n\u2022\u91cd\u75c7\u304a\u3088\u3073\u975e\u91cd\u75c7\u306eCOVID-19\u60a3\u8005\u306e\u6cbb\u7642\u306e\u305f\u3081\u306b\u73fe\u5728\u691c\u8a0e\u4e2d\u306e\u3044\u304f\u3064\u304b\u306e\u6297\u30a6\u30a4\u30eb\u30b9\u85ac\u306e\u4f7f\u7528\u306b\u53cd\u5bfe\u3059\u308b\u5f31\u3044\u63a8\u5968\u3002<br \/>\n<\/b><br \/>\n\u300c\u3053\u306e\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3067\u306f\u3001\u533b\u7642\u8cc7\u6e90\u306e\u6d6a\u8cbb\u3092\u6e1b\u3089\u3059\u610f\u5473\u3067\u3082\u3001\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u8cea\u304c\u300c\u975e\u5e38\u306b\u4f4e\u300d\u3068\u8a55\u4fa1\u3055\u308c\u308b\u4ecb\u5165\u306e\u4f7f\u7528\u306f\u63a7\u3048\u308b\u3088\u3046\u63a8\u5968\u3059\u3079\u304d\u3067\u3059\u3002\u3057\u304b\u3057\u3001\u308f\u308c\u308f\u308c\u304c\u73fe\u6642\u70b9\u3067\u306f\u305d\u306e\u5229\u76ca\u306b\u95a2\u3059\u308b\u78ba\u56fa\u305f\u308b\u30a8\u30d3\u30c7\u30f3\u30b9\u3092\u307f\u3064\u3051\u308b\u3053\u3068\u304c\u3067\u304d\u306a\u304b\u3063\u305f\u85ac\u7269\u306e\u4f7f\u7528\u3092\u652f\u6301\u3059\u308b\u3088\u3046\u306a\u8aa4\u89e3\u3092\u62db\u304f\u610f\u898b\u304c\u3042\u308b\u3053\u3068\u304c\u3001\u3053\u306e\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u306e\u5b9f\u884c\u3092\u963b\u3080\u5927\u304d\u306a\u969c\u58c1\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u300d\u3068\u8457\u8005\u3089\u306f\u7d50\u8ad6\u4ed8\u3051\u308b\u3002\n<\/td>\n<\/tr>\n<\/table>\n<p>***********************<\/p>\n<p>\u3053\u306e\u5185\u5bb9\u306f\u30014\/30\u306e\u6642\u70b9\u3067\u3059\u304c\u3001\u305d\u306e\u5f8c\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u30a2\u30c3\u30d7\u30c7\u30fc\u30c8\uff086\/4\uff09\u3067\u306f\u3001\u524d\u56de\u7d39\u4ecb\u3057\u305f\u3088\u3046\u306b\u3001<b>Remdesivir<\/b>\u304c\u300cWeak recommendation\u300d\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002<br \/>\n<a href=\"https:\/\/app.magicapp.org\/#\/guideline\/4249\">https:\/\/app.magicapp.org\/#\/guideline\/4249<\/a><\/p>\n<div style=\"font-size: 0.9em\">\n<p><b>\u6ce8\uff1aMAGIC\u30d1\u30cd\u30eb\u306e\u4fa1\u5024\u89b3\u3084\u610f\u5411\u306b\u95a2\u3059\u308b\u5224\u65ad\uff1a<\/b><br \/>\nFirst, when modest harms were present and there was low-quality evidence of a small but important difference in an outcome important to patients (e.g., mortality), most patients would choose to receive an intervention. That is, most patients would place a higher value on an uncertain, small but important benefit than in avoiding modest harms.<br \/>\nSecond, when low-quality evidence suggests little or no benefit, or when only very low-quality evidence exists and effects are therefore very uncertain, most patients would decline the intervention.<\/p>\n<\/div>\n<p>\n&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>&nbsp; covid-19\u306b\u95a2\u3059\u308b\u3055\u307e\u3056\u307e\u306a\u767a\u8868\u306b\u3064\u3044\u3066\u3001EBM\u306e\u5927\u5fa1\u6240\u3001Gordon Guyatt\u306e\u30b3\u30e1\u30f3\u30c8\u304cMcMaster\u5927\u5b66\u306eweb\u30b5\u30a4\u30c8\u300cNews &#038; Events\u300d(4\/30)\u3067\u7d39\u4ecb\u3055\u308c\u3066\u3044\u307e\u3059 [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[470],"tags":[],"_links":{"self":[{"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/posts\/10661"}],"collection":[{"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=10661"}],"version-history":[{"count":11,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/posts\/10661\/revisions"}],"predecessor-version":[{"id":10674,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/posts\/10661\/revisions\/10674"}],"wp:attachment":[{"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=10661"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=10661"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=10661"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}