{"id":9409,"date":"2019-03-25T15:50:38","date_gmt":"2019-03-25T06:50:38","guid":{"rendered":"http:\/\/aihara.la.coocan.jp\/?p=9409"},"modified":"2019-03-25T21:09:11","modified_gmt":"2019-03-25T12:09:11","slug":"%e3%82%a2%e3%82%a6%e3%83%88%e3%82%ab%e3%83%a0%e3%83%87%e3%83%bc%e3%82%bf%e6%ac%a0%e6%90%8d%e3%81%aerob","status":"publish","type":"post","link":"http:\/\/aihara.la.coocan.jp\/?p=9409","title":{"rendered":"\u30a2\u30a6\u30c8\u30ab\u30e0\u30c7\u30fc\u30bf\u6b20\u640d\u306b\u95a2\u3059\u308bRoB\u8a55\u4fa1"},"content":{"rendered":"<p>\u7d50\u679c\u306e\u4fe1\u983c\u6027\u3092\u4f4e\u4e0b\u3055\u305b\u308b\u53c2\u52a0\u8005\u30a2\u30a6\u30c8\u30ab\u30e0\u30c7\u30fc\u30bf\u306e\u6b20\u640d\uff08missing outcome data\uff09\u306b\u95a2\u9023\u3059\u308b\u30d0\u30a4\u30a2\u30b9\u306e\u30ea\u30b9\u30af\uff08RoB\uff09\u306e\u7a0b\u5ea6\u306f\u3001\u3059\u3079\u3066\u306e\u30b7\u30b9\u30c6\u30de\u30c6\u30a3\u30c3\u30af\u30ec\u30d3\u30e5\u30fc\u306e\u91cd\u8981\u306a\u554f\u984c\u3067\u3059\u3002<br \/>\n\u305f\u3068\u3048\u3070\u3001\u9ad8\u3044RoB\u3068\u3057\u3066\u6b20\u640d\u30c7\u30fc\u30bf10%\u3068\u3044\u3046\u95be\u5024\u3092\u8a2d\u5b9a\u3057\u3001\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u306b\u304a\u3051\u308b6\u4ef6\u306e\u7814\u7a76\u306e\u3046\u3061\u30013\u4ef6\u306f\u6b20\u640d\u30c7\u30fc\u30bf\u306a\u3057\u30013\u4ef6\u306f12\uff05\u306e\u6b20\u640d\u30c7\u30fc\u30bf\u3092\u6301\u3064\u3068\u4eee\u5b9a\u3057\u307e\u3059\u3002\u3053\u306e\u3088\u3046\u306a\u5834\u5408\u3001\u3069\u306e\u3088\u3046\u306b\u3057\u3066\u3001\u30a8\u30d3\u30c7\u30f3\u30b9\u7dcf\u4f53\u306b\u308f\u305f\u3063\u3066\u3001\u53c2\u52a0\u8005\u306e\u6b20\u640d\u30c7\u30fc\u30bf\u306b\u3088\u308bRoB\u306e\u305f\u3081\u306e\u7b49\u7d1a\u30c0\u30a6\u30f3\u3092\u3059\u3079\u304d\u304b\u5426\u304b\u3092\u6c7a\u5b9a\u3059\u308b\u306e\u3067\u3057\u3087\u3046\u304b\uff1f<\/p>\n<p>\u30a2\u30a6\u30c8\u30ab\u30e0\u30c7\u30fc\u30bf\u306e\u6b20\u640d\u304c\u3042\u308b\u5834\u5408\u306eRoB\u8a55\u4fa1\u306b\u3064\u3044\u3066GRADE\u304c\u63d0\u6848\u3057\u3066\u3044\u308b\u6226\u7565\uff08imputation\uff1a\u88dc\u5b8c\u3001\u4ee3\u5165\uff09\u3092\u89e3\u8aac\u3057\u3066\u3044\u308b\u3082\u306e\u304c\u3001JCE GRADE\u30b7\u30ea\u30fc\u30ba\u306e#17\u3067\u3059\u3002<\/p>\n<div style=\"font-size: 0.8em\">\n<p><span style=\"color:#008080;\"><b>GRADE guidelines 17: assessing the risk of bias associated with missing participant outcome data in a body of evidence.