{"id":724,"date":"2014-04-30T11:14:58","date_gmt":"2014-04-30T02:14:58","guid":{"rendered":"http:\/\/aihara.la.coocan.jp\/?p=724"},"modified":"2014-05-02T16:30:50","modified_gmt":"2014-05-02T07:30:50","slug":"minds%e8%a8%ba%e7%99%82%e3%82%ac%e3%82%a4%e3%83%89%e3%83%a9%e3%82%a4%e3%83%b3%e4%bd%9c%e6%88%90%e3%83%9e%e3%83%8b%e3%83%a5%e3%82%a2%e3%83%ab%ef%bc%882014%ef%bc%89%e3%81%ae%e5%95%8f%e9%a1%8c","status":"publish","type":"post","link":"http:\/\/aihara.la.coocan.jp\/?p=724","title":{"rendered":"Minds\u8a3a\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u4f5c\u6210\u30de\u30cb\u30e5\u30a2\u30eb\uff082014\uff09\u306e\u554f\u984c"},"content":{"rendered":"<p>Minds\u8a3a\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u4f5c\u6210\u30de\u30cb\u30e5\u30a2\u30eb\u3000ver.1.0 (2014.03.31)\u3067\u8a18\u8f09\u3055\u308c\u3066\u3044\u308b\u8a3a\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u4f5c\u6210\u306e\u305f\u3081\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u5f37\u3055\u3084\u63a8\u5968\u306e\u5f37\u3055\u306e\u8a55\u4fa1\u4f8b\u3092\u307f\u3066\u307f\u3088\u3046\u3002<\/p>\n<p><strong>\u25a0\u30af\u30ea\u30cb\u30ab\u30eb\u30af\u30a8\u30b9\u30c1\u30e7\u30f3<\/strong><\/p>\n<ul>\n<li>\u5bfe\u8c61\uff1a\u865a\u8840\u6027\u8133\u5352\u4e2d\uff0879\u6b73\u307e\u3067\uff09<\/li>\n<li>\u4ecb\u5165\uff1a6\u6642\u9593\u4ee5\u5185\u306e\u30a2\u30eb\u30c6\u30d7\u30e9\u30fc\u30bc iv<\/li>\n<li>\u5bfe\u7167\uff1a\u30d7\u30e9\u30bb\u30dc<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p><strong>\u25a0\u30a2\u30a6\u30c8\u30ab\u30e0\u3068\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u5f37\u3055<\/strong><br \/>\n<a href=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2014\/04\/4-7.jpg\"><img decoding=\"async\" loading=\"lazy\" class=\"wp-image-725 alignleft\" src=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2014\/04\/4-7-300x86.jpg\" alt=\"4-7\" width=\"604\" height=\"173\" \/><\/a><\/p>\n<div class=\"clearer\"><\/div>\n<ul>\n<li>(1) 6\u304b\u6708\u5f8c\u306e\u7dcf\u6b7b\u4ea1\uff1a\uff08\u91cd\u8981\u6027\uff19\uff09 RCT3\u4ef6\u304b\u3089\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u3067\u3001\u975e\u76f4\u63a5\u6027(-1)\u3001464\/1976\uff08alteplase)\u00a0\u00a0 vs 456\/1960\uff08control)\u3001\u76f8\u5bfe\u30ea\u30b9\u30af1.01 (95%CI 0.91-1.14) \u306b\u3082\u304b\u304b\u308f\u3089\u305a\u3001\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u5f37\u3055\u306fA\uff08\u5f37\uff09\u3002<\/li>\n<li>(2) 6\u304b\u6708\u5f8c\u306e\u4f9d\u5b58\u6027(ADL)\uff1a\uff08\u91cd\u8981\u6027\uff17\uff09 