{"id":6336,"date":"2016-12-09T17:24:43","date_gmt":"2016-12-09T08:24:43","guid":{"rendered":"http:\/\/aihara.la.coocan.jp\/?p=6336"},"modified":"2016-12-16T14:35:10","modified_gmt":"2016-12-16T05:35:10","slug":"grade-%ef%bd%83%ef%bd%90%ef%bd%87%e3%81%ae%e5%9f%ba%e6%9c%ac%e3%83%bc%ef%bc%94%ef%bc%8e5%ef%bc%9acpg%e3%82%a8%e3%83%93%e3%83%87%e3%83%b3%e3%82%b9%e3%81%8b%e3%82%89%e6%8e%a8%e5%a5%a8%e3%81%b8","status":"publish","type":"post","link":"http:\/\/aihara.la.coocan.jp\/?p=6336","title":{"rendered":"GRADE \uff23\uff30\uff27\u306e\u57fa\u672c\u30fc\uff14\uff0e5\uff1a[CPG]\u30a8\u30d3\u30c7\u30f3\u30b9\u304b\u3089\u63a8\u5968\u3078\u2464\uff1a\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u30ea\u30b9\u30af\u306e\u60f3\u5b9a(1)-\u4e88\u5f8cGRADE\u306e\u6d3b\u7528"},"content":{"rendered":"<p>[GRADE-CPG\u89e3\u8aac\u8cc7\u6599-33]<\/p>\n<p>\u3000<\/p>\n<p>GRADE\u306b\u5f93\u3063\u305f\u8a3a\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u4f5c\u6210\u306b\u304a\u3044\u3066\u306f\u3001SR\u30c1\u30fc\u30e0\u3068CPG\u30d1\u30cd\u30eb\u306e\u5354\u8abf\u304c\u5fc5\u8981\u3067\u3059\u304c\u3001\u4e21\u8005\u306b\u306f\u30a2\u30a6\u30c8\u30ab\u30e0\u306b\u5bfe\u3059\u308b\u8003\u3048\u65b9\u306e\u76f8\u9055\u304c\u3042\u308a\u307e\u3059\u3002\u305d\u3057\u3066\u3001\u63a8\u5968\u4f5c\u6210\u3092\u76ee\u7684\u3068\u3057\u305fCPG\u30d1\u30cd\u30eb\u306b\u306f\u3001\u3044\u304f\u3064\u304b\u306e\u91cd\u8981\u306a\u4e8b\u524d\u4f5c\u696d\u304c\u3042\u308a\u3001\u6c7a\u3057\u3066\u300c\u3068\u308a\u3042\u3048\u305a\u30a8\u30d3\u30c7\u30f3\u30b9\u7dcf\u4f53\u3092\u307f\u306a\u304c\u3089\u63a8\u5968\u306e\u5f37\u3055\u3092\u691c\u8a0e\u3057\u307e\u3057\u3087\u3046\u300d\u3068\u3057\u3066\u306f\u3044\u3051\u307e\u305b\u3093\u3002\u305d\u306e\u3088\u3046\u306a\u3053\u3068\u3092\u3059\u308b\u3068\u3001\u63a8\u5968\u306e\u5f37\u3055\u3084\u65b9\u5411\u304c\u3001\u9014\u4e2d\u3067\u4f55\u5ea6\u3082\u5909\u308f\u3063\u3066\u3057\u307e\u3046\u3053\u3068\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n<p><\/p>\n<table summary=\"baselinerisk1\" border=\"1\" style=\"border-collapse:collapse;border:none;\">\n<tr>\n<td style=\"border:1px solid #000000; padding:5px; background:#FFEFD5;\">\n<p><b>\u25cfSR\u30c1\u30fc\u30e0\u3068CPG\u30d1\u30cd\u30eb\u306e\u30a2\u30a6\u30c8\u30ab\u30e0\u306b\u95a2\u3059\u308b\u8003\u3048\u65b9\u306e\u9055\u3044<\/b><\/P><\/tr>\n<tr>\n<td style=\"border:1px solid #000000; padding:5px;background:#ffffff;\">\n<p>CQ\u306e\u30a2\u30a6\u30c8\u30ab\u30e0\u8a2d\u5b9a\u6642\u306b\u306f\u3001\uff08\u4e00\u822c\u306bSR\u30c1\u30fc\u30e0\u304c\uff09\u91cd\u8981\u3068\u91cd\u5927\u306a\u30a2\u30a6\u30c8\u30ab\u30e0\u3092\u9078\u51fa\u3059\u3079\u304f\u3001\uff11\uff5e\uff19\u70b9\u30b9\u30b1\u30fc\u30eb\u3067\u8a55\u4fa1\u3057\u307e\u3059\u3002SR\u30c1\u30fc\u30e0\u304c\u9078\u51fa\u3057\u305f\u30a2\u30a6\u30c8\u30ab\u30e0\u306b\u3064\u3044\u3066\u3001\u8a3a\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3067\u63a1\u7528\u3059\u308b\u304b\u3069\u3046\u304b\u306f\u3001CPG\u30d1\u30cd\u30eb\u306e\u6c7a\u65ad\u306b\u59d4\u306d\u308b\u3053\u3068\u304c\u901a\u5e38\u3067\u3059\uff08SR\u30c1\u30fc\u30e0\u3068CPG\u30d1\u30cd\u30eb\u304c\u4e00\u7dd2\u306b\u8b70\u8ad6\u3057\u3066\u6c7a\u5b9a\u3059\u308b\u3053\u3068\u3082\u3042\u308b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u304c\u3001\u63a8\u5968\u3092\u6c7a\u5b9a\u3059\u308b\u305f\u3081\u306e\u30a2\u30a6\u30c8\u30ab\u30e0\u306e\u9078\u51fa\u306f\u3001\u57fa\u672c\u7684\u306b\u306f\u3001SR\u30c1\u30fc\u30e0\u306e\u80fd\u529b\u5916\u3060\u308d\u3046\u3057\u3001\u305d\u3053\u307e\u3067SR\u30c1\u30fc\u30e0\u306b\u8ca0\u62c5\u3092\u5f37\u3044\u308b\u3053\u3068\u306f\u3067\u304d\u306a\u3044\u3068\u3044\u3046\u8003\u3048\u3067\u3059\uff09\u3002<\/p>\n<p>\u3064\u307e\u308a\u3001\u201cCQ\u306e\u30a2\u30a6\u30c8\u30ab\u30e0\u8a2d\u5b9a\u6642\u201d\u306e\u91cd\u8981\u5ea6\u306e\u30b9\u30b3\u30a2\u306fSR\u306e\u5bfe\u8c61\u306b\u3059\u308b\u304b\u3069\u3046\u304b\u3092\u8003\u616e\u3059\u308b\u3082\u306e\u3067\u3059\u304c\u3001\u53b3\u5bc6\u306b\u306f\u3001\u201c\u91cd\u8981\u3067\u306f\u306a\u3044\uff08\uff11\uff5e\uff13\u70b9\uff09\u201d vs \u201c\u91cd\u8981\u30fb\u91cd\u5927\uff08\uff14\uff5e\uff19\u70b9\uff09\u201d\u306e\u30a2\u30a6\u30c8\u30ab\u30e0\u3068\u9078\u5225\u3068\u3082\u3044\u3048\u307e\u3059\u3002<\/P><\/td>\n<\/tr>\n<\/table>\n<p><\/p>\n<p>\u3055\u3066\u3001\u518d\u691c\u8a0e\u306e\u4e0a\u3067\u6c7a\u5b9a\u3057\u305f\u201c\u91cd\u5927\u306a\u30a2\u30a6\u30c8\u30ab\u30e0\u201d\u306b\u95a2\u3057\u3066\u3001\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u78ba\u5b9f\u6027\u3092\u8a55\u4fa1\u3057\u63a8\u5968\u6c7a\u5b9a\u30d7\u30ed\u30bb\u30b9\u306b\u9032\u3080\u524d\u306b\u3001CPG\u30d1\u30cd\u30eb\u306b\u306f\u3044\u304f\u3064\u304b\u306e\u91cd\u8981\u306a\u4e8b\u524d\u691c\u8a0e\u304c\u3042\u308a\u3001\u305d\u306e\u4e00\u3064\u304c<strong>\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u30ea\u30b9\u30af\u306e\u60f3\u5b9a<\/strong>\u3067\u3059\u3002\u3053\u308c\u3082SR\u30c1\u30fc\u30e0\u306e\u7ba1\u8f44\u5916\u3067\u3042\u308a\u3001CPG\u30d1\u30cd\u30eb\u304c\u5b9f\u65bd\u3059\u308b\u3053\u3068\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n<p><\/p>\n<table summary=\"baselinerisk2\" border=\"1\" style=\"border-collapse:collapse;border:none;\">\n<tr>\n<td style=\"border:1px solid #000000; padding:5px; background:#FFEFD5;\">\n<p><b>\u25cf\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u30ea\u30b9\u30af\u306e\u60f3\u5b9a\u304c\u306a\u305c\u5fc5\u8981\u306a\u306e\u304b\uff1f<\/b><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td