<\/b> <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28529188\">J Clin Epidemiol. 2017 Jul;87:14-22<\/a><\/span><\/p>\n<\/div>\n<p>\nGRADE\u304c\u63a8\u5968\u3059\u308bimputation\u6226\u7565\u306f\u3001\u5b8c\u4e86\u8ffd\u8de1\u53c2\u52a0\u8005\u3068\u6bd4\u8f03\u3057\u305f\u6b20\u640d\u30c7\u30fc\u30bf\u53c2\u52a0\u8005\u306b\u304a\u3051\u308b\u30a2\u30a6\u30c8\u30ab\u30e0\u4e8b\u8c61\u306e\u767a\u751f\u7387\uff08relative incidence\uff09\u3092\u4f7f\u3046\u3082\u306e\u3067\u3001\u6b20\u640d\u30c7\u30fc\u30bf\u3092\u6709\u3059\u308b\u53c2\u52a0\u8005\u9593\u306e\u672a\u77e5\u306e\u30aa\u30c3\u30ba\u3068\u5229\u7528\u53ef\u80fd\u306a\u30c7\u30fc\u30bf\u3092\u6301\u3064\u53c2\u52a0\u8005\u9593\u306e\u65e2\u77e5\u306e\u30aa\u30c3\u30ba\u306e\u95a2\u4fc2\u3092\u4f7f\u3046<b>informative missingness odds ratio\uff08IMOR\uff09<\/b>\u3068\u4f3c\u305f\u3082\u306e\u3067\u3059\u3002<\/p>\n<p>\u3053\u3053\u3067\u306f\u3001missing outcome data\u306b\u5bfe\u3059\u308bGRADE\u306b\u3088\u308bRoB\u8a55\u4fa1\u306e\uff13\u3064\u306e\u4f8b\u3092\u7d39\u4ecb\u3057\u307e\u3059\u3002<\/p>\n<div style=\"font-size: 1.2em\">\n<p><span style=\"color:#008080;\">\u3000<br \/>\n<b>(1) RoB\u306e\u30b0\u30ec\u30fc\u30c9\u30c0\u30a6\u30f3\u306a\u3057<\/b><br \/><\/span><\/p>\n<\/div>\n<p>\uff08Clostridium difficile\u611f\u67d3\u3092\u4e88\u9632\u3059\u308b\u305f\u3081\u306e\u30d7\u30ed\u30d0\u30a4\u30aa\u30c6\u30a3\u30af\u30b9\uff09<br \/>\n20\u4ef6\u306e\u30e9\u30f3\u30c0\u30e0\u5316\u8a66\u9a13\u306e\u3046\u306113\u4ef6\u3067\u3001\u53c2\u52a0\u8005\u306e5\uff05\u301c45\uff05\u304cClostridium difficile\u611f\u67d3\u306b\u95a2\u3059\u308b\u30c7\u30fc\u30bf\u306e\u6b20\u640d\u304c\u3042\u3063\u305f\u3002<br \/>\n\u5bfe\u7167\u7fa4\u3067\u306f\u30a2\u30a6\u30c8\u30ab\u30e0\u30c7\u30fc\u30bf\u6b20\u640d\u8005\u3068\u8ffd\u8de1\u6210\u529f\u8005\u306e\u9593\u3067\u3001\u30a4\u30d9\u30f3\u30c8\u767a\u751f\u7387\u304c\u540c\u3058\u3067\u3042\u308b\u3068\u4eee\u5b9a\u3057\u3001\u30d7\u30ed\u30d0\u30a4\u30aa\u30c6\u30a3\u30af\u30b9\u7fa4\u3067\u306f\u3001\u30a2\u30a6\u30c8\u30ab\u30e0\u30c7\u30fc\u30bf\u6b20\u640d\u8005\u306e\u76f8\u5bfe\u767a\u75c7\u7387\uff08RI\uff09\u3092RI<sub>MPD\/FU<\/sub> 