{"id":7650,"date":"2017-02-28T10:12:40","date_gmt":"2017-02-28T01:12:40","guid":{"rendered":"http:\/\/aihara.la.coocan.jp\/?p=7650"},"modified":"2017-03-14T09:06:55","modified_gmt":"2017-03-14T00:06:55","slug":"nma%e3%82%a8%e3%83%93%e3%83%87%e3%83%b3%e3%82%b9%e3%81%ae%e5%bf%85%e8%a6%81%e6%80%a7%ef%bc%9a%ef%bc%88%e4%be%8b%ef%bc%89%e9%96%a2%e7%af%80%e3%83%aa%e3%82%a6%e3%83%9e%e3%83%81%e3%82%ac%e3%82%a4","status":"publish","type":"post","link":"http:\/\/aihara.la.coocan.jp\/?p=7650","title":{"rendered":"NMA\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u5fc5\u8981\u6027\uff1a\uff08\u4f8b\uff11\uff09\u95a2\u7bc0\u30ea\u30a6\u30de\u30c1\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3"},"content":{"rendered":"

\u5e74\u9593100\u4ef6\u306e\u30da\u30fc\u30b9\u3067\u51fa\u7248\u3055\u308c\u308b\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\uff08NMA\uff09<\/strong>\u306f\u3001\u3044\u307e\u3084\u3001\u8a3a\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u4f5c\u6210\u306b\u304a\u3044\u3066\u3001”exclude\u3067\u304d\u306a\u3044”\u30a8\u30d3\u30c7\u30f3\u30b9\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u305f\u3068\u3048\u3070\u3001\u56fd\u5185\u306e\u8a3a\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u306b\u304a\u3051\u308b\u6cbb\u7642\u4ecb\u5165\u306b\u95a2\u3059\u308b\u30a8\u30d3\u30c7\u30f3\u30b9\u3092\u8003\u3048\u308b\u3068\u3001\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u5f71\u97ff\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n

\u25cf\u95a2\u7bc0\u30ea\u30a6\u30de\u30c1\uff08RA\uff09\u8a3a\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f32014<\/a><\/b><\/p>\n\n\n\n\n\n
\n

RA-2014\u8a3a\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u306b\u304a\u3044\u3066\u306f\u3001\u56f3\u306b\u793a\u3059\u5404\u4ecb\u5165\u6cbb\u7642\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u304c\u3001\u201d\u6cbb\u7642\u306a\u3057<\/strong>\u201d\u3068\u6bd4\u8f03\u3055\u308c\u3066\u3044\u307e\u3057\u305f\u3002\u52b9\u679c\u6bd4\u8f03\u7814\u7a76\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u3068\u3057\u3066\u3001\u201d\u5f53\u8a72\u4ecb\u5165\u306a\u3057\u201d\u3068\u306e\u6bd4\u8f03\u3067\u3059\u3002\u30d6\u30ed\u30b0\uff1a2016\/12\/30<\/b><\/a><\/p>\n

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\u3055\u307e\u3056\u307e\u306a\u6cbb\u7642\u306e\u52b9\u679c\u306e\u9055\u3044\u3068\u3001\u305d\u306e\u78ba\u5b9f\u6027\uff08\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u8cea\uff09\u3092\u77e5\u308a\u305f\u3044\u306f\u305a\u3067\u3059\u3002\u305d\u3057\u3066\u3001\u63a8\u5968\u306e\u5f37\u3055\u3092\u6559\u3048\u3066\u307b\u3057\u3044\u3068\u9858\u3063\u3066\u3044\u308b\u306f\u305a\u3067\u3059\u3002
\n\uff08\u76f4\u63a5\u6bd4\u8f03\u30a8\u30d3\u30c7\u30f3\u30b9\u3068\u3001\u9593\u63a5\u6bd4\u8f03\u30a8\u30d3\u30c7\u30f3\u30b9\u3042\u308b\u3044\u306fNMA\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u78ba\u5b9f\u6027\u8a55\u4fa1\u306f\u3001GRADE2\u7248<\/a>\u3092\u53c2\u7167\u3057\u3066\u304f\u3060\u3055\u3044\uff09<\/p>\n<\/td>\n<\/tr>\n