style=\"border:1px solid #000000; padding:5px;background:#ffffff;\">\n<p>SR\u30c1\u30fc\u30e0\u306f\u3001\u8a2d\u5b9a\u3057\u305fCQ\u306b\u304a\u3051\u308bPICO\u3092\u4f7f\u3063\u3066\u3001\u5e45\u5e83\u304f\u304b\u3064\u7db2\u7f85\u7684\u306b\u30a8\u30d3\u30c7\u30f3\u30b9\u3092\u53ce\u96c6\u3057\u3066\u3001\u9069\u683c\u57fa\u6e96\u306b\u307f\u3042\u3063\u305f\u7814\u7a76\u30a8\u30d3\u30c7\u30f3\u30b9\u3092\u7d71\u5408\u3057\u307e\u3059\u304c\u3001\u5404\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u30ea\u30b9\u30af\u306f\u3070\u3089\u3064\u3044\u3066\u3044\u308b\u3053\u3068\u304c\u4e00\u822c\u7684\u3067\u3059\u3002\u305d\u306e\u305f\u3081\u3001\u3068\u308a\u3042\u3048\u305a\u30a8\u30d3\u30c7\u30f3\u30b9\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u306b\u63d0\u793a\u3059\u308b\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u30ea\u30b9\u30af\u3068\u3057\u3066\uff08\u305f\u3068\u3048\u30702\u5024\u30a2\u30a6\u30c8\u30ab\u30e0\u306e\u5834\u5408\uff09\u3001\u5168\u4f53\u306e\u30a4\u30d9\u30f3\u30c8\u7387\u307e\u305f\u306f\u63a1\u7528\u7814\u7a76\u306e\u4e2d\u592e\u5024\u3092\u4e2d\u30ea\u30b9\u30af\u306e\u63a8\u5b9a\u5024\u3001\u4e0a\u304b\u30892\u756a\u76ee\u3042\u308b\u3044\u306f\u4e0b\u304b\u30892\u756a\u76ee\u306e\u5024\u3092\u305d\u308c\u305e\u308c\u9ad8\u30ea\u30b9\u30af\u3068\u4f4e\u30ea\u30b9\u30af\u306e\u63a8\u5b9a\u5024\u3068\u3057\u3066\u5229\u7528\u3057\u3001\u300c\u76f8\u5bfe\u52b9\u679c\u300d\u3092\u7d76\u5bfe\u52b9\u679c\u3068\u3068\u3082\u306b\u63d0\u793a\u3059\u308b\u3053\u3068\u304cGRADE\u304c\u52e7\u3081\u3066\u3044\u308b\u624b\u6cd5\u3067\u3059\u3002<\/p>\n<p>\u3057\u304b\u3057\u3001\u63a8\u5968\u4f5c\u6210\u3092\u76ee\u7684\u3068\u3059\u308bCPG\u306e\u5834\u5408\u306f\u3001\u898b\u8fbc\u307e\u308c\u308b\u4ecb\u5165\u6cbb\u7642\u306e\u5229\u76ca\u304c\u3001\u5bb3\u3084\u30b3\u30b9\u30c8\u306b\u898b\u5408\u3046\u304b\u3069\u3046\u304b\u306e\u6bd4\u8f03\u3092\u3001\uff08\u76f8\u5bfe\u52b9\u679c\u3067\u306f\u306a\u304f\uff09\u300c\u7d76\u5bfe\u52b9\u679c\u300d\u3092\u4f7f\u3063\u3066\u8a55\u4fa1\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n<p>\u4f8b\u3048\u3070\u3001<br \/>\n\uff08A)\u5fc3\u623f\u7d30\u52d5\u60a3\u8005\u306b\u304a\u3051\u308b\u8133\u5352\u4e2d\u30ea\u30b9\u30af\u6e1b\u5c11\u306e\u30ef\u30eb\u30d5\u30a1\u30ea\u30f3\u52b9\u679c\u306f\u76f8\u5bfe\u30ea\u30b9\u30af\uff08RR\uff09\u3068\u3057\u3066\u7d0435%\uff08ARR=0.65\uff09\u3067\u3059\u3002\u305d\u3053\u3067\u3001\u8133\u5352\u4e2d\u306e\u5e74\u9593\u767a\u75c7\u304c2%\uff0820\/1000\uff09\u306e\u60a3\u8005\u306e\u30ef\u30eb\u30d5\u30a1\u30ea\u30f3\u6cbb\u7642\u3067\u306f\u8133\u5352\u4e2d\u306e\u7d76\u5bfe\u30ea\u30b9\u30af\u6e1b\u5c11\u306f20 