RCT3\u4ef6\u304b\u3089\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u3067\u3001\u975e\u76f4\u63a5\u6027(-1)\u30011176\/1976\uff08alteplase)\u00a0\u00a0\u00a0vs 1226\/1960\uff08control)\u3001\u76f8\u5bfe\u30ea\u30b9\u30af0.92 (95%CI 0.83-1.04) \u306b\u3082\u304b\u304b\u308f\u3089\u305a\u3001\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u5f37\u3055\u306fB\uff08\u4e2d\uff09\u3002<\/li>\n<li>(3) 1\u9031\u9593\u4ee5\u5185\u306e\u8133\u51fa\u8840\uff1a\uff08\u91cd\u8981\u6027\uff19\uff09 RCT3\u4ef6\u304b\u3089\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u3067\u3001\u975e\u76f4\u63a5\u6027(-1)\u3001144\/1975\uff08alteplase)\u00a0 vs 29\/1960\uff08control)\u3001\u76f8\u5bfe\u30ea\u30b9\u30af4.43 (95%CI 2.07-9.48) \u306b\u3082\u304b\u304b\u308f\u3089\u305a\u3001\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u5f37\u3055\u306fA\uff08\u5f37\uff09\u3002<\/li>\n<\/ul>\n<p>========================<br \/>\n\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u7b49\u7d1a\u30c0\u30a6\u30f3\u306f\u3069\u3046\u306a\u3063\u3066\u3044\u308b\u306e\u304b\u3001\u8a55\u4fa1\u306e\u5224\u5b9a\u7406\u7531\u304c\u308f\u304b\u308a\u307e\u305b\u3093\u3002<\/p>\n<p>&nbsp;<\/p>\n<p><strong>\u25a0\u63a8\u5968\u306e\u5f37\u3055<\/strong><\/p>\n<table style=\"border-collapse: collapse; border: none;\" border=\"1\" summary=\"minds\">\n<tbody>\n<tr>\n<td style=\"border: 1px solid #000000;\" width=\"725\">80\u6b73\u672a\u6e80\u306e\u767a\u75c7\u5f8c3\u6642\u9593\u3092\u8d85\u3048\u305f\u6025\u6027\u8133\u6897\u585e\u60a3\u8005\u306b\u5bfe\u3057\u3066\u3001\u7dcf\u6b7b\u4ea1\u7387\u4f4e\u4e0b\u3001ADL\u4fdd\u6301\u3001\u8133\u51fa\u8840\u9632\u6b62\u3092\u8003\u616e\u3057\u305f\u5834\u5408\u30016\u6642\u9593\u4ee5\u5185\u306ert-PA\u6295\u4e0e\u3092\u63d0\u6848\u3059\u308b\u3002\uff08\u5f31\u3044\u63a8\u5968\uff09<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<ul>\n<li>\u201d\u4fa1\u5024\u89b3\u3084\u597d\u307f\uff1a\u672c\u63a8\u5968\u306e\u4f5c\u6210\u306b\u3042\u305f\u3063\u3066\u306f\u3001\u6025\u6027\u8133\u6897\u585e\u60a3\u8005\u306b\u5bfe\u3059\u308b\u6b7b\u4ea1\u7387\u4f4e\u4e0b\u306e\u4f4e\u4e0b\u3001ADL\u4fdd\u6301\u3001\u8133\u51fa\u8840\u62cd\u5b50\u3092\u91cd\u8981\u8996\u3057\u305f\u201d<\/li>\n<li>\u201d\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u7dcf\u62ec\uff08\u91cd\u5927\u306a\u30a2\u30a6\u30c8\u30ab\u30e0\u5168\u822c\u306b\u5168\u4f53\u7684\u306a\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u5f37\u3055\uff09 \u30fb\u30fb\u30fbB\uff08\u4e2d\uff09\u201d<\/li>\n<li>\u201d\u76ca\u3068\u5bb3\u306e\u30d0\u30e9\u30f3\u30b9\u306f\u4e0d\u78ba\u5b9f\u3002\u8133\u51fa\u8840\u306f\u5897\u52a0\u3059\u308b\u304c\u3001\u6b7b\u4ea1\u7387\u306f\u307b\u3068\u3093\u3069\u5dee\u304c\u306a\u304f\u3001ADL\u4fdd\u6301\u3082\u308f\u305a\u304b\u306b\u6539\u5584\u3059\u308b\u3002\u3053\u308c\u306f\u3001\u30a2\u30eb\u30c6\u30d7\u30e9\u30fc\u30bc\u6295\u4e0e\u306b\u3088\u3063\u3066\u6539\u5584\u3059\u308b\u60a3\u8005\u3082\u3044\u308b\u3053\u3068\u3092\u793a\u3057\u3066\u3044\u308b\u3002\u201d<\/li>\n<\/ul>\n<p>======================<\/p>\n<p>\u4e0a\u8a18\u306e\u8a55\u4fa1\u5224\u5b9a\u306f\u5168\u304f\u7406\u89e3\u3067\u304d\u307e\u305b\u3093\u3002<\/p>\n<p>\u60a3\u8005\u306b\u3068\u3063\u3066\u6700\u3082\u91cd\u5927\u306a\u30a2\u30a6\u30c8\u30ab\u30e0\u306b\u95a2\u3059\u308b\u5168\u4f53\u7684\u306a\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u8cea\u306f\u3001\uff08\u8457\u8005\u3089\u306e\u5224\u5b9a\u306b\u5f93\u3048\u3070\uff09\u3001\u201d<strong>A\u201d<\/strong>\u3067\u3059\u3002<\/p>\n<p>\u5229\u76ca\u3068\u5bb3\u306e\u30d0\u30e9\u30f3\u30b9\u306f\u3001\u660e\u3089\u304b\u306b\u5bb3\u304c\u5927\u304d\u304f\u3001\u5bb3\u306e\u5185\u5bb9\u306f\u3001\u201d1\u9031\u9593\u4ee5\u5185\u306e\u8133\u51fa\u8840\u3067\u3042\u308a\u305d\u306e\u307b\u3068\u3093\u3069\u304c\u6b7b\u4ea1\u3059\u308b\u201d\u3068\u3044\u3046\u3082\u306e\u3067\u3059\u3002NNH(Number needed to harm)\u306b\u3057\u3066\u3001<strong>17 (95%CI 14-21) <\/strong>\u3068\u5927\u304d\u3044\u3002\u3057\u304b\u3057\u3001\u672c\u66f8\u306e\u89e3\u8aac\u4f8b\u306b\u304a\u3044\u3066\u306f\u3001\u3053\u306e\u6025\u6027\u671f\u306e\u5bb3\u3068\u6bd4\u8f03\u3057\u3066\u3082\u30016\u304b\u6708\u5f8c\u306eADL\u4fdd\u6301\uff08\u3057\u304b\u3082\u305d\u306e\u5dee\u306f\u7d71\u8a08\u5b66\u7684\u306b\u306f\u6709\u610f\u3067\u306f\u306a\u3044\uff09\u3068\u3044\u3046\u30a8\u30d3\u30c7\u30f3\u30b9\u3092\u63a1\u7528\u3057\u3001\u30ec\u30d9\u30eb\u201dB\u201d\u3068\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u300c\u6025\u6027\u671f\u8133\u5352\u4e2d\u306e\u6cbb\u7642\u4ecb\u5165\u306e\u30a2\u30a6\u30c8\u30ab\u30e0\u3092\u554f\u984c\u3068\u3057\u3066\u3044\u308b\u72b6\u6cc1\u3067\u3001\u534a\u5e74\u5f8c\u306eADL\u3068\u3044\u3046\u30a2\u30a6\u30c8\u30ab\u30e0\u304c\u91cd\u5927\u306a\u3082\u306e\u306a\u306e\u3060\u308d\u3046\u304b\u300d<\/p>\n<p>\u300c\u8133\u51fa\u8840\u30ea\u30b9\u30af\u304c4\u500d\uff08\u6700\u60aa\u306a\u308910\u500d\uff09\u3082\u591a\u304f\u305d\u306e\u6b86\u3069\u304c\u6b7b\u4ea1\u3059\u308b\u3068\u3044\u3046\u521d\u671f\u306e\uff11\u9031\u9593\u3092\u3057\u306e\u3050\u3068\u30016\u304b\u6708\u5f8c\u306eADL\u4fdd\u6301\u304c\u5f97\u3089\u308c\u308b\u201c\u304b\u3082\u201d\u3057\u308c\u306a\u3044\u300d\u3068\u3044\u3046\u30a2\u30eb\u30c6\u30d7\u30e9\u30fc\u30bc\u6cbb\u7642\u3092\u81e8\u5e8a\u533b\u3068\u3057\u3066\u3001recommend for\u306e\u65b9\u5411\u6027\u3068\u3057\u3066\u63a8\u5968\u3059\u308b\u3060\u308d\u3046\u304b\uff1f<\/p>\n<p>&nbsp;<\/p>\n<p>\u63d0\u793a\u30c7\u30fc\u30bf\u304b\u3089\u3059\u308c\u3070\u3001\u201ddo no harm!