\n

*\u95a2\u7bc0\u30ea\u30a6\u30de\u30c1\u8a3a\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f32014\u3067\u8a18\u8f09\u3055\u308c\u3066\u3044\u308bDMARDS<\/em><\/p>\n

\"\"<\/a><\/p>\n

\n

2016\u5e7412\u6708<\/strong>\u3001\u5f93\u6765\u306eNMA\u3067\u3088\u304f\u307f\u3089\u308c\u308b\u5229\u76ca\u3067\u306f\u306a\u304f\u3001\u91cd\u7be4\u306a\u6709\u5bb3\u4f5c\u7528\u306b\u95a2\u3059\u308b\u9593\u63a5\u6bd4\u8f03\u306e\u89e3\u6790\u3068\u3057\u3066\u3001\u4e0b\u8a18\u306eNMA\u8ad6\u6587\u304c\u767a\u8868\u3055\u308c\u307e\u3057\u305f\uff08\u3061\u306a\u307f\u306b\u3001GRADE\u3092\u4f7f\u3063\u305f\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u78ba\u5b9f\u6027\u8a55\u4fa1\uff09\u3002<\/p>\n

<\/p>\n

\n

Ref: Tarp S, et al. Risk of serious adverse effects of biological and targeted drugs in patients with rheumatoid arthritis: a systematic review meta-analysis. Rheumatology. 2016; doi:10.1093\/rheumatology\/kew442<\/a><\/p>\n<\/div>\n

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\n\n<\/td>\n<\/tr>\n

\n

\u3064\u307e\u308a\u3001NMA\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u63d0\u793a\u306e\u969b\u306b\u306f\u3001\u3055\u307e\u3056\u307e\u306a\u6cbb\u7642\u4ecb\u5165\u306b\u95a2\u3059\u308b\u3001\u308f\u305a\u304b\u306a\u5229\u76ca\u3084\u30e9\u30f3\u30ad\u30f3\u30b0\u306e\u9055\u3044\u306b\u6ce8\u76ee\u3059\u308b\u4ee5\u4e0a\u306b\u3001NMA\u306b\u3088\u308a\u6cbb\u7642\u4ecb\u5165\u306e\u91cd\u7be4\u306a\u6709\u5bb3\u4f5c\u7528\u306e\u5dee\u3092\u660e\u78ba\u306b\u3059\u308b\u5fc5\u8981\u304c\u3042\u308b\u3068\u3044\u3046\u4e3b\u5f35\u3067\u3059\u3002<\/p>\n

\u56fd\u5185\u306eRA\u8a3a\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u6539\u8a02\u306b\u304a\u3044\u3066\u3082\u3001\u6cbb\u7642\u306e\u5bb3\u306b\u95a2\u3059\u308b\u5dee\u306e\u6bd4\u8f03\u306b\u95a2\u3057\u3066\u3001NMA\u30a8\u30d3\u30c7\u30f3\u30b9\u3092\u7121\u8996\u3067\u304d\u306a\u3044\u3068\u3044\u3046\u3053\u3068\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n

\u3080\u3057\u308d\u3001\u201dDo no net harm\u201d<\/strong>\u3068\u3044\u3046EBM\u306e\u539f\u5247\u304b\u3089\u3082\u3001NMA\u3092\u6d3b\u7528\u3057\u305fharm\u306e\u63a8\u5b9a\u304c\u5fc5\u8981\u306a\u306e\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002<\/p>\n<\/td>\n<\/tr>\n<\/table>\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

\u5e74\u9593100\u4ef6\u306e\u30da\u30fc\u30b9\u3067\u51fa\u7248\u3055\u308c\u308b\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\uff08NMA\uff09\u306f\u3001\u3044\u307e\u3084\u3001\u8a3a\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u4f5c\u6210\u306b\u304a\u3044\u3066\u3001”exclude\u3067\u304d\u306a\u3044”\u30a8\u30d3\u30c7\u30f3\u30b9\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002 \u305f\u3068\u3048\u3070\u3001\u56fd\u5185\u306e\u8a3a\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3 […]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[458,16],"tags":[],"_links":{"self":[{"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/posts\/7650"}],"collection":[{"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=7650"}],"version-history":[{"count":37,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/posts\/7650\/revisions"}],"predecessor-version":[{"id":8458,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/posts\/7650\/revisions\/8458"}],"wp:attachment":[{"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=7650"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=7650"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=7650"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}