{"id":9199,"date":"2019-02-23T09:58:01","date_gmt":"2019-02-23T00:58:01","guid":{"rendered":"http:\/\/aihara.la.coocan.jp\/?p=9199"},"modified":"2019-02-23T09:58:26","modified_gmt":"2019-02-23T00:58:26","slug":"%e9%96%be%e5%80%a4%e3%83%a2%e3%83%87%e3%83%ab%e3%81%ae%e5%86%8d%e6%a4%9c%e8%a8%8e","status":"publish","type":"post","link":"http:\/\/aihara.la.coocan.jp\/?p=9199","title":{"rendered":"\u95be\u5024\u30e2\u30c7\u30eb\u306e\u518d\u691c\u8a0e: \u60a3\u8005\u306e\u4fa1\u5024\u89b3"},"content":{"rendered":"

\u60a3\u8005\u306e\u4fa1\u5024\u89b3\u3084\u610f\u5411<\/b>\u3092\u8003\u616e\u3057\u305f\u884c\u52d5\u6c7a\u5b9a\u306b\u95a2\u3059\u308b\u8ad6\u6587\u3067\u3059\u3002
\nThe threshold model revisited<\/b>
\nDjulbegovic B, Hozo I, Mayrhofer T4, van den Ende J, Guyatt G.
\nJ Eval Clin Pract. 2018 Dec 21. doi: 10.1111\/jep.13091<\/a><\/p>\n

<\/p>\n

\u4f8b\u3048\u3070\u3001\u300c\u3069\u3093\u306a\u9759\u8108\u585e\u6813\u75c7\uff08VTE\uff09\u306e\u78ba\u7387\u306a\u3089\u3070\u3001\u6297\u51dd\u56fa\u7642\u6cd5\u306e\u5229\u76ca\u304c\u51fa\u8840\u3092\u4e0a\u56de\u308b\u304b\u300d\u3001\u3042\u308b\u3044\u306f\u300c\u3069\u3093\u306aVTE\u518d\u767a\u30ea\u30b9\u30af\u306a\u3089\u3070\u6297\u51dd\u56fa\u7642\u6cd5\u306e\u5229\u76ca\u304c\u51fa\u8840\u30ea\u30b9\u30af\u3092\u4e0a\u56de\u308b\u304b\u300d\u3068\u3044\u3046\uff12\u3064\u306e\u30bf\u30a4\u30d7\u306e\u7591\u554f\u306b\u5bfe\u51e6\u3059\u308b\u6c7a\u65ad\u652f\u63f4\u30e2\u30c7\u30eb\u3067\u3059\u3002<\/p>\n

\u8a08\u7b97\u306e\u8a73\u7d30\u306f\u3001\u8ad6\u6587\u3092\u53c2\u7167\u3057\u3066\u3044\u305f\u3060\u304f\u3068\u3057\u3066\u3001\u5177\u4f53\u7684\u306a\u4f8b\u3067\u8a55\u4fa1\u3057\u3066\u307f\u308b\u3068\u6b21\u306e\u3088\u3046\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n

<\/p>\n

\u8a3a\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u306e\u305f\u3081\u306eGRADE\u30b7\u30b9\u30c6\u30e03\u7248\u306ePart2\u306b\u304a\u3044\u3066\u7d39\u4ecb\u3057\u305f\u30c8\u30ea\u30d7\u30ebX\u6cbb\u7642\u306b\u304a\u3044\u3066\u3001\u30a2\u30a6\u30c8\u30ab\u30e0\uff1d\u5fc3\u7b4b\u6897\u585e\uff08MI\uff09\u306b\u95a2\u3057\u3066\u306fRR=0.892\u3001\u51fa\u8840\u7387\u306f0.01\u3067\u3057\u305f\u3002<\/p>\n

\n\n\n\n\n\n\n
\u5fc3\u7b4b\u6897\u585e(MI)<\/b><\/td>\nEvent(MI)<\/b><\/td>\ntotal<\/b><\/td>\nRate<\/b><\/td>\n<\/tr>\n
Triple x\uff08MIrX\uff09<\/b><\/td>\n394<\/b><\/td>\n1564<\/b><\/td>\n0.252<\/b><\/td>\n<\/tr>\n
Placebo (MI)<\/b><\/td>\n457<\/b><\/td>\n1618<\/b><\/td>\n0.282<\/b><\/td>\n<\/tr>\n
RR=0.892
RRR=0.108<\/td>\n<\/tr>\n
\u51fa\u8840 (Hrx)<\/b><\/td>\n10<\/b><\/td>\n1010<\/b><\/td>\n0.01<\/b><\/td>\n<\/tr>\n<\/table>\n
\n

\u6ce8\uff1a MI: myocardial infarction, MIrx: treatment related MI, Hrx: treatment related harms, RRR: relative risk reduction <\/p>\n<\/div>\n<\/div>\n

\n 
\n<\/p>\n

\n

\u25a0\u8a3a\u65ad\u304c\u78ba\u5b9f\u3067\u3042\u308b\u3053\u3068\u3092\u793a\u3059\u78ba\u7387\u3068\u30a2\u30a6\u30c8\u3068\u30ab\u30e0\u306e\u9593\u306b\u4f9d\u5b58\u6027\u304c\u3042\u308b\u5834\u5408\uff08\u3059\u306a\u308f\u3061\u3001\u521d\u56de\u30a4\u30d9\u30f3\u30c8\u306b\u3088\u3063\u3066\u3067\u304d\u305f\u518d\u767a\u7d20\u56e0\u3092\u8a3a\u65ad\u306e\u5b9a\u7fa9\u3068\u3059\u308b\uff09<\/b><\/p>\n<\/div>\n

