{"id":5273,"date":"2016-09-01T09:21:59","date_gmt":"2016-09-01T00:21:59","guid":{"rendered":"http:\/\/aihara.la.coocan.jp\/?p=5273"},"modified":"2016-09-20T09:30:08","modified_gmt":"2016-09-20T00:30:08","slug":"grade-cpg%e4%bd%9c%e6%88%90%e3%81%ae%e5%9f%ba%e6%9c%ac%e3%83%bc%ef%bc%93%ef%bc%8e%ef%bc%91%ef%bc%98sr%e3%82%a8%e3%83%93%e3%83%87%e3%83%b3%e3%82%b9%e3%81%ae%e7%a2%ba%e5%ae%9f%e6%80%a7-%e2%91%a5","status":"publish","type":"post","link":"http:\/\/aihara.la.coocan.jp\/?p=5273","title":{"rendered":"GRADE CPG\u4f5c\u6210\u306e\u57fa\u672c\u30fc\uff13\uff0e\uff11\uff18:[SR]\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u78ba\u5b9f\u6027-\u2465\uff1aImprecision-(3)\/\u9010\u6b21\u89e3\u6790"},"content":{"rendered":"<p>[GRADE-CPG\u89e3\u8aac\u8cc7\u6599-24]<\/p>\n<p><a href=\"http:\/\/aihara.la.coocan.jp\/?p=3920\">http:\/\/aihara.la.coocan.jp\/?p=3920<\/a>\u3067\u7d39\u4ecb\u3057\u305f<b>Trial Sequential Analysis\uff08\u9010\u6b21\u89e3\u6790\uff09<\/b>\u3092\u4f7f\u3063\u3066\u3001\u30c8\u30ea\u30d7\u30ebX\u306b\u95a2\u3059\u308b\u30a2\u30a6\u30c8\u30ab\u30e0\u306e\u3044\u304f\u3064\u304b\u3092\u7d71\u8a08\u5b66\u7684\u306b\u8abf\u3079\u3066\u307f\u307e\u3059\u3002<br \/>\n\u975eGRADE\u306e\u7d71\u8a08\u5b66\u8005\u306f\u3001\u304a\u305d\u3089\u304f\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u89e3\u6790\u3092\u3059\u308b\u3053\u3068\u3067\u3057\u3087\u3046\u3057\u3001\u3082\u3061\u308d\u3093\u3053\u308c\u3082\u9593\u9055\u3044\u3067\u306f\u306a\u3044\u3067\u3059\u3057\u3001\u5f53\u7136\u306a\u304c\u3089\u3001\u5bfe\u7167\u7fa4\u306e\u30a4\u30d9\u30f3\u30c8\u767a\u751f\u7387\u306e\u9055\u3044\u304b\u3089OIS\u306b\u95a2\u3059\u308b\u7d50\u679c\u3082\u3084\u3084\u7570\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u5229\u7528\u3059\u308b\u7d71\u8a08\u30bd\u30d5\u30c8\u306f\u3001STATA \uff08\u30b3\u30de\u30f3\u30c9metacumbounds\uff09\u3068R\uff08\u30d1\u30c3\u30b1\u30fc\u30b8foreign, ldbounds\uff09\u3067\u3059\u3002<\/p>\n<p><\/p>\n<p><b>\u25a0\u30a2\u30a6\u30c8\u30ab\u30e0\uff1a\u5fc3\u7b4b\u6897\u585e<\/b><\/p>\n<p>\u7d50\u679c\uff1aZ\u66f2\u7dda\u306f\u60c5\u5831\u91cf\uff08information size\uff09\u306b\u9054\u3059\u308b\u524d\u306bmonitoring boundary\uff08\u8d64\u7dda\uff09\u3068\u4ea4\u5dee\u3057\u3066\u304a\u308a\u3001\u52b9\u679c\u306b\u78ba\u56fa\u305f\u308b\u30a8\u30d3\u30c7\u30f3\u30b9\u3092\u63d0\u4f9b\u3057\u3066\u3044\u308b\uff08\u771f\u967d\u6027\uff09<\/p>\n<p><a href=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2016\/08\/tsa-mi.png\"><img decoding=\"async\" src=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2016\/08\/tsa-mi.png\" alt=\"tsa-mi\" width=\"85%\" class=\"aligncenter size-full wp-image-5519\" srcset=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2016\/08\/tsa-mi.png 664w, http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2016\/08\/tsa-mi-300x209.png 300w\" sizes=\"(max-width: 664px) 100vw, 664px\" \/><\/a><\/p>\n<div align=\"right\">\n<p>APIS: Information size calculated from an a priori assumed intervention