{"id":3464,"date":"2015-12-16T11:09:26","date_gmt":"2015-12-16T02:09:26","guid":{"rendered":"http:\/\/aihara.la.coocan.jp\/?p=3464"},"modified":"2015-12-16T11:09:26","modified_gmt":"2015-12-16T02:09:26","slug":"%e3%83%a1%e3%82%bf%e3%82%a2%e3%83%8a%e3%83%aa%e3%82%b7%e3%82%b9%ef%bc%9a%e7%95%b0%e3%81%aa%e3%82%8b%e5%b0%ba%e5%ba%a6%e3%82%92%e4%bd%bf%e3%81%a3%e3%81%9f%e9%80%a3%e7%b6%9a%e5%a4%89%e6%95%b0%e3%81%ae","status":"publish","type":"post","link":"http:\/\/aihara.la.coocan.jp\/?p=3464","title":{"rendered":"\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\uff1a\u7570\u306a\u308b\u5c3a\u5ea6\u3092\u4f7f\u3063\u305f\u9023\u7d9a\u5909\u6570\u306e\u52b9\u679c\u30b5\u30a4\u30ba\u306e\uff15\u3064\u306e\u8868\u793a\u6cd5"},"content":{"rendered":"

\u7814\u7a76\u306e\u6700\u5f8c\u306b\uff11\u5ea6\u3060\u3051\u6e2c\u5b9a\u3055\u308c\u308b\uff12\u5024\u30a2\u30a6\u30c8\u30ab\u30e0\u3068\u9055\u3044\u3001\u9023\u7d9a\u5909\u6570<\/strong>\u306f\u7814\u7a76\u306e\u958b\u59cb\uff08\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u3001\u3064\u307e\u308a\u89b3\u5bdf\u958b\u59cb\u524d\u307e\u305f\u306f\u4ecb\u5165\u5b9f\u65bd\u524d\uff09\u3068\u7d42\u4e86\u306e\u4e21\u65b9\u306e\u6642\u70b9\u3067\u6e2c\u5b9a\u3055\u308c\u307e\u3059\u3002\u3057\u305f\u304c\u3063\u3066\u3001\u9023\u7d9a\u30a2\u30a6\u30c8\u30ab\u30e0<\/strong>\u306f\u7814\u7a76\u306e\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u304b\u3089\u7d42\u4e86\u6642\u306b\u304b\u3051\u3066\u306e\u30b9\u30b3\u30a2\u306e\u5909\u5316\uff08\u3059\u306a\u308f\u3061\u3001\u5909\u5316\u30b9\u30b3\u30a2\uff09\u307e\u305f\u306f\u7814\u7a76\u306e\u7d42\u4e86\u6642\u306b\u304a\u3051\u308b\u6700\u7d42\u6e2c\u5b9a\u5024\uff08\u3059\u306a\u308f\u3061\u3001\u6700\u7d42\u5024\uff09\u3068\u3057\u3066\u8868\u73fe\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u3053\u306e\u5834\u5408\u3001\u60f3\u5b9a\u30ea\u30b9\u30af\uff08\u30b9\u30b3\u30a2\uff09\u3068\u306f\u3001\u5bfe\u7167\u7fa4\u306b\u304a\u3051\u308b\u6700\u7d42\u5024\u307e\u305f\u306f\u5909\u5316\u30b9\u30b3\u30a2\u306e\u3053\u3068\u3092\u6307\u3057\u307e\u3059\u3002\u9023\u7d9a\u30a2\u30a6\u30c8\u30ab\u30e0\u306e\u305f\u3081\u306e\uff12\u3064\u306e\u91cd\u8981\u306a\u7d71\u5408\u52b9\u679c\u63a8\u5b9a\u5024\u304c\u3001\u5e73\u5747\u5dee\uff08MD\uff09\u307e\u305f\u306f\u6a19\u6e96\u5316\u5e73\u5747\u5dee\uff08SMD\uff09\u3067\u3059\u3002<\/p>\n

\u30b7\u30b9\u30c6\u30de\u30c6\u30a3\u30c3\u30af\u30ec\u30d3\u30e5\u30fc\u306b\u304a\u3044\u3066\u306f\u3001\u3057\u3070\u3057\u3070\u7570\u306a\u308b\u5c3a\u5ea6\u3092\u4f7f\u3063\u305f\u6e2c\u5b9a\u6cd5\u306b\u3088\u308a\u9023\u7d9a\u5909\u6570\u306e\u7814\u7a76\u3092\u6271\u3046\u5834\u5408\u304c\u3042\u308a\u307e\u3059\u3002\u8907\u6570\u306e\u7814\u7a76\u306b\u304a\u3044\u3066\u3001\u540c\u4e00\u306e\u69cb\u6210\u8981\u7d20\u306e\u6e2c\u5b9a\u306b\u7570\u306a\u308b\u30c4\u30fc\u30eb\u304c\u4f7f\u308f\u308c\u3066\u3044\u308b\u5834\u5408\u306f\u3001\u9023\u7d9a\u30c7\u30fc\u30bf\u3092\u7d71\u5408\u3059\u308b\u305f\u3081\u306e\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u306b\u304a\u3044\u3066\u306f\u3001SMD\u3092\u5229\u7528\u3059\u308b\u3053\u3068\u304c\u3088\u3044\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u3057\u304b\u3057\u3001JCE GRADE\u30b7\u30ea\u30fc\u30ba\u306b\u304a\u3044\u3066\u306f\u3001\u9023\u7d9a\u30a2\u30a6\u30c8\u30ab\u30e0\u306b\u95a2\u3059\u308bbody of evidence\u306e\u8cea\u8a55\u4fa1\u306e\u969b\uff08\u7279\u306b\u7570\u306a\u308b\u5c3a\u5ea6\u3092\u4f7f\u3063\u305f\u9023\u7d9a\u5909\u6570\u306e\u52b9\u679c\u30b5\u30a4\u30ba\u3092\u6271\u3046\u969b\uff09\u3001\uff15\u3064\u306e\u8868\u793a\u6cd5<\/strong>\u3092\u89e3\u8aac\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n