x 0.65 \/1000 = 15\/1000\u3067\u3059\u3002<\/p>\n<p>\n\uff08B)\u4e00\u65b9\u3001CHADS2\u30b9\u30b3\u30a2\uff1d\uff12\u3067\u3001\u8133\u5352\u4e2d\u306e\u5e74\u9593\u767a\u75c7\u30ea\u30b9\u30af\u304c4.5%\uff0845\/1000\uff09\u306e\u60a3\u8005\u306e\u30ef\u30eb\u30d5\u30a1\u30ea\u30f3\u6cbb\u7642\u3067\u306f\u3001\u8133\u5352\u4e2d\u306e\u7d76\u5bfe\u30ea\u30b9\u30af\u6e1b\u5c11\u306f45 x 0.65 \/1000 = 30\/1000\u3067\u3059\u3002<\/p>\n<p>\u3053\u306e\u3088\u3046\u306b\u3001\u540c\u3058\u201d\u76f8\u5bfe\u52b9\u679c\u201d\u3067\u3082\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u30ea\u30b9\u30af\u306b\u3088\u3063\u3066\u3001\u5f53\u8a72\u4ecb\u5165\u306e\u201d\u7d76\u5bfe\u52b9\u679c\u201d\u304c\u7570\u306a\u308b\u3053\u3068\u304b\u3089\u3001\u63a8\u5968\u4f5c\u6210\u306b\u304a\u3044\u3066\u306f\u3001\u30a2\u30a6\u30c8\u30ab\u30e0\u306e\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u30ea\u30b9\u30af\u3092\u5fc5\u8981\u3067\u3042\u308c\u3070\u8907\u6570\u60f3\u5b9a\u3057\u3066\u4ed6\u306e\u30a2\u30a6\u30c8\u30ab\u30e0\u3068\u6bd4\u8f03\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n<p>\u306a\u304a\u3001\u3053\u306e\u70b9\u306b\u3064\u3044\u3066\u306f\u3001<a href=\"http:\/\/www.grade-jpn.com\/grade2e-cover.html\">GRADE2\u7248\u306e4.5-3.3.3\uff5e3.2.3\u7ae0<\/a>\u306b\u3082\u8a73\u8ff0\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n<\/td>\n<\/tr>\n<\/table>\n<p>\n&nbsp;<br \/>\n<\/p>\n<table summary=\"baselinerisk2\" border=\"1\" style=\"border-collapse:collapse;border:none;\">\n<tr>\n<td style=\"border:1px solid #000000; padding:5px; background:#FFEFD5;\">\n<p><b>\u25cf\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u30ea\u30b9\u30af\u306e\u60f3\u5b9a\u306f\u3069\u306e\u3088\u3046\u306b\u3059\u308b\u306e\u304b\uff1f<\/b><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td style=\"border:1px solid #000000; padding:5px;background:#ffffff;\">\n<p>\n\u6cbb\u7642\u3084\u8a3a\u65ad\u30fb\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u3068\u540c\u69d8\u306b\u3001\u9069\u683c\u57fa\u6e96\u3092\u8a2d\u5b9a\u3057\u3066\u3001\u53ef\u80fd\u306a\u3089\u3070\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u306b\u3088\u308a\u7d71\u5408\u3057\u307e\u3059\uff08body of evidence\uff09\u3002<br \/>\n\u7d71\u5408\u30c4\u30fc\u30eb\u306b\u306f\u3001R\u3084STATA\u306a\u3069\u3092\u5229\u7528\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n<p>\u4f8b\u3001<b>Metaprop<\/b>&#8216;s DerSimonian and Laird random effects model, with a binomial distribution to model within study variability or stabilise variances by applying <strong>Freeman-Tukey double arcsine transformation<\/strong>.