effect<\/p>\n<\/div>\n<p><\/p>\n<p><b>\u25a0\u30a2\u30a6\u30c8\u30ab\u30e0\uff1a\u30c7\u30a3\u30b9\u30da\u30d7\u30b7\u30a2<\/b><\/p>\n<p>\u7d50\u679c\uff1aZ\u66f2\u7dda\u306fZ=1.96\u306e\u6a2a\u70b9\u7dda\u3068\u4ea4\u5dee\u3057\u6709\u610f\u306a\u7d50\u679c\u3067\u3042\u308b\u304c\u3001monitoring boundary\uff08\u8d64\u7dda\uff09\u3068\u4ea4\u5dee\u3057\u3066\u3044\u306a\u3044\u305f\u3081\u507d\u308a\u306e\u52b9\u679c\u3067\u3042\u308b\uff08\u507d\u967d\u6027\uff09<br \/>\nTSA\u306b\u304a\u3044\u3066\u306f\u3001\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u30a4\u30d9\u30f3\u30c8\u7387\u3092\u5bfe\u7167\u7fa4\u306e[\u7dcf\u30a4\u30d9\u30f3\u30c8\u6570\/\u7dcf\u6570]\u304b\u3089\u7b97\u51fa\u3057\u3066\u3044\u307e\u3059\u3002\u30a4\u30d9\u30f3\u30c8\u767a\u751f\u7387\u304c\u5c11\u306a\u3044\u5834\u5408\u306eOIS\u306b\u95a2\u3059\u308b\u8003\u3048\u306fGRADE2\u7248\u3092\u53c2\u7167\u304f\u3060\u3055\u3044\u3002<\/p>\n<p><a href=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2016\/08\/tsa-fd.png\"><img decoding=\"async\" src=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2016\/08\/tsa-fd.png\" alt=\"tsa-fd\" width=\"85%\" class=\"aligncenter size-full wp-image-5521\" srcset=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2016\/08\/tsa-fd.png 663w, http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2016\/08\/tsa-fd-300x215.png 300w\" sizes=\"(max-width: 663px) 100vw, 663px\" \/><\/a><br \/>\n<\/p>\n<p><b>\u25a0\u30a2\u30a6\u30c8\u30ab\u30e0\uff1a\u7dcf\u6b7b\u4ea1<\/b><\/p>\n<p>\u7d50\u679c\uff1a\u5fc5\u8981\u60c5\u5831\u91cf\u3092\u6e80\u305f\u3057\u3066\u3044\u308b\u306b\u3082\u304b\u304b\u308f\u3089\u305a\u3001\u4e8b\u524d\u306b\u8a2d\u5b9a\u3057\u305f\u52b9\u679c\u306f\u306a\u3044\uff08\u771f\u9670\u6027\uff09<\/p>\n<p><a href=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2016\/08\/tsa-mortality.png\"><img decoding=\"async\" src=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2016\/08\/tsa-mortality.png\" alt=\"tsa-mortality\" width=\"85%\" class=\"aligncenter size-full wp-image-5516\" srcset=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2016\/08\/tsa-mortality.png 654w, http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2016\/08\/tsa-mortality-300x217.png 300w\" sizes=\"(max-width: 654px) 100vw, 654px\" \/><\/a><br \/>\n<\/p>\n<p><b>\u25a0\u30a2\u30a6\u30c8\u30ab\u30e0\uff1a\u8133\u5352\u4e2d<\/b><\/p>\n<p>\u7d50\u679c\uff1aZ\u66f2\u7dda\u306fZ=1.96\u306e\u6a2a\u70b9\u7dda\u3068\u4ea4\u5dee\u3057\u3066\u304a\u3089\u305a\u3001\u30a8\u30d3\u30c7\u30f3\u30b9\u304c\u6b20\u5982\u3057\u3066\u3044\u308b\u3053\u3068\u3092\u793a\u3059\u3002\u3059\u306a\u308f\u3061\u3001\u5f53\u8a72\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u306f\u3001\u5fc5\u8981\u60c5\u5831\u91cf\u3088\u308a\u60a3\u8005\u304c\u5c11\u306a\u3044\uff08\u507d\u9670\u6027\uff09<\/p>\n<p><a href=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2016\/08\/tsa-stroke.png\"><img decoding=\"async\" src=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2016\/08\/tsa-stroke.png\" alt=\"tsa-stroke\" width=\"85%\" class=\"aligncenter size-full wp-image-5522\" srcset=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2016\/08\/tsa-stroke.png 