{"id":11683,"date":"2021-05-10T11:28:58","date_gmt":"2021-05-10T02:28:58","guid":{"rendered":"http:\/\/aihara.la.coocan.jp\/?p=11683"},"modified":"2021-06-22T11:17:53","modified_gmt":"2021-06-22T02:17:53","slug":"%e5%ae%8c%e5%85%a8%e3%82%b3%e3%83%b3%e3%83%86%e3%82%ad%e3%82%b9%e3%83%88%e5%8c%96%e3%82%a2%e3%83%97%e3%83%ad%e3%83%bc%e3%83%81_4%ef%bc%9a%e9%87%8d%e5%a4%a7%e3%82%a2%e3%82%a6%e3%83%88%e3%82%ab%e3%83%a0","status":"publish","type":"post","link":"http:\/\/aihara.la.coocan.jp\/?p=11683","title":{"rendered":"\u5b8c\u5168\u30b3\u30f3\u30c6\u30ad\u30b9\u30c8\u5316\u30a2\u30d7\u30ed\u30fc\u30c1_4\uff1a\u91cd\u5927\u30a2\u30a6\u30c8\u30ab\u30e0\u306e\u76f8\u5bfe\u7684\u91cd\u8981\u6027\uff08step_2\uff09"},"content":{"rendered":"<p>\u30b7\u30ca\u30ea\u30aa\u3067\u306f\u3001\u30b9\u30c6\u30c3\u30d7\uff11\u306b\u304a\u3044\u3066\u3001\u4f75\u5408\u3055\u308c\u308b\u91cd\u5927\u30a2\u30a6\u30c8\u30ab\u30e0\u3092\uff14\u3064\u6c7a\u5b9a\u3057\u307e\u3057\u305f\u3002<br \/>\n\u5404\u30a2\u30a6\u30c8\u30ab\u30e0\u306b\u95a2\u3059\u308b\u30a8\u30d3\u30c7\u30f3\u30b9\u3068\u305d\u306e\u78ba\u5b9f\u6027\u3092\u8981\u7d04\u3057\u305f\u3082\u306e\u304c\u4ee5\u4e0b\u3067\u3059\u3002<\/p>\n<table summary=\"sof\" border=\"1\" style=\"border-collapse:collapse;border:none;\">\n<tr>\n<td style=\"border:1px solid #000000; padding:5px; background:#dcdcdc;\"\"><b>\u30a2\u30a6\u30c8\u30ab\u30e0<\/b><\/td>\n<td style=\"border:1px solid #000000; padding:5px; background:#dcdcdc;\"\"><b>\u60a3\u80051000\u4eba\u3042\u305f\u308a\u306e\u7d76\u5bfe\u52b9\u679c\u63a8\u5b9a\u5024(95%CI)<\/b><\/td>\n<td style=\"border:1px solid #000000; padding:5px; background:#dcdcdc;\"\"><b>\u52b9\u679c\u63a8\u5b9a\u5024\u306e\u78ba\u5b9f\u6027(*)<\/b><\/td>\n<\/tr>\n<tr>\n<td style=\"border:1px solid #000000; padding:5px;\"><b>\u5168\u539f\u56e0\u6b7b\u4ea1<\/b><\/td>\n<td style=\"border:1px solid #000000; padding:5px;\"><b>-12 (-107 \uff5e +93)<\/b><\/td>\n<td style=\"border:1px solid #000000; padding:5px;\"><b>Low<\/b> (RoB, indirectness)<\/td>\n<\/tr>\n<tr>\n<td style=\"border:1px solid #000000; padding:5px;\"><b>\u5c40\u6240\u518d\u767a<\/b><\/td>\n<td style=\"border:1px solid #000000; padding:5px;\"><b>-17 (-109 \uff5e +98)<\/b><\/td>\n<td style=\"border:1px solid #000000; padding:5px;\"><b>Low<\/b> (RoB, indirectness)<\/td>\n<\/tr>\n<tr>\n<td style=\"border:1px solid #000000; padding:5px;\"><b>\u9060\u9694\u8ee2\u79fb<\/b><\/td>\n<td style=\"border:1px solid #000000; padding:5px;\"><b>-9 (-35 \uff5e +28)<\/b><\/td>\n<td style=\"border:1px solid #000000; padding:5px;\"><b>Low<\/b> (RoB, indirectness)<\/td>\n<\/tr>\n<tr>\n<td style=\"border:1px solid #000000; padding:5px;\"><b>\u91cd\u7be4\u6709\u5bb3\u4e8b\u8c61<\/b><\/td>\n<td style=\"border:1px solid #000000; padding:5px;\"><b>+59.5 (+1.4 \uff5e +700)<\/b><\/td>\n<td style=\"border:1px solid #000000; padding:5px;\"><b>Low<\/b> (RoB, indirectness)<\/td>\n<\/tr>\n<\/table>\n<div style=\"font-size: 0.85em\">\n<p>\n*: \u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u78ba\u5b9f\u6027\u306b\u3064\u3044\u3066\u4e0d\u7cbe\u78ba\u3055\u306e\u305f\u3081\u306e\u8a55\u4fa1\uff08\u7b49\u7d1a\u30c0\u30a6\u30f3\uff09\u306f\u3057\u306a\u3044\u3002<br \/>\n\u6ce8\uff11\uff0e\u30aa\u30ea\u30b8\u30ca\u30eb\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\uff1a<a href=\"http:\/\/www.grade-jpn.com\/evidence_profile_0501.pdf\"><b>evidence_profile_0501.pdf<\/b><\/a><br \/>\n\u6ce8\uff12\uff0e\u91cd\u7be4\u6709\u5bb3\u4e8b\u8c61\u30a2\u30a6\u30c8\u30ab\u30e0\u306e\u30d5\u30a9\u30ec\u30b9\u30c8\u30d7\u30ed\u30c3\u30c8\uff1a<a href=\"http:\/\/www.grade-jpn.com\/forest_plot_SAE.jpg\"><b>forest_plot_SAE.jpg<\/b><\/a><\/p>\n<\/div>\n<p>\n&nbsp;<\/p>\n<div style=\"font-size: 1.5em\">\n<p><span style=\"color:#008080\"><b>\u25cf\u30b9\u30c6\u30c3\u30d7\uff12\uff1a\u5404\u30a2\u30a6\u30c8\u30ab\u30e0\u306e\u76f8\u5bfe\u7684\u91cd\u8981\u6027\u306e\u6c7a\u5b9a<\/b><\/span><\/p>\n<\/div>\n<p>\u5b8c\u5168\u30b3\u30f3\u30c6\u30ad\u30b9\u30c8\u5316\u30a2\u30d7\u30ed\u30fc\u30c1\uff08Alper\uff09\u306e\u7b2c2\u30b9\u30c6\u30c3\u30d7\u306f\u3001\u5404\u30a2\u30a6\u30c8\u30ab\u30e0\u306e\u76f8\u5bfe\u7684\u91cd\u8981\u6027\u3092\u6c7a\u5b9a\u3059\u308b\u3053\u3068\u3067\u3059\u3002<br \/>\n\uff08Alper BS, Oettgen P, Kunnamo I, et al. Defining certainty of net benefit: a GRADE concept paper. BMJ Open 2019;9:e027445. <a href=\"https:\/\/bmjopen.bmj.com\/content\/9\/6\/e027445\">doi:10.1136\/bmjopen-2018-027445<\/a>\uff09<\/p>\n<p>\u5207\u9664\u53ef\u80fd\u306a\u53e3\u8154\u304c\u3093\u60a3\u8005\u306e\u8853\u524d\u5316\u5b66\u7642\u6cd5\u306b\u3088\u308b\u5168\u539f\u56e0\u6b7b\u4ea1\u3092\u53c2\u7167\u5358\u4f4d\uff08\uff1d\uff11\uff09\u3068\u3057\u3066\u3001\u4ed6\u306e\uff13\u3064\u306e\u30a2\u30a6\u30c8\u30ab\u30e0\u306e\u91cd\u8981\u6027\u3092\u6c7a\u5b9a\u3057\u307e\u3059\uff08\u3053\u3053\u3067\u306f\u3001\u30a2\u30a6\u30c8\u30ab\u30e0\u306e\u91cd\u8981\u6027\u306e\u8cea\u7684\uff19\u30dd\u30a4\u30f3\u30c8\u8a55\u4fa1\u306e\u30b9\u30b3\u30a2\u306f\u95a2\u4fc2\u306a\u3044\u3067\u3059\uff09\u3002<br \/>\n\u76f8\u5bfe\u7684\u91cd\u8981\u6027\u306f\u4ee5\u524d\u306f\u300c\u4fa1\u5024\u89b3\u3084\u9078\u597d\uff08values and preferences\uff09\u300d\u3068\u547c\u3070\u308c\u3066\u3044\u305f\u3082\u306e\u3067\u3059\u304c\u3001\u4f8b\u3048\u3070\u6c7a\u65ad\u5206\u6790\u306e\u52b9\u7528\u5024\u306e\u3088\u3046\u306b\u3001\u4e0d\u52b9\u7528\u5024\uff08disutility = [1- utility]\uff09\u3092\u4f7f\u3063\u3066\u3001\u76f8\u5bfe\u7684\u91cd\u8981\u6027\u306b\u5909\u63db\u3067\u304d\u307e\u3059\u3002<\/p>\n<p>\u76f8\u5bfe\u7684\u91cd\u8981\u6027\u3084\u4e0d\u52b9\u7528\u5024\u306b\u95a2\u3059\u308b\u8a73\u7d30\u306f\u3001\u539f\u8457\u3042\u308b\u3044\u306f\u3001<a href=\"http:\/\/www.grade-jpn.com\/grade3e_cover.html\">GRADE3\u7248<\/a>\u306e2.4-2.1(p146)\u3092\u53c2\u7167\u304f\u3060\u3055\u3044\u3002<br \/>\n\uff08\u5f53\u7136\u306a\u304c\u3089\u3001GRADE3\u7248\u3067\u89e3\u8aac\u3057\u3066\u3044\u308b\u5b8c\u5168\u30b3\u30f3\u30c6\u30ad\u30b9\u30c8\u5316\u30a2\u30d7\u30ed\u30fc\u30c1\u306f\u3001\u4eca\u56de\u8aac\u660e\u3057\u3066\u3044\u308b\u624b\u6cd5\u3068\u306f\u7570\u306a\u3063\u3066\u3044\u307e\u3059\u3002Hultcrantz M, et al. The GRADE Working Group clarifies the construct of certainty of evidence. JCE 2017\uff09<\/p>\n<p>\u76f8\u5bfe\u7684\u91cd\u8981\u6027\u306f\u3001\u5358\u4e00\u306e\u5909\u63db\u4fc2\u6570\uff08\u4f8b\u30010.7\uff09\u3068\u3044\u3046\u3088\u308a\u306f\u3001\u201d\u3042\u308b\u7bc4\u56f2\u201d\u3068\u3044\u3046\u306e\u304c\u73fe\u5b9f\u7684\u3067\u3059\u304c\u3001\u3053\u306e\u70b9\u306f\u5f8c\u306e\u30b9\u30c6\u30c3\u30d7\uff16\u3067\u611f\u5ea6\u5206\u6790\u3059\u308b\u3053\u3068\u306b\u306a\u308a\u307e\u3059\u3002<br \/>\n\u3044\u305a\u308c\u306b\u3057\u3066\u3082\u3001\u3053\u306e\u30b9\u30c6\u30c3\u30d7\uff12\uff08\u5404\u30a2\u30a6\u30c8\u30ab\u30e0\u306e\u76f8\u5bfe\u7684\u91cd\u8981\u6027\u306e\u6c7a\u5b9a\uff09\u3067\u306f\u5229\u5bb3\u95a2\u4fc2\u8005\u306e\u610f\u898b\u3092\u53cd\u6620\u3055\u305b\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n<p>\u5168\u539f\u56e0\u6b7b\u4ea1\u304c\u53c2\u7167\u5358\u4f4d\u3068\u307f\u306a\u3055\u308c\u3001\u4f8b\u3048\u3070\u3001\u60a3\u8005\u304c\u5c40\u6240\u518d\u767a\u3068\u9060\u9694\u8ee2\u79fb\u306e\u91cd\u8981\u6027\u3092\u5168\u539f\u56e0\u6b7b\u4ea1\u306e<b>0.5\u500d<\/b>\u3001\u91cd\u7be4\u6709\u5bb3\u4e8b\u8c61\u3092<b>0.7\u500d<\/b>\u91cd\u8981\u8996\u3059\u308b\u3068\u3044\u3046\u4eee\u5b9a\u304b\u3089\u59cb\u3081\u3066\u307f\u307e\u3059\u3002<br \/>\n<br \/>\n&nbsp;<br \/>\n***\u3064\u3065\u304d\uff08step3\uff09<br \/>\n<br \/>\n&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u30b7\u30ca\u30ea\u30aa\u3067\u306f\u3001\u30b9\u30c6\u30c3\u30d7\uff11\u306b\u304a\u3044\u3066\u3001\u4f75\u5408\u3055\u308c\u308b\u91cd\u5927\u30a2\u30a6\u30c8\u30ab\u30e0\u3092\uff14\u3064\u6c7a\u5b9a\u3057\u307e\u3057\u305f\u3002 \u5404\u30a2\u30a6\u30c8\u30ab\u30e0\u306b\u95a2\u3059\u308b\u30a8\u30d3\u30c7\u30f3\u30b9\u3068\u305d\u306e\u78ba\u5b9f\u6027\u3092\u8981\u7d04\u3057\u305f\u3082\u306e\u304c\u4ee5\u4e0b\u3067\u3059\u3002 \u60a3\u80051000\u4eba\u3042\u305f\u308a\u306e\u7d76\u5bfe\u52b9\u679c\u63a8\u5b9a\u5024(95%CI)<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[5],"tags":[],"_links":{"self":[{"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/posts\/11683"}],"collection":[{"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=11683"}],"version-history":[{"count":51,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/posts\/11683\/revisions"}],"predecessor-version":[{"id":12047,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/posts\/11683\/revisions\/12047"}],"wp:attachment":[{"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=11683"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=11683"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=11683"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}