<br \/>\n\u30fb\u30fb\u30fb\u7d71\u8a08\u5b66\u8005\u306e\u65b9\u3005\u306b\u306f\u304a\u306a\u3058\u307f\u306a\u306e\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u304c\u30fb\u30fb\u30fb<\/p>\n<\/td>\n<\/tr>\n<\/table>\n<p>\n&nbsp;<br \/>\n<\/p>\n<table summary=\"baselinerisk3\" border=\"1\" style=\"border-collapse:collapse;border:none;\">\n<tr>\n<td style=\"border:1px solid #000000; padding:5px;background:#FFEFD5;\">\n<p><b>\u25cf\u4e88\u5f8c\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u306eGRADE\u8a55\u4fa1\u306f\u3069\u306e\u3088\u3046\u306b\u5b9f\u65bd\u3059\u308b\u306e\u304b\uff1f<\/b><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td style=\"border:1px solid #000000; padding:5px;background:#ffffff;\">\n<p>\u4e88\u5f8c\u306b\u95a2\u3059\u308b\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u78ba\u5b9f\u6027\uff08\u8cea\uff09\u306e\u8a55\u4fa1\u306b\u306f\u3001\u4e0b\u56f3\u306eAF\uff08analytic framework\uff09\u306b\u793a\u3059\u6bb5\u968e\u306b\u304a\u3044\u3066\u3001\u300c\u4e88\u5f8cGRADE\u300d\u3092\u6d3b\u7528\u3057\u307e\u3059\u3002\uff08<a href=\"http:\/\/www.grade-jpn.com\/grade_materials.html\">http:\/\/www.grade-jpn.com\/grade_materials.html<\/a>\u306b\u3042\u308b\u201c\u4e88\u5f8c\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u306eGRADE\u8a55\u4fa1\u3092\u53c2\u7167\uff09<\/p>\n<p>\n<a href=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2016\/12\/af_prognosis_grade.jpg\"><img decoding=\"async\" src=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2016\/12\/af_prognosis_grade.jpg\" alt=\"af_prognosis_grade\" style=\"border:2px dotted #ff8080;\" width=\"75%\" class=\"aligncenter size-full wp-image-6359\" srcset=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2016\/12\/af_prognosis_grade.jpg 1138w, http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2016\/12\/af_prognosis_grade-300x162.jpg 300w, http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2016\/12\/af_prognosis_grade-768x415.jpg 768w, http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2016\/12\/af_prognosis_grade-1024x553.jpg 1024w\" sizes=\"(max-width: 1138px) 100vw, 1138px\" \/><\/a><br \/>\n<\/p>\n<p>\u4e88\u5f8c\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u306b\u95a2\u3059\u308bGRADE\u8a55\u4fa1\u306f\u3001\u300c\u6cbb\u7642GRADE\u300d\u3068\u540c\u69d8\u306b\u3001\uff18\u3064\u306e\u30c9\u30e1\u30a4\u30f3\u3092\u5229\u7528\u3057\u307e\u3059\u304c\u3001\u4e00\u90e8\u306e\u30c9\u30e1\u30a4\u30f3\u306f\u300c\u6cbb\u7642GRADE\u300d\u3068\u306f\u7570\u306a\u308b\u30c4\u30fc\u30eb\u3084\u7570\u306a\u308b\u57fa\u6e96\u3092\u4f7f\u3063\u3066\u8a55\u4fa1\u3092\u5b9f\u65bd\u3059\u308b\u3053\u3068\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n<p>\u4f8b\u3048\u3070\u3001Risk of bias\u306f\u3001Quality in Prognosis Study\uff08QUIPS\uff09\u3001\u6539\u8a02\u7248Newcastle