660w, http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2016\/08\/tsa-stroke-300x214.png 300w\" sizes=\"(max-width: 660px) 100vw, 660px\" \/><\/a><br \/>\n<\/p>\n<p><b>\u25a0\u30a2\u30a6\u30c8\u30ab\u30e0\uff1a\u5c0f\u51fa\u8840<\/b><\/p>\n<p>\u7d50\u679c\uff1aZ\u66f2\u7dda\u306fZ=1.96\u306e\u6a2a\u70b9\u7dda\u3068\u4ea4\u5dee\u3057\u6709\u610f\u306a\u7d50\u679c\u3067\u3042\u308b\u304c\u3001monitoring boundary\uff08\u8d64\u7dda\uff09\u3068\u4ea4\u5dee\u3057\u3066\u3044\u306a\u3044\u305f\u3081\u507d\u308a\u306e\u52b9\u679c\u3067\u3042\u308b\uff08\u507d\u967d\u6027\u3001\u56f3a\uff09\u3002\u307e\u305f\u3001AIS\u3092\u307f\u308b\u3053\u3068\u3067\u3001\u691c\u51fa\u529b\u304c\u4f4e\u3044\u3053\u3068\uff08power=24%\uff09\u304c\u308f\u304b\u308b\uff08\u56f3b\uff09\u3002<\/p>\n<p>\u56f3a<\/p>\n<p><a href=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2016\/08\/tsa-minor_bleeding-1.png\"><img decoding=\"async\" src=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2016\/08\/tsa-minor_bleeding-1.png\" alt=\"tsa-minor_bleeding-1\" width=\"85%\" class=\"aligncenter size-full wp-image-5529\" srcset=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2016\/08\/tsa-minor_bleeding-1.png 649w, http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2016\/08\/tsa-minor_bleeding-1-300x214.png 300w\" sizes=\"(max-width: 649px) 100vw, 649px\" \/><\/a><\/p>\n<p>\u56f3b<\/p>\n<p><a href=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2016\/08\/tsa-minor_bleeding-2.png\"><img decoding=\"async\" src=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-\ncontent\/uploads\/2016\/08\/tsa-minor_bleeding-2.png\" alt=\"tsa-minor_bleeding-2\" width=\"85%\" class=\"aligncenter size-full wp-image-5530\" srcset=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2016\/08\/tsa-minor_bleeding-2.png 657w, http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2016\/08\/tsa-minor_bleeding-2-300x220.png 300w\" sizes=\"(max-width: 657px) 100vw, 657px\" \/><\/a><\/p>\n<div align=\"right\">\n<p>AIS:Accrued information size (=N), the total number of participants in the meta-analysis.<\/p>\n<\/div>\n<p>\n&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>[GRADE-CPG\u89e3\u8aac\u8cc7\u6599-24] http:\/\/aihara.la.coocan.jp\/?p=3920\u3067\u7d39\u4ecb\u3057\u305fTrial Sequential Analysis\uff08\u9010\u6b21\u89e3\u6790\uff09\u3092\u4f7f\u3063\u3066\u3001\u30c8\u30ea\u30d7\u30ebX\u306b\u95a2\u3059\u308b\u30a2\u30a6\u30c8\u30ab\u30e0\u306e\u3044 [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[455,5,291],"tags":[],"_links":{"self":[{"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/posts\/5273"}],"collection":[{"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=5273"}],"version-history":[{"count":38,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/posts\/5273\/revisions"}],"predecessor-version":[{"id":5834,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/posts\/5273\/revisions\/5834"}],"wp:attachment":[{"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=5273"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=5273"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=5273"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}