\u25cf\u60a3\u8005\u306e\u4fa1\u5024\u89b3\u3068\u610f\u5411\u3092\u8003\u616e\u3059\u308b<\/b><\/p>\n

\"\"<\/a>
\n<\/p>\n

\u5927\u51fa\u8840\u306e\u76f8\u5bfe\u7684\u4fa1\u5024\uff08relative value of bleeding: RVB\uff09\u3092\u3001\uff11\u304b\u30890.05\uff08\u5927\u51fa\u8840\u56de\u907f\u3088\u308a\u3082\u5fc3\u7b4b\u6897\u585e\u56de\u907f\u306b20\u500d\u306e\u4fa1\u5024\uff09\u306b\u5909\u5316\u3055\u305b\u3066\u4ecb\u5165\u306e\u6709\u52b9\u6027\u3092\u8a55\u4fa1\u3059\u308b\u3068\u3001\u4ee5\u4e0b\u306e\u3088\u3046\u306b\u306a\u308b\u3002<\/p>\n

\n\"\"<\/a><\/p>\n

\u3064\u307e\u308a\u3001\u5fc3\u7b4b\u6897\u585e\u56de\u907f\u306e\u4fa1\u5024\u3092\u5927\u51fa\u8840\u56de\u907f\u306e\u305d\u308c\u306e4\u500d\uff08RV=0.25\uff09\u3068\u60f3\u5b9a\u3059\u308b\u3068\u3001\u5fc3\u7b4b\u6897\u585e\u767a\u75c7\u30ea\u30b9\u30af\uff08Mt\uff09\u304c\u9752\u7dda\u306e\u95be\u5024\u7dda\uff08X\u8ef8\uff1a\u51fa\u8840\u30ea\u30b9\u30af\uff09\u3088\u308a\u3082\u4e0a\u306b\u3042\u308b\u5834\u5408\u306b\u3001\u30c8\u30ea\u30d7\u30ebX\u6cbb\u7642\u3092\u5b9f\u65bd\u3059\u3079\u304d\u3067\u3042\u308b\u3002<\/p>\n

<\/p>\n

\n

\u25a0\u30a2\u30a6\u30c8\u30ab\u30e0\u3068\u75be\u60a3\u78ba\u7387\u304c\u72ec\u7acb\u3057\u3066\u3044\u308b\u5834\u5408\uff08\u6b7b\u4ea1\uff09<\/b><\/p>\n<\/div>\n

\u25cf\u60a3\u8005\u306e\u4fa1\u5024\u89b3\u3068\u610f\u5411\u3092\u8003\u616e\u3059\u308b<\/b><\/p>\n

\"\"<\/a>
\n<\/p>\n

\u5927\u51fa\u8840\u306e\u30a4\u30d9\u30f3\u30c8\u7387\u30920\uff5e0.05\u307e\u3067\u306b\u5909\u5316\u3055\u305b\u3066\u3001\u5927\u51fa\u8840\u306e\u6b7b\u4ea1\u306b\u5bfe\u3059\u308b\u76f8\u5bfe\u7684\u4fa1\u5024\u3092\uff11\uff08\u6b7b\u4ea1\u3068\u5927\u51fa\u8840\u304c\u540c\u7b49\u306e\u4fa1\u5024\uff09\u30010.5\uff08\u6b7b\u4ea1\u306f\u5927\u51fa\u8840\u306e2\u500d\u306e\u4fa1\u5024\uff09, 0.05\uff0820\u500d\u306e\u4fa1\u5024\uff09\u306e\u5834\u5408\u3067\u6bd4\u8f03\u3059\u308b\u3068\u4ee5\u4e0b\u306e\u3088\u3046\u306b\u306a\u308b\u3002<\/p>\n

\"\"<\/a>
\n<\/p>\n

\u6b7b\u4ea1\u304c\u51fa\u8840\u306e20\u500d\u4fa1\u5024\u304c\u3042\u308b\u3068\u3059\u308b\u3068\uff08RvB\uff1d0.05, \u9ec4\u8272\u30e9\u30a4\u30f3\uff09\u3001\u51fa\u8840\u30ea\u30b9\u30af\u304c 0.01\u306e\u5834\u5408\u306f\u3001\u6b7b\u4ea1\u306eCER 0.2\u4ee5\u4e0a\u306a\u3089\u3070\u3001\u30c8\u30ea\u30d7\u30eb\u30fcX\u6cbb\u7642\u3092\u63a8\u5968\u3059\u308b\u3002<\/p>\n

\n 
<\/p>\n","protected":false},"excerpt":{"rendered":"

\u60a3\u8005\u306e\u4fa1\u5024\u89b3\u3084\u610f\u5411\u3092\u8003\u616e\u3057\u305f\u884c\u52d5\u6c7a\u5b9a\u306b\u95a2\u3059\u308b\u8ad6\u6587\u3067\u3059\u3002 The threshold model revisited Djulbegovic B, Hozo I, Mayrhofer T4, van den Ende J, […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[464],"tags":[],"_links":{"self":[{"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/posts\/9199"}],"collection":[{"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=9199"}],"version-history":[{"count":33,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/posts\/9199\/revisions"}],"predecessor-version":[{"id":9237,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/posts\/9199\/revisions\/9237"}],"wp:attachment":[{"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=9199"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=9199"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=9199"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}