{"id":10689,"date":"2020-06-11T10:27:57","date_gmt":"2020-06-11T01:27:57","guid":{"rendered":"http:\/\/aihara.la.coocan.jp\/?p=10689"},"modified":"2020-06-11T10:27:57","modified_gmt":"2020-06-11T01:27:57","slug":"40%e5%b9%b4%e9%96%93%e3%81%ae%e6%96%b0%e4%b8%96%e4%bb%a3%e6%8a%97%e3%81%86%e3%81%a4%e8%96%ac%e3%81%ae%e7%b4%af%e7%a9%8d%e3%83%8d%e3%83%83%e3%83%88%e3%83%af%e3%83%bc%e3%82%af%e3%83%a1%e3%82%bf%e3%82%a2","status":"publish","type":"post","link":"http:\/\/aihara.la.coocan.jp\/?p=10689","title":{"rendered":"40\u5e74\u9593\u306e\u65b0\u4e16\u4ee3\u6297\u3046\u3064\u85ac\u306e\u7d2f\u7a4d\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\uff1a\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u9032\u5316\u3092\u8996\u899a\u5316\u3059\u308b"},"content":{"rendered":"

Visualizing the evolution of evidence: Cumulative network meta-analyses of new generation antidepressants in the last 40 years<\/b>
\nRes Syn Meth. 2020;1\u201312. https:\/\/doi.org\/10.1002\/jrsm.1413<\/a><\/p>\n

\u4eac\u90fd\u306e\u53e4\u5ddd\u5148\u751f\u3068\u3001Chaimani. Cipriani, Salanti\u3089\u306e\u5171\u540c\u7814\u7a76\u3067\u3001\u7247\u5ca1\u5148\u751f\u3001\u5c0f\u5ddd\u5148\u751f\u3082\u53c2\u52a0\u3057\u3066\u3044\u307e\u3059\u306d\u3002<\/p>\n

\"\"<\/a><\/p>\n

\u65b0\u4e16\u4ee3\u6297\u3046\u3064\u85ac\u306b\u95a2\u3059\u308b\u6709\u52b9\u6027\u3068\u8a31\u5bb9\u53ef\u80fd\u6027\u3092\u6bd4\u8f03\u3059\u308b\u5f93\u6765\u306e\u5185\u5bb9\u3067\u3059\u304c\u300140\u5e74\u306b\u308f\u305f\u308b\u63a8\u79fb\u3084\u3001\u30c7\u30fc\u30bf\u306e\u5229\u7528\u53ef\u80fd\u6027\u3084\u89e3\u91c8\u53ef\u80fd\u6027\u3092\u5927\u5e45\u306b\u5411\u4e0a\u3057\u305fweb\u30c4\u30fc\u30eb\uff08*\uff09\u3092\u4f7f\u3063\u3066\u308f\u304b\u308a\u3084\u3059\u3044NMA\u7d50\u679c\u3092\u51fa\u529b\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n

*: https:\/\/cinema.ispm.unibe.ch\/shinies\/GRISELDA\/<\/b><\/span><\/a><\/p>\n

\u25a0\u57fa\u672c\u7684\u624b\u6cd5\u3068\u30c7\u30fc\u30bf\uff1a<\/b>
\nnetmeta 1.1-0 package in R (version 3.6.0)\u3000randomeffects model (\u52b9\u679c\u6307\u6a19OR)
\nCINeMA<\/a> (Confidence in Network Meta-Analysis) framework21
\n\u30c7\u30fc\u30bf\uff1ahttps:\/\/github.com\/y-luo06\/cNMA_of_antidepressant<\/a><\/p>\n

\u25a0\u51fa\u529b\uff1a<\/b>
\n\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u30d7\u30ed\u30c3\u30c8\u3001\uff12\u6b21\u5143\u30d7\u30ed\u30c3\u30c8\u3001\u30d5\u30a9\u30ec\u30b9\u30c8\u30d7\u30ed\u30c3\u30c8\u3002\u30ea\u30fc\u30b0\u30c6\u30fc\u30d6\u30eb\u3001\u30da\u30a2\u30ef\u30a4\u30ba\u6bd4\u8f03\u3001\u30d5\u30a1\u30f3\u30cd\u30eb\u30d7\u30ed\u30c3\u30c8\uff08comarison adjusted\uff09\u3001\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u9032\u5316\uff081978\uff5e2016\u5e74\uff09\u3067\u3059\u3002<\/p>\n

\u30ea\u30fc\u30b0\u30c6\u30fc\u30d6\u30eb\u30842\u6b21\u5143\u30d7\u30ed\u30c3\u30c8\u3067\u306f\u3001\u85ac\u85ac\u7269\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u78ba\u5b9f\u6027\u30924\u6bb5\u968e\u3067\u30ab\u30e9\u30fc\u8868\u793a\u3057\u3066\u3044\u307e\u3059\uff08\u7dd1\u8272\uff1dHigh\u3001\u9752\u8272\uff1dModerate\u3001\u9ec4\u8272\uff1dLow\u3001\u8d64\u8272\uff1dVery low\uff1b GRADE confidence\uff09\uff08\u4f8b\u3001\u56f3\uff11\uff09<\/p>\n

