{"id":256,"date":"2013-01-29T14:46:49","date_gmt":"2013-01-29T05:46:49","guid":{"rendered":"http:\/\/aihara.la.coocan.jp\/blog\/?p=256"},"modified":"2014-04-16T15:30:58","modified_gmt":"2014-04-16T06:30:58","slug":"%e3%83%91%e3%83%a9%e3%82%b7%e3%83%a5%e3%83%bc%e3%83%88%e8%a3%85%e7%9d%80%e3%81%ae%e6%9c%89%e5%8a%b9%e6%80%a7%e3%81%ab%e9%96%a2%e3%81%99%e3%82%8brct%e3%81%af%e5%bf%85%e8%a6%81%e3%81%8b","status":"publish","type":"post","link":"http:\/\/aihara.la.coocan.jp\/?p=256","title":{"rendered":"\u30d1\u30e9\u30b7\u30e5\u30fc\u30c8\u88c5\u7740\u306e\u6709\u52b9\u6027\u306b\u95a2\u3059\u308bRCT\u306f\u5fc5\u8981\u304b"},"content":{"rendered":"<div>\n<p>EBM\u306b\u95a2\u3057\u3066\u6709\u540d\u306aBMJ\u30d1\u30e9\u30b7\u30e5\u30fc\u30c8\u8ad6\u6587\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u306e\u30d1\u30ed\u30c7\u30a3\u8ad6\u6587\u306f\u3001EBM\u305d\u306e\u3082\u306e\u3001\u3042\u308b\u3044\u306fRCT\u81f3\u4e0a\u4e3b\u7fa9\u306b\u5bfe\u3059\u308b\u6279\u5224\u306b\u4f7f\u308f\u308c\u3066\u3044\u308b\u3088\u3046\u3067\u3059\u304c\u3001EBM-working group\u3084GRADE working group\u306e\u8003\u3048\u306f\u7570\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n<p><\/p>\n<p><b>\u25a0BMJ\u8ad6\u6587<\/b><br \/>\n<a href=\"http:\/\/www.bmj.com\/content\/327\/7429\/1459\">Parachute use to prevent death and major trauma related to gravitational challenge: systematic review of randomised controlled trials.<\/a> BMJ Journal. 2003;327:1459<\/p>\n<p>\n<a href=\"http:\/\/aihara.la.coocan.jp\/parachute.php\" onclick=\"window.open('http:\/\/aihara.la.coocan.jp\/parachute.php','popup','width=540,height=457,scrollbars=no,resizable=no,toolbar=no,directories=no,location=no,menubar=no,status=no,left=0,top=0'); return false\" onkeypress=\"window.open('http:\/\/aihara.la.coocan.jp\/parachute.php','popup','width=540,height=457,scrollbars=no,resizable=no,toolbar=no,directories=no,location=no,menubar=no,status=no,left=0,top=0'); return false\"><img decoding=\"async\" loading=\"lazy\" src=\"http:\/\/aihara.la.coocan.jp\/parachute-thumb.jpg\" width=\"400\" height=\"338\" alt=\"parachute\" \/><\/a><br \/>\n<br clear=\"all\" \/><\/p>\n<p>BMJ\u8ad6\u6587\u306e\u5185\u5bb9\u306f\u6b21\u306e\u3088\u3046\u306a\u3082\u306e\u3067\u3059\u3002<\/p>\n<p><\/p>\n<p><b>\u9ad8\u6240\u304b\u3089\u306e\u843d\u4e0b\u306b\u95a2\u9023\u3057\u305f\u6b7b\u4ea1\u3084\u91cd\u7be4\u306a\u5916\u50b7\u3092\u9632\u6b62\u3059\u308b\u305f\u3081\u306e\u30d1\u30e9\u30b7\u30e5\u30fc\u30c8\u4f7f\u7528: <br \/>\n\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13\u306e\u30b7\u30b9\u30c6\u30de\u30c6\u30a3\u30c3\u30af\u30fb\u30ec\u30d3\u30e5\u30fc<\/b><\/p>\n<p><\/p>\n<p><b>\u25cf\u76ee\u7684\u3068\u65b9\u6cd5\uff1a<\/b><br \/>\n\u9ad8\u6240\u304b\u3089\u306e\u843d\u4e0b\u6642\u306e\u91cd\u7be4\u306a\u5916\u50b7\u3092\u9632\u6b62\u3059\u308b\u305f\u3081\u306b\u30d1\u30e9\u30b7\u30e5\u30fc\u30c8\u304c\u6709\u52b9\u304b\u3092\u8a55\u4fa1\u3059\u308b\u305f\u3081\u306b\u3001\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13\u306e\u30b7\u30b9\u30c6\u30de\u30c6\u30a3\u30c3\u30af\u30fb\u30ec\u30d3\u30e5\u30fc\u3092\u5b9f\u65bd\u3057\u305f\u3002<br \/>\n\u60c5\u5831\u6e90\u306f\u3001Medline, Web of Science, Embase\u3084\u30b3\u30af\u30e9\u30f3\u30e9\u30a4\u30d6\u30e9\u30ea\u3001\u9069\u5207\u306a\u30a4\u30f3\u30bf\u30fc\u30cd\u30c3\u30c8\u60c5\u5831\u30b5\u30a4\u30c8\u3068\u5f15\u7528\u30ea\u30b9\u30c8\u3002\u4e3b\u8981\u30a2\u30a6\u30c8\u30ab\u30e0\u306f\u3001\u6b7b\u4ea1\u3082\u3057\u304f\u306f\u91cd\u7be4\u306a\u5916\u50b7\uff08injury severity score &gt; 15\uff09\u3067\u3042\u3063\u305f\u3002<\/p>\n<p><\/p>\n<p>\n<b>\u25cf\u7d50\u679c\uff1a<\/b>\u30d1\u30e9\u30b7\u30e5\u30fc\u30c8\u4ecb\u5165\u306e\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13\u306f\u306a\u304b\u3063\u305f\u3002<br \/>\n<b>\u25cf\u8003\u5bdf\uff1a<\/b><br \/>\n<br \/>\u5065\u5eb7\u969c\u5bb3\u306e\u4e88\u9632\u3092\u610f\u56f3\u3057\u305f\u6570\u591a\u304f\u306e\u4ecb\u5165\u306b\u3064\u3044\u3066\u3082\u3044\u3048\u308b\u3053\u3068\u3060\u304c\u3001\u30d1\u30e9\u30b7\u30e5\u30fc\u30c8\u306e\u6709\u52b9\u6027\u306b\u3064\u3044\u3066\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13\u3092\u4f7f\u7528\u3057\u305f\u53b3\u683c\u306a\u8a55\u4fa1\u304c\u306a\u3055\u308c\u3066\u3044\u306a\u3044\u3002EBM\u306e\u64c1\u8b77\u8005\u306f\u3001\u89b3\u5bdf\u7814\u7a76\u306e\u30c7\u30fc\u30bf\u306e\u307f\u3092\u4f7f\u3063\u3066\u8a55\u4fa1\u3055\u308c\u305f\u4ecb\u5165\u306e\u63a1\u629e\u3092\u6279\u5224\u3057\u3066\u304d\u305f\u3002\u6700\u3082\u6025\u9032\u7684\u306aEBM\u80af\u5b9a\u6d3e\u8ad6\u8005\u304c\u30d1\u30e9\u30b7\u30e5\u30fc\u30c8\u306e\u4e8c\u91cd\u76f2\u691c\u30e9\u30f3\u30c0\u30e0\u5316\u30d7\u30e9\u30bb\u30dc\u5bfe\u7167\u30af\u30ed\u30b9\u30aa\u30fc\u30d0\u30fc\u8a66\u9a13\u3092\u4f01\u753b\u3057\u3001\u3053\u308c\u306b\u53c2\u52a0\u3059\u308c\u3070\u3001\u8ab0\u3082\u304c\u30e1\u30ea\u30c3\u30c8\u3092\u4eab\u53d7\u3067\u304d\u308b\u3060\u308d\u3046\u3002<\/p>\n<p><\/p>\n<p><b>\u25a0\u540c\u3058\u30c6\u30fc\u30de\u306b\u95a2\u3057\u3066\u3001EBM-, GRADE working group\u306e\u8003\u3048\u65b9\u306f\u6b21\u306e\u3088\u3046\u306a\u3082\u306e\u3067\u3059\u3002<\/b><\/p>\n<table summary=\"parachute\">\n<tr>\n<td valign=\"top\">\n<a href=\"http:\/\/aihara.la.coocan.jp\/parachute-21.php\" onclick=\"window.open('http:\/\/aihara.la.coocan.jp\/parachute-21.php','popup','width=658,height=529,scrollbars=no,resizable=no,toolbar=no,directories=no,location=no,menubar=no,status=no,left=0,top=0'); return