Ottawa\uff08NO\uff09\u30c4\u30fc\u30eb<a href=\"http:\/\/www.grade-jpn.com\/jama_evidence.html\">\u3001\u300e\u533b\u5b66\u6587\u732e\u306e\u305f\u3081\u306e\u30e6\u30fc\u30b6\u30fc\u30ba\u30ac\u30a4\u30c9\uff08Users Guides to the Medical Literature\uff09\u300f\uff082\u7248\u306e18\u7ae0\uff09<\/a>\u306a\u3069\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n<p>\u5165\u624b\u3057\u305f\u4e88\u5f8c\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u304c\u3001\u8a2d\u5b9a\u3057\u305f\u81e8\u5e8a\u7591\u554f\uff08CQ\uff09\u306e\u4ee3\u8868\u7684\u60a3\u8005\u30b5\u30f3\u30d7\u30eb\u3067\u306a\u3044\u306a\u3089\u3070RoB\u306b\u3088\u308b\u7b49\u7d1a\u30c0\u30a6\u30f3\u3001\u4ee3\u8868\u7684\u60a3\u8005\u30b5\u30f3\u30d7\u30eb\u3067\u3042\u3063\u3066\u3082CPG\u306b\u304a\u3051\u308b\u30bb\u30c3\u30c6\u30a3\u30f3\u30b0\u3068\u4e00\u81f4\u3057\u306a\u3044\u306a\u3089\u3070\u3001&#8221;indirectness&#8221;\u306e\u305f\u3081\u306e\u7b49\u7d1a\u30c0\u30a6\u30f3\u3001\u307e\u305f\u306f&#8221;\u30b5\u30d6\u30b0\u30eb\u30fc\u30d7\u89e3\u6790&#8221;\u306e\u5fc5\u8981\u6027\u304c\u3067\u3066\u304f\u308b\u3053\u3068\u306b\u306a\u308a\u307e\u3059\u3002\u305d\u3057\u3066\u3001\u30b5\u30d6\u30b0\u30eb\u30fc\u30d7\u89e3\u6790\u306e\u53ef\u80fd\u6027\u304c\u3042\u308b\u304b\u3082\u3057\u308c\u306a\u3044\u3068\u3044\u3046\u3053\u3068\u306f\u3001\u201d\u4e8b\u524d\u201d\u306b\u6c7a\u3081\u3066\u304a\u304f\u3079\u304d\uff17\u3064\u306e\u9805\u76ee\uff08JAMA-UG 3e\u3067\u306f5\u9805\u76ee\uff09\u3092\u610f\u8b58\u3059\u308b\u5fc5\u8981\u304c\u3042\u308b\u3053\u3068\u3092\u610f\u5473\u3057\u3066\u3044\u307e\u3059\uff08\u5177\u4f53\u7684\u306b\u306f\u3001<a href=\"http:\/\/www.grade-jpn.com\/jama_evidence.html\">\u300e\u533b\u5b66\u6587\u732e\u306e\u305f\u3081\u306e\u30e6\u30fc\u30b6\u30fc\u30ba\u30ac\u30a4\u30c9\u7b2c2\u7248\u300f<\/a>\u306e\u201d\u30b5\u30d6\u30b0\u30eb\u30fc\u30d7\u89e3\u6790\u306echapter\u3092\u53c2\u7167\uff09\u3002<\/p>\n<p>\u6ce8\uff1a\u4ed6\u306e\u30c9\u30e1\u30a4\u30f3\u306b\u95a2\u3059\u308b\u9055\u3044\u306b\u3064\u3044\u3066\u306f\u3001GRADE working group\u306b\u3088\u308b\u95a2\u9023\u8ad6\u6587\u3092\u53c2\u7167\u304f\u3060\u3055\u3044\u3002<\/p>\n<\/td>\n<\/tr>\n<\/table>\n<p>\n&nbsp;<br \/>\n<\/p>\n<table summary=\"baselinerisk3\" border=\"1\" style=\"border-collapse:collapse;border:none;\">\n<tr>\n<td style=\"border:1px solid #000000; padding:5px;background:#FFEFD5;\">\n<p><b>\u25cf\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u30ea\u30b9\u30af\u306b\u95a2\u3059\u308b\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u306e\u5177\u4f53\u4f8b\uff1aTriple-X\u4f8b<\/b><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td style=\"border:1px solid #000000; padding:5px;background:#ffffff;\">\n<p>\u300c<strong><a