\u56f3\uff11\uff0eTwo-dimensional plots<\/b>
\nabout efficacy, acceptability and confidence
\n\"\"<\/a><\/p>\n

\uff12\u3064\u306e\u30a2\u30a6\u30c8\u30ab\u30e0\u6307\u6a19\u3092\u4e8c\u6b21\u5143\u30d7\u30ed\u30c3\u30c8\u3059\u308b\u3053\u3068\u3067\u3001\u53f3\u4e0a\u306b\u7dd1\u8272\u3067\u30d7\u30ed\u30c3\u30c8\u3055\u308c\u308b\u85ac\u7269\u304c\u63a8\u5968\u3055\u308c\u3001\u5de6\u4e0b\u306b\u8d64\u8272\u3067\u30d7\u30ed\u30c3\u30c8\u3055\u308c\u308b\u85ac\u7269\u304c\u304a\u52e7\u3081\u3067\u304d\u306a\u3044<\/b>\u3053\u3068\u304c\u793a\u5506\u3055\u308c\u307e\u3059\u3002\u3053\u306e\u56f3\u3067\u306f\u300c\u30dc\u30eb\u30c1\u30aa\u30ad\u30bb\u30c1\u30f3\u300d\u304c\u8a72\u5f53\u3057\u3066\u3044\u307e\u3059\u304c\u3001\u672c\u6587\u306b\u306f\u4ee5\u4e0b\u306e\u6ce8\u8a18\u304c\u3042\u308a\u307e\u3059\u3002
\n———————————————–
\nvortioxetine was introduced and appeared to have the best efficacy and tolerability, however, the precision was very low. Our results implied that the findings for vortioxetine might be too optimistic and we should wait some years to see its real effect.
\n———————————————–
\n\u307e\u305f\u3001
\n20\u5e74\u4ee5\u4e0a\u306b\u308f\u305f\u3063\u3066\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u9032\u5316\u304c\u89b3\u5bdf\u3055\u308c\u305f\u85ac\u7269\u306e\u4e2d\u3067\u3001\u307b\u3068\u3093\u3069\u3059\u3079\u3066\uff08\u30d5\u30eb\u30dc\u30ad\u30b5\u30df\u30f3\u3092\u9664\u304f\uff09\u304c\u5e02\u5834\u306b\u6295\u5165\u3055\u308c\u305f\u5f8c\u3001\u6709\u52b9\u6027\u306e\u63a8\u5b9a\u5024\u306b\u9855\u8457\u306a\u4f4e\u4e0b\u304c\u898b\u3089\u308c\u3001\u901a\u5e38\u306f\u5b89\u5b9a\u3059\u308b\u307e\u306710\u5e74\u4ee5\u4e0a\u304b\u304b\u3063\u3066\u3044\u305f\u3002\u65b0\u85ac\u306f\u3001\u767a\u58f2\u3055\u308c\u305f\u3068\u304d\u306b\u71b1\u72c2\u7684\u306a\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u3092\u793a\u3059\u50be\u5411\u304c\u3042\u308b\u3053\u3068\u3092\u793a\u3057\u3066\u3044\u308b\u3001\u3068\u3082\u8a18\u8f09\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

***********
\n\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u30a8\u30d3\u30c7\u30f3\u30b9\u306b\u95a2\u3057\u3066\u306f\u3001Salati\u30b0\u30eb\u30fc\u30d7\u3068GRADE NMA\u30b0\u30eb\u30fc\u30d7\uff08Puhan\uff09\u306e\uff12\u3064\u306e\u30d5\u30ec\u30fc\u30e0\u30ef\u30fc\u30af\u304c\u3042\u308a\u307e\u3059\u3002
\n\u30b3\u30af\u30e9\u30f3\u30cf\u30f3\u30c9\u30d6\u30c3\u30af11.5\u7ae0<\/b><\/a>\u306b\u306f\u3001\uff12\u3064\u306e\u6bd4\u8f03\u304c\u3088\u304f\u89e3\u8aac\u3055\u308c\u3066\u3044\u307e\u3059\u3002
\n
\n <\/p>\n","protected":false},"excerpt":{"rendered":"

Visualizing the evolution of evidence: Cumulative network meta-analyses of new generation antidepressants in t […]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[458],"tags":[],"_links":{"self":[{"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/posts\/10689"}],"collection":[{"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=10689"}],"version-history":[{"count":7,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/posts\/10689\/revisions"}],"predecessor-version":[{"id":10698,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/posts\/10689\/revisions\/10698"}],"wp:attachment":[{"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=10689"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=10689"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=10689"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}