\u201d\u306e\u539f\u5247\u304b\u3089\u3001\u660e\u3089\u304b\u306b\u3001<strong>Recommend against\/A\u3000<\/strong>\u3068\u5224\u5b9a\u3059\u3079\u304d\u3067\u3057\u3087\u3046\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>\u307e\u3042\u3001\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u4f5c\u6210\u306e\u624b\u9806\u3068\u3057\u3066\u306e\u8a18\u8f09\u4f8b\u306a\u306e\u3067\u3001\u3053\u308c\u3082\u3042\u308a\u304b\u3068\u3082\u8a00\u3048\u307e\u3059\u304c\u3001\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u8cea\u3084\u63a8\u5968\u306e\u5f37\u3055\u306eGRADE\u8a55\u4fa1\u306b\u95a2\u3059\u308b\u89e3\u8aac\u3068\u3057\u3066\u306f\u4e0d\u9069\u5207\u3068\u601d\u3044\u307e\u3059\u3002<\/p>\n<p>COI\u306e\u9805\u306f\u3088\u304f\u8a18\u8f09\u3055\u308c\u3066\u3044\u308b\u3068\u601d\u3044\u307e\u3059\u304c\u3001\u4e0a\u8a18\u8a18\u8f09\u4f8b\u3092\u307f\u308b\u304b\u304e\u308a\u306f\u3001\u30a2\u30eb\u30c6\u30d7\u30e9\u30fc\u30bc\u306e\u88fd\u85ac\u4f1a\u793e\u3068\u306a\u306b\u304b\u95a2\u9023\u304c\u3042\u308b\u30d1\u30cd\u30eb\u306e\u610f\u898b\u304c\u5f37\u304f\u53cd\u6620\u3057\u3066\u3044\u308b\u306e\u304b\u3068\u52d8\u9055\u3044\u3055\u308c\u308b\u53ef\u80fd\u6027\u3082\u3042\u308b\u3067\u3057\u3087\u3046\u3002<\/p>\n<p>\u8ab0\u304c\u898b\u3066\u3082\u672c\u30de\u30cb\u30e5\u30a2\u30eb\u306fGRADE\u30b7\u30b9\u30c6\u30e0\u3092\u53c2\u8003\u306b\u3057\u3066\u3044\u308b\u3053\u3068\u306f\u660e\u3089\u304b\u3067\u3059\u304c\u3001GRADE\u306b\u9806\u5b88\u3057\u3066\u3044\u308b\u3068\u3082\u660e\u8a18\u305b\u305a\u3001GRADE\u30b7\u30b9\u30c6\u30e0\u3092\u9069\u683c\u306b\u8a18\u8f09\u3057\u3066\u304a\u3089\u305a\u3001\u5229\u7528\u8005\u306e\u591a\u304f\u306f\u6df7\u4e71\u3059\u308b\u3053\u3068\u3060\u308d\u3046\u3002<\/p>\n<p>\u672c\u30de\u30cb\u30e5\u30a2\u30eb\u3092\u7684\u78ba\u306b\u5229\u7528\u3057\u3088\u3046\u3068\u3059\u308b\u3068\u3001\u305d\u308c\u306fGRADE\u3092\u6539\u5909\u3059\u308b\u3068\u3044\u3046\u65b9\u5411\u3068\u306a\u308a\u3001\u5927\u304d\u306a\u30b8\u30ec\u30f3\u30de\u3068\u306a\u308b\u3053\u3068\u3067\u3057\u3087\u3046\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>\u30fb\u30fb\u30fb\u30fb\u3069\u3046\u3059\u308bMinds\uff01<\/p>\n<p>&nbsp;<\/p>\n<p>\u9644\uff1a\u3061\u306a\u307f\u306b\u3001<strong>\u300crt -PA \uff08\u30a2\u30eb\u30c6\u30d7\u30e9\u30fc\u30bc\uff09\u9759\u6ce8\u7642\u6cd5 \u9069\u6b63\u6cbb\u7642\u6307\u91dd \u9069\u6b63\u6cbb\u7642\u6307\u91dd \u7b2c\u4e8c\u7248\uff082012\u5e74\uff09\u300d<\/strong>\u3067\u306f\u3001<br \/>\n<a href=\"http:\/\/www.jsts.gr.jp\/img\/rt-PA02.pdf\">http:\/\/www.jsts.gr.jp\/img\/rt-PA02.pdf<\/a><\/p>\n<p><strong>\u201d\u9759\u6ce8\u7528\u306e \u9759\u6ce8\u7528\u306e \u8840\u6813\u6eb6\u89e3\u85ac\u306b\u306f\u3001\u30a2\u30eb\u30c6\u30d7\u30e9\u30fc\u30bc\u3092\u7528\u3044\u308b [\u30a8\u30d3\u30c7\u30f3\u30b9 \u30ec\u30d9\u30eb \u30ec\u30d9\u30eb Ia, \u63a8\u5968 \u30b0\u30ec\u30fc\u30c9\u00a0 A\u201d<\/strong><\/p>\n<p>\u30fb\u30fb\u30fbMinds2007\u57fa\u6e96\u3092\u4f7f\u3046\u3068\u3001\uff08\u5229\u76ca\u3068\u5bb3\u306e\u30d0\u30e9\u30f3\u30b9\u306b\u3088\u308b\u63a8\u5968\u8a55\u4fa1\u3067\u306f\u306a\u3044\u305f\u3081\uff09\u3053\u306e\u3088\u3046\u306a\u8a55\u4fa1\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>GRADE\u3092\u9069\u5207\u306b\u5229\u7528\u3057\u305f\u3044\u65b9\u3005\u306f\u3001<strong>\u300c<a href=\"http:\/\/www.grade-jpn.com\/grade-cover.html\">\u8a3a\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u306e\u305f\u3081\u306eGRADE\u30b7\u30b9\u30c6\u30e0<\/a>\u300d<\/strong>\uff08\u76f8\u539f\u3001\u4ed6\u3001\u5f18\u524d\u3001\u51f8\u7248\u30e1\u30c7\u30a3\u30a2\u30012010\uff09\u3092\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Minds\u8a3a\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u4f5c\u6210\u30de\u30cb\u30e5\u30a2\u30eb\u3000ver.1.0 (2014.03.31)\u3067\u8a18\u8f09\u3055\u308c\u3066\u3044\u308b\u8a3a\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u4f5c\u6210\u306e\u305f\u3081\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u5f37\u3055\u3084\u63a8\u5968\u306e\u5f37\u3055\u306e\u8a55\u4fa1\u4f8b\u3092\u307f\u3066\u307f\u3088\u3046\u3002 \u25a0\u30af\u30ea\u30cb\u30ab\u30eb\u30af\u30a8\u30b9\u30c1\u30e7\u30f3 \u5bfe\u8c61\uff1a\u865a\u8840\u6027\u8133\u5352 [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[5,170],"tags":[432],"_links":{"self":[{"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/posts\/724"}],"collection":[{"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=724"}],"version-history":[{"count":71,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/posts\/724\/revisions"}],"predecessor-version":[{"id":800,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/posts\/724\/revisions\/800"}],"wp:attachment":[{"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=724"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=724"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=724"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}