false\" onkeypress=\"window.open('http:\/\/aihara.la.coocan.jp\/parachute-21.php','popup','width=658,height=529,scrollbars=no,resizable=no,toolbar=no,directories=no,location=no,menubar=no,status=no,left=0,top=0'); return false\"><img decoding=\"async\" loading=\"lazy\" src=\"http:\/\/aihara.la.coocan.jp\/parachute-2-thumb.jpg\" width=\"400\" height=\"321\" alt=\"parachute2\" \/><\/a><\/td>\n<td valign=\"top\">\n\uff08\u56f3\u306f\u3001Holger Schunemann\u6559\u6388\u3088\u308a\uff09<\/td>\n<\/tr>\n<\/table>\n<p><br clear=\"all\" \/><\/p>\n<p>Not thinking about effect sizes separately (and thus basing your &#8220;level of evidence&#8221; solely on study design) is wrong. When effect sizes are large (or extremely large, as in the parachute example), conduction RCTs are not necessary.<br \/>\n<span style=\"color:#ff0000;\">\u52b9\u679c\u306e\u5927\u304d\u3055\u3092\u5225\u306b\u8003\u3048\u306a\u3044\uff08\u305d\u3057\u3066\u3001\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u30ec\u30d9\u30eb\u3092\u7814\u7a76\u30c7\u30b6\u30a4\u30f3\u3060\u3051\u3067\u6c7a\u5b9a\u3059\u308b\uff09\u3053\u3068\u306f\u3001\u9593\u9055\u3063\u3066\u3044\u308b\u3002\u52b9\u679c\u30b5\u30a4\u30ba\u304c\u5927\u304d\u3044\uff08\u3082\u3057\u304f\u306f\u3001\u30d1\u30e9\u30b7\u30e5\u30fc\u30c8\u4f8b\u306e\u3088\u3046\u306b\u6975\u3081\u3066\u5927\u304d\u3044\uff09\u306a\u3089\u3070\u3001RCT\u306e\u5b9f\u65bd\u306f\u5fc5\u8981\u306a\u3044\u3002<\/span><br \/>\n<b>GRADE\u30a2\u30d7\u30ed\u30fc\u30c1\u306b\u3088\u308b\u8a55\u4fa1\u306f\u3001\u89b3\u5bdf\u7814\u7a76\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u8cea \uff08low\uff09\u3092rate-up\u3059\u308b\uff08 high\uff09\u3002<\/b><\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>EBM\u306b\u95a2\u3057\u3066\u6709\u540d\u306aBMJ\u30d1\u30e9\u30b7\u30e5\u30fc\u30c8\u8ad6\u6587\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u306e\u30d1\u30ed\u30c7\u30a3\u8ad6\u6587\u306f\u3001EBM\u305d\u306e\u3082\u306e\u3001\u3042\u308b\u3044\u306fRCT\u81f3\u4e0a\u4e3b\u7fa9\u306b\u5bfe\u3059\u308b\u6279\u5224\u306b\u4f7f\u308f\u308c\u3066\u3044\u308b\u3088\u3046\u3067\u3059\u304c\u3001EBM-working group\u3084GRADE working gro [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[3],"tags":[51,352,62,351],"_links":{"self":[{"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/posts\/256"}],"collection":[{"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=256"}],"version-history":[{"count":1,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/posts\/256\/revisions"}],"predecessor-version":[{"id":426,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/posts\/256\/revisions\/426"}],"wp:attachment":[{"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=256"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=256"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=256"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}