href=\"http:\/\/aihara.la.coocan.jp\/?p=5030\">\u89e3\u8aac\u30b7\u30ea\u30fc\u30ba\u306e3.11<\/a><\/strong>\u300d\u306e\u4eee\u60f3\u30c7\u30fc\u30bf\uff08Triple-X\uff09\u3092\u4f7f\u3063\u3066\u3001\u5fc3\u7b4b\u6897\u585e\u306e\u30a2\u30a6\u30c8\u30ab\u30e0\u306b\u95a2\u3059\u308bRCT\uff086\u4ef6\uff09\u306e\u5bfe\u7167\u7fa4\uff08\u89b3\u5bdf\u7814\u7a76\uff09\u3092\u7d71\u5408\u3057\u305f\u3082\u306e\u304c\u4ee5\u4e0b\u3067\u3059\u3002<\/p>\n<p><a href=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2016\/12\/prognosis_forest_tripleX.jpg\"><img decoding=\"async\" src=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2016\/12\/prognosis_forest_tripleX.jpg\" alt=\"prognosis_forest_triplex\" width=\"90%\" class=\"aligncenter size-full wp-image-6401\" srcset=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2016\/12\/prognosis_forest_tripleX.jpg 981w, http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2016\/12\/prognosis_forest_tripleX-300x231.jpg 300w, http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2016\/12\/prognosis_forest_tripleX-768x590.jpg 768w\" sizes=\"(max-width: 981px) 100vw, 981px\" \/><\/a><br \/>\n<\/p>\n<p>\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u30ea\u30b9\u30af\u306e\u7d71\u5408\u63a8\u5b9a\u5024\u306f\u3001\u30d5\u30a9\u30ec\u30b9\u30c8\u30d7\u30ed\u30c3\u30c8\u3067\u308f\u304b\u308b\u3088\u3046\u306b0.28 (0.24-0.32: RE)\u30010.28 (0.26-0.30\uff1aFE)\u3067\u3059\u3002\u305d\u3057\u3066\u3001\u5b9f\u969b\u306e\u30c7\u30fc\u30bf\u306e\u7bc4\u56f2\u306f\u30010.20\uff5e0.32\u3067\u3059\uff08\u4e0a\u8a18\u30ea\u30f3\u30af\u300c\u89e3\u8aac3.11\u300d\u53c2\u7167\uff09\u3002<\/p>\n<p><\/p>\n<p>\u3055\u3089\u306b\u3001\u3053\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u7dcf\u4f53\u306e\u78ba\u5b9f\u6027\u306b\u95a2\u3057\u3066GRADE\u8a55\u4fa1\u3057\u305f\u30a8\u30d3\u30c7\u30f3\u30b9\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u304c\u4ee5\u4e0b\u3067\u3059\u3002<br \/>\n\u3064\u307e\u308a\u3001\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u30ea\u30b9\u30af\u306b\u95a2\u3059\u308b\u30a8\u30d3\u30c7\u30f3\u30b9\u306f<strong>\u300cHigh\uff08\u9ad8\uff09\u300d\u306e\u78ba\u5b9f\u6027<\/strong>\u3068\u3044\u3046\u3053\u3068\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n<p><b>\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u78ba\u5b9f\u6027\uff08GRADE\u306e\u5b9a\u7fa9\uff09\uff1a<br \/>\n\u300c\u9ad8\u300d\uff1d\u771f\u306e\u30ea\u30b9\u30af\u304c\u767a\u751f\u7387\u306e\u63a8\u5b9a\u5024\u306b\u8fd1\u4f3c\u3059\u308b\u3068\u3044\u3046\u78ba\u5b9f\u6027\u304c\u9ad8\u3044<\/b><\/p>\n<p>\n<a href=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2016\/12\/evidence_profile_prognosis_XXX.jpg\"><img