<\/p>\n

\u25cfFive approaches to presenting results of continuous variables when primary studies have used different instruments to measure the same construct<\/b><\/p>\n

\n

GRADE guidelines 13. Preparing Summary of Findings tables and evidence profilesdcontinuous outcomes.
J Clin Epidemiol<\/a>. 2013 Feb;66(2):173-83<\/p>\n<\/div>\n\n\n\n\n\n\n\n
Approach<\/b><\/td>\nAdvantages<\/b><\/td>\nDisadvantages<\/b><\/td>\nRecommendation<\/b><\/td>\n<\/tr>\n
SD units (standardized mean difference; effect size)<\/b><\/td>\nWidely used<\/td>\nInterpretation challenging
\nCan be misleading depending on whether population is very homogenous or heterogeneous<\/td>\n		Do not use as the only approach<\/td>\n<\/tr>\n
Present as natural units<\/b><\/td>\nMay be viewed as closer to primary data<\/td>\nFew instruments sufficiently used in clinical practice to make units easily interpretable<\/td>\nApproaches to conversion to natural units include those based on SD units and rescaling approaches. We suggest the latter. In rare situations when instrument very familiar to frontline clinicians, seriously consider this presentation<\/td>\n<\/tr>\n
Relative and absolute effects<\/b><\/td>\nVery familiar to clinical audiences and thus facilitate understanding
\nCan apply GRADE guidance for large and very large effects\n<\/td>\n		Involve assumptions that may be questionable (particularly methods based on SD units)\n<\/td>\nIf the MID is known, use this strategy in preference to relying on SD units
\nAlways seriously consider this option<\/td>\n<\/tr>\n
Ratio of means<\/b><\/td>\nMay be easily interpretable to clinical audiences Involves fewer questionable assumptions than some other approaches
\nCan apply GRADE guidance for large and very large effects<\/td>\n		Cannot be applied when measure is change and therefore negative values possible
\nInterpretation requires knowledge and interpretation of control group mean<\/td>\n		Consider as complementing other approaches, particularly the presentation of relative and absolute effects<\/td>\n<\/tr>\n
MID units<\/b><\/td>\nMay be easily interpretable to audiences
\nNot vulnerable to population heterogeneity\n<\/td>\n		Only applicable when MID is known
\nTo the extent that MID is uncertain, this approach will be less attractive (*)<\/td>\n		Consider as complementing other approaches, particularly the presentation of relative and absolute effects<\/td>\n<\/tr>\n<\/table>\n
\n

*:Abbreviations: SD, standard deviation; MID, minimally important difference.<\/p>\n

<\/p>\n

MID\u304c\u4e0d\u660e\u306e\u7814\u7a76\u304c\u7d44\u307f\u5165\u308c\u3089\u308c\u3066\u3044\u3066\u3082\u3001MID\u65e2\u77e5\u306e\u4ed6\u306e\u7814\u7a76\u306eSD\u3092\u53c2\u8003\u306b\u3057\u3066\u3001\u7d71\u5408\u89e3\u6790\u51e6\u7406\u304c\u53ef\u80fd\u3068\u3044\u3046\u305d\u306e\u5f8c\u306e\u5831\u544a\uff08Johnston BC. et al: JCE 2012; 65 817-26<\/a>\uff09\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n<\/div>\n

\u3053\u308c\u3089\u306e\uff15\u3064\u306e\u30a2\u30d7\u30ed\u30fc\u30c1\u306f\u3001\u30b7\u30b9\u30c6\u30de\u30c6\u30a3\u30c3\u30af\u30ec\u30d3\u30e5\u30fc\u3084\u8a3a\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u306b\u304a\u3051\u308b\u9023\u7d9a\u30a2\u30a6\u30c8\u30ab\u30e0\u306b\u95a2\u3059\u308b\u52b9\u679c\u30b5\u30a4\u30ba\u306e\u7cbe\u78ba\u3055\u3092\u8003\u3048\u308b\u4e0a\u3067\u91cd\u8981\u3067\u3059\u304c\u3001\u73fe\u72b6\u306eGRADEpro\/GDT<\/strong>\u306f\u3059\u3079\u3066\u306b\u5bfe\u5fdc\u3057\u3066\u306f\u3044\u307e\u305b\u3093\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

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