{"id":8434,"date":"2017-03-15T09:05:43","date_gmt":"2017-03-15T00:05:43","guid":{"rendered":"http:\/\/aihara.la.coocan.jp\/?p=8434"},"modified":"2017-03-15T09:05:43","modified_gmt":"2017-03-15T00:05:43","slug":"anca%e8%a8%ba%e7%99%82%e3%82%ac%e3%82%a4%e3%83%89%e3%83%a9%e3%82%a4%e3%83%b3%ef%bc%9a%e3%83%8d%e3%83%83%e3%83%88%e3%83%af%e3%83%bc%e3%82%af%e3%83%a1%e3%82%bf%e3%82%a2%e3%83%8a%e3%83%aa%e3%82%b7-2","status":"publish","type":"post","link":"http:\/\/aihara.la.coocan.jp\/?p=8434","title":{"rendered":"ANCA\u8a3a\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\uff1a\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9-(2)\u3000\u5bdb\u89e3\u7dad\u6301\u7642\u6cd5"},"content":{"rendered":"<p>ANCA\u8a3a\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f32017\u306b\u304a\u3051\u308b<b>\u5bdb\u89e3\u7dad\u6301\u7642\u6cd5<\/b>\u306e\u52b9\u679c\u3092\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\uff08NMA\uff09\u3092\u4f7f\u3063\u305f\u8996\u70b9\u3067\u8a55\u4fa1\u3057\u3066\u307f\u307e\u3059\u3002\u63a1\u7528\u3057\u305f\u30c7\u30fc\u30bf\u306f\u3059\u3079\u3066\u3001ANCA-2017\u3067\u8a18\u8f09\u3055\u308c\u3066\u3044\u308b\u3082\u306e\u3092\u5229\u7528\u3057\u307e\u3057\u305f\u3002<br \/>\n\u3053\u3053\u3067\u3082\u3001efficacy\u3068\u3001tolerability\u306e\uff12\u3064\u306e\u30a2\u30a6\u30c8\u30ab\u30e0\u3067\u6bd4\u8f03\u3057\u307e\u3057\u305f\u3002<\/p>\n<p>\u8a3a\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u306b\u304a\u3044\u3066\u8a18\u8f09\u3055\u308c\u3066\u3044\u308b\u3001Efficacy\uff08\u52b9\u80fd\uff09\u306b\u95a2\u3059\u308b\u6cbb\u7642\u306f\u3001POCY AZA RTX MTX MMF CsA\u306e6\u7a2e\u985e\u3067\u3057\u305f\u304c\u3001\u91cd\u7be4\u5408\u4f75\u75c7\u306b\u3064\u3044\u3066\u306f\u3001CsA\u306e\u8a18\u8f09\u304c\u306a\u304b\u3063\u305f\u306e\u3067\u3001CsA\u3092\u9664\u3044\u305f5\u7a2e\u985e\u306e\u7dad\u6301\u7642\u6cd5\u306b\u3064\u3044\u3066\u3001\u518d\u71c3\u3068\u91cd\u7be4\u5408\u4f75\u75c7\u3092\u6bd4\u8f03\u3057\u307e\u3057\u305f\u3002<\/p>\n<p>NMA\u306e\u65b9\u6cd5\u306f\u3001R(gemtc)\u306b\u3088\u308b<b>Bayesian NMA<\/b>\u3067\u3059\u3002<\/p>\n<p><b>\u25a0\u56f3\uff11. ANCA\u5bdb\u89e3\u7dad\u6301\u6cbb\u7642\u306b\u95a2\u3059\u308b\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u30d7\u30ed\u30c3\u30c8<\/b><\/p>\n<table width=\"100%\" summary=\"plot\" border=\"1\" style=\"border-collapse:collapse;border:none;\">\n<tr>\n<td style=\"border:1px solid #000000; padding:5px; background:#ffffff;\">\n<a href=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2017\/03\/nma_plot_3013.jpg\"><img decoding=\"async\" src=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2017\/03\/nma_plot_3013.jpg\" alt=\"\" width=\"60%\" class=\"aligncenter size-full wp-image-8442\" srcset=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2017\/03\/nma_plot_3013.jpg 678w, http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2017\/03\/nma_plot_3013-300x277.jpg 300w\" sizes=\"(max-width: 678px) 100vw, 678px\" \/><\/a>\n<\/td>\n<\/tr>\n<tr>\n<td style=\"border:1px solid #000000; padding:5px; background:#ffffff;\">\n<p>\uff15\u7a2e\u985e\u306e\u5c0e\u5165\u6cbb\u7642\uff08POCY, AZA, RTX, MTX, MMF\uff09\u306e\u6bd4\u8f03\u3067\u3059\u3002<\/p>\n<\/td>\n<\/tr>\n<\/table>\n<p>\n&nbsp;<br \/>\n&nbsp;<\/p>\n<p><b>\u25a0\u56f3\uff12\uff0e interval plot\uff08Efficacy\uff09<\/b><\/p>\n<table width=\"100%\" border=\"1\" style=\"border-collapse:collapse;border:none;\">\n<tr>\n<td style=\"border:1px solid #000000; padding:5px; background:#ffffff;\">\n<a href=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2017\/03\/ifplot_0313.jpg\"><img decoding=\"async\" src=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2017\/03\/ifplot_0313.jpg\" alt=\"\" width=\"80%\" class=\"aligncenter size-full wp-image-8443\" srcset=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2017\/03\/ifplot_0313.jpg 1127w, http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2017\/03\/ifplot_0313-300x148.jpg 300w, http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2017\/03\/ifplot_0313-768x379.jpg 768w, http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2017\/03\/ifplot_0313-1024x505.jpg 1024w\" sizes=\"(max-width: 1127px) 100vw, 1127px\" \/><\/a>\n<\/td>\n<\/tr>\n<tr>\n<td style=\"border:1px dotted #000000; padding:5px; background:#ffffff;\">\n<p>AZA\u3092\u5bfe\u7167\u3068\u3057\u3066\u6bd4\u8f03\u3057\u305f\u3001\u5bdb\u89e3\u7dad\u6301\u7642\u6cd5\u306e\u52b9\u679c\u306f\u3001\u660e\u3089\u304b\u306bRTX\u304c\u512a\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<\/td>\n<\/tr>\n<\/table>\n<p>\n&nbsp;<\/p>\n<p><b>\u25a0\u56f3\uff13\uff0e Efficacy\u306b\u95a2\u3059\u308b\u5404\u6cbb\u7642\u306e\u30e9\u30f3\u30ad\u30f3\u30b0\uff08Rankogram\uff09<\/b><\/p>\n<table width=\"100%\" summary=\"nma\" border=\"1\" style=\"border-collapse:collapse;border:none;\">\n<tr>\n<td style=\"border:1px solid #000000; padding:5px; background:#ffffff;\">\n<p><b>\u5404\u6cbb\u7642\u306e\u30e9\u30f3\u30ad\u30f3\u30b0<\/b><\/p>\n<p><a href=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2017\/03\/ranking_0313.jpg\"><img decoding=\"async\" src=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2017\/03\/ranking_0313.jpg\" alt=\"\" width=\"70%\" class=\"aligncenter size-full wp-image-8447\" srcset=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2017\/03\/ranking_0313.jpg 773w, http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2017\/03\/ranking_0313-300x279.jpg 300w, http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2017\/03\/ranking_0313-768x714.jpg 768w\" sizes=\"(max-width: 773px) 100vw, 773px\" \/><\/a>\n<\/td>\n<\/tr>\n<tr>\n<td style=\"border:1px dotted #000000; padding:5px; background:#ffffff;\">\n<p><b>\u5404\u6cbb\u7642\u306eSUCRA\u5024<\/b><br \/>\nSUCRA:surface under the cumulative ranking curve<\/p>\n<p><a href=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2017\/03\/sucra_0313.jpg\"><img decoding=\"async\" src=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2017\/03\/sucra_0313.jpg\" alt=\"\" width=\"60%\" class=\"aligncenter size-full wp-image-8448\" srcset=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2017\/03\/sucra_0313.jpg 