decoding=\"async\" src=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2016\/12\/evidence_profile_prognosis_XXX.jpg\" alt=\"evidence_profile_prognosis_xxx\" width=\"100%\" class=\"aligncenter size-full wp-image-6414\" \/><\/a><br \/>\n\n<\/td>\n<\/tr>\n<\/table>\n<p><\/p>\n<p>\u3053\u306e\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u30ea\u30b9\u30af\u306b\u95a2\u3059\u308b\u691c\u8a0e\u304c\u3069\u308c\u307b\u3069\u91cd\u8981\u306a\u3082\u306e\u304b\u3092\u3001\u6b21\u56de\u306f\u5b9f\u969b\u306eGRADE\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3092\u4f7f\u3063\u3066\u89e3\u8aac\u3057\u307e\u3059\uff08\u304a\u305d\u3089\u304f\u3001\u3053\u308c\u304c\u56fd\u5185\u3067\u76ee\u306b\u3059\u308b\u521d\u3081\u3066\u306e\u300c<strong>\u4e88\u5f8c\u306eGRADE\u30a8\u30d3\u30c7\u30f3\u30b9\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb<\/strong>\u300d\u306b\u306a\u308b\u3053\u3068\u3067\u3057\u3087\u3046\uff09\u3002<br \/>\n\u524d\u8ff0\u306e\u3088\u3046\u306b\u3001\u6c7a\u3057\u3066\u3001\u201d\u30a8\u30d3\u30c7\u30f3\u30b9\u30c6\u30fc\u30d6\u30eb\u304c\u3067\u304d\u305f\u306e\u3067\u30fb\u30fb\u30fb\u63a8\u5968\u4f5c\u6210\u201d\u3078\u3068\u6025\u3044\u3067\u306f\u3044\u3051\u307e\u305b\u3093\u3002<\/p>\n<p>\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u30ea\u30b9\u30af\u3068\u540c\u3058\u304f\u4e8b\u524d\u306b\u691c\u8a0e\u3059\u3079\u304d\u3001\u3068\u3066\u3082\u91cd\u8981\u306a\u8981\u56e0\u304c\u3042\u308b\u304b\u3089\u3067\u3059\u3002<\/p>\n<p>&nbsp;<br \/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>[GRADE-CPG\u89e3\u8aac\u8cc7\u6599-33] \u3000 GRADE\u306b\u5f93\u3063\u305f\u8a3a\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u4f5c\u6210\u306b\u304a\u3044\u3066\u306f\u3001SR\u30c1\u30fc\u30e0\u3068CPG\u30d1\u30cd\u30eb\u306e\u5354\u8abf\u304c\u5fc5\u8981\u3067\u3059\u304c\u3001\u4e21\u8005\u306b\u306f\u30a2\u30a6\u30c8\u30ab\u30e0\u306b\u5bfe\u3059\u308b\u8003\u3048\u65b9\u306e\u76f8\u9055\u304c\u3042\u308a\u307e\u3059\u3002\u305d\u3057\u3066\u3001\u63a8\u5968\u4f5c\u6210\u3092\u76ee\u7684\u3068\u3057\u305fCPG [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[455,5,436],"tags":[],"_links":{"self":[{"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/posts\/6336"}],"collection":[{"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=6336"}],"version-history":[{"count":82,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/posts\/6336\/revisions"}],"predecessor-version":[{"id":6463,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/posts\/6336\/revisions\/6463"}],"wp:attachment":[{"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=6336"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=6336"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=6336"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}