719w, http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2017\/03\/sucra_0313-300x36.jpg 300w\" sizes=\"(max-width: 719px) 100vw, 719px\" \/><\/a>\n<\/td>\n<\/tr>\n<tr>\n<td style=\"border:1px dotted #000000; padding:5px; background:#ffffff;\">\n<p>SUCRA\u5024\u306e\u9806\u4f4d\u306f\u3001RTX>POCY>MTX>AZA>MMF\u3067\u3059\u3002<\/p>\n<\/table>\n<p>\n&nbsp;<\/p>\n<p><b>\u25a0\u56f3\uff14\uff0e interval plot\uff08Serious adverse event\uff09<\/b><\/p>\n<table width=\"100%\" border=\"1\" style=\"border-collapse:collapse;border:none;\">\n<tr>\n<td style=\"border:1px solid #000000; padding:5px; background:#ffffff;\">\n<a href=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2017\/03\/interval_plotadverse.jpg\"><img decoding=\"async\" src=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2017\/03\/interval_plotadverse.jpg\" alt=\"\" width=\"80%\" class=\"aligncenter size-full wp-image-8451\" srcset=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2017\/03\/interval_plotadverse.jpg 852w, http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2017\/03\/interval_plotadverse-300x144.jpg 300w, http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2017\/03\/interval_plotadverse-768x369.jpg 768w\" sizes=\"(max-width: 852px) 100vw, 852px\" \/><\/a>\n<\/td>\n<\/tr>\n<tr>\n<td style=\"border:1px dotted #000000; padding:5px; background:#ffffff;\">\n<p>\u5bdb\u89e3\u7dad\u6301\u306eserious adverse event\u306b\u95a2\u3059\u308b\u5404\u6cbb\u7642\u306e\u6bd4\u8f03\uff08\u5bfe\u7167\uff1aAZA\uff09<\/p>\n<\/td>\n<\/tr>\n<\/table>\n<p>\n&nbsp;<\/p>\n<p><b>\u25a0\u56f3\uff17\uff0e Efficacy\u3068\u5bb3\uff08tolerability\uff09\u3092\u52d8\u6848\u3057\u305f\u4e8c\u6b21\u5143\u3067\u306eCluster plot<\/b><br \/>\n\u30d7\u30ed\u30c3\u30c8\u306e\u53f3\u4e0a\u304c\u512a\u4f4d\u306e\u6cbb\u7642<\/p>\n<table width=\"100%\" summary=\"nma\" border=\"1\" style=\"border-collapse:collapse;border:none;\">\n<tr>\n<td style=\"border:1px solid #000000; padding:5px; background:#ffffff;\">\n<a href=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2017\/03\/cluster-2_0313.jpg\"><img decoding=\"async\" src=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2017\/03\/cluster-2_0313.jpg\" alt=\"\" width=\"80%\" class=\"aligncenter size-full wp-image-8452\" srcset=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2017\/03\/cluster-2_0313.jpg 839w, http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2017\/03\/cluster-2_0313-300x209.jpg 300w, http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2017\/03\/cluster-2_0313-768x535.jpg 768w\" sizes=\"(max-width: 839px) 100vw, 839px\" \/><\/a>\n<\/td>\n<\/tr>\n<tr>\n<td style=\"border:1px dotted #000000; padding:5px; background:#ffffff;\">\n<p>RTX\u306f\u6709\u52b9\u6027\u304c\u9ad8\u304f\u3001MMF\u306f\u5fcd\u5bb9\u6027\u304c\u9ad8\u3044\u3002<\/p>\n<\/td>\n<\/tr>\n<\/table>\n<p>\n&nbsp;<\/p>\n<p><b>\u25a0\u56f3\uff18\uff0e Efficacy\u3068tolerability\u306b\u3088\u308bdendrogram<\/b><\/p>\n<table>\n<tr>\n<td style=\"border:1px solid #000000; padding:5px; background:#ffffff;\">\n<a href=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2017\/03\/dendrogram2_0313.jpg\"><img decoding=\"async\" src=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2017\/03\/dendrogram2_0313.jpg\" alt=\"\" width=\"80%\" class=\"aligncenter size-full wp-image-8453\" srcset=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2017\/03\/dendrogram2_0313.jpg 823w, http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2017\/03\/dendrogram2_0313-300x216.jpg 300w, http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2017\/03\/dendrogram2_0313-768x553.jpg 768w\" sizes=\"(max-width: 823px) 100vw, 823px\" \/><\/a>\n<\/td>\n<\/tr>\n<tr>\n<td style=\"border:1px dotted #000000; padding:5px; background:#ffffff;\">\n<p>\u5bdb\u89e3\u304c\u5f97\u3089\u308c\u305f\u5f8c\u3067\u306f\u3001Do no harm\u306e\u57fa\u672c\u304b\u3089\u306f\u3001\u5bdb\u89e3\u7dad\u6301\u3068\u3057\u3066\u306f\u3001MMF, MTX\u3092\u8003\u616e\u3059\u3079\u304d\u306a\u306e\u304b\u3002<\/p>\n<\/td>\n<\/tr>\n<\/table>\n<p><\/p>\n<p>\u5bdb\u89e3\u5c0e\u5165\u6cbb\u7642\u3042\u308b\u3044\u306f\u5bdb\u89e3\u7dad\u6301\u7642\u6cd5\u306b\u95a2\u3057\u3066\u3001\u6d77\u5916\u306e\u8a3a\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3067\u306f\u3069\u3046\u306a\u3063\u3066\u3044\u308b\u306e\u304b\u3092\u8abf\u3079\u3088\u3046\u3068\u601d\u3044\u307e\u3057\u305f\u304c\u3001\u6b8b\u5ff5\u306a\u304c\u3089\u3001\u6d77\u5916\u306e\u8a3a\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3067\u306f\u3001\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u78ba\u5b9f\u6027\u8a55\u4fa1\u306fbody of evidence\u3067\u306f\u306a\u304f\u3001\u7814\u7a76\u30c7\u30b6\u30a4\u30f3\u306b\u3088\u308b\u7b49\u7d1a\u4ed8\u3051\u3067\u3057\u305f\u3002<\/p>\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>ANCA\u8a3a\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f32017\u306b\u304a\u3051\u308b\u5bdb\u89e3\u7dad\u6301\u7642\u6cd5\u306e\u52b9\u679c\u3092\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\uff08NMA\uff09\u3092\u4f7f\u3063\u305f\u8996\u70b9\u3067\u8a55\u4fa1\u3057\u3066\u307f\u307e\u3059\u3002\u63a1\u7528\u3057\u305f\u30c7\u30fc\u30bf\u306f\u3059\u3079\u3066\u3001ANCA-2017\u3067\u8a18\u8f09\u3055\u308c\u3066\u3044\u308b\u3082\u306e\u3092\u5229\u7528\u3057\u307e\u3057\u305f\u3002 \u3053\u3053\u3067\u3082\u3001ef [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[458,16],"tags":[],"_links":{"self":[{"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/posts\/8434"}],"collection":[{"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=8434"}],"version-history":[{"count":12,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/posts\/8434\/revisions"}],"predecessor-version":[{"id":8456,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/posts\/8434\/revisions\/8456"}],"wp:attachment":[{"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=8434"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=8434"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=8434"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}