1.5, 2.0, 3.0, 5.0\u3068\u3044\u3046\u4eee\u5b9a\u3092\u7528\u3044\u3066\u8abf\u67fb\u3057\u305f\u3002\u7d50\u679c\u306f\u3001\u5404RI\u306e\u4eee\u5b9a\u306b\u5bfe\u3057\u3066\u9811\u5065\u3067\u3042\u308b\u3053\u3068\u304c\u8a3c\u660e\u3055\u308c\u3001RI=5.0\u3067\u3082\u30d7\u30ed\u30d0\u30a4\u30aa\u30c6\u30a3\u30af\u30b9\u306e\u6709\u76ca\u52b9\u679c\u306f\u5927\u304d\u304f\u7dad\u6301\u3055\u308c\u300195\uff05CI\u306f\u72ed\u3044\uff08\u76f8\u5bfe\u30ea\u30b9\u30af0.50 [0.34\u301c0.76]\uff09\uff08\u56f3\uff11\uff09\u3002<br \/>\u3057\u305f\u304c\u3063\u3066\u3001<span style=\"color:#ff0000;\">\u30c7\u30fc\u30bf\u6b20\u640d\u306b\u3088\u308bRoB\u306b\u95a2\u3057\u3066\u3001GRADE\u306e\u7b49\u7d1a\u30c0\u30a6\u30f3\u306a\u3057<\/span>\u3002<br \/>\n<br \/>\n<b>\u56f31\uff1aClostridium-difficile\u95a2\u9023\u75be\u60a3\u3092\u4e88\u9632\u3059\u308b\u305f\u3081\u306e\u30d7\u30ed\u30d0\u30a4\u30aa\u30c6\u30a3\u30af\u30b9\u306e\u611f\u5ea6\u5206\u6790<\/b><br \/>\n\u7d71\u5408\u5024\u306e\u307f\u8868\u793a\u3002<\/p>\n<div style=\"font-size: 0.8em\">\n<p>\u6ce8\uff1a\u5404\u7814\u7a76\u30c7\u30fc\u30bf\u3092\u8868\u793a\u3057\u305f\u30d5\u30a9\u30ec\u30b9\u30c8\u30d7\u30ed\u30c3\u30c8\u306f<a href=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2019\/03\/probiotics_Forest-plot.pdf\">probiotics_Forest plot<\/a>\u53c2\u7167\u3002<br \/>\n\u30d5\u30a9\u30ec\u30b9\u30c8\u30d7\u30ed\u30c3\u30c8\u306f\u3001\u81ea\u5206\u3067RevMan\u5165\u529b\u89e3\u6790\u3057\u305f\u7d50\u679c\u3067\u3059\u304c\u3001\u5b9f\u969b\u306e\u8ad6\u6587\u30c7\u30fc\u30bf\u3068\u306f\u82e5\u5e72\u6570\u5024\u304c\u7570\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u8ad6\u6587\u8457\u8005\u306eElie\u3084\u89e3\u6790\u5b9f\u52d9\u8005\u306eBradley\u306a\u3069\u306b\u554f\u3044\u5408\u308f\u305b\u307e\u3057\u305f\u304c\u3001\u30c7\u30fc\u30bf\u304c\u3059\u3067\u306b\u624b\u5143\u306b\u306a\u3044\u3068\u3044\u3046\u3053\u3068\u3067\u3057\u305f\u3002(^^; <br \/>\n\u81e8\u5e8a\u7684\u306b\u306f\u554f\u984c\u306a\u3044\u3067\u3059\u304c\u3001\u304a\u305d\u3089\u304f\u3001\u3053\u306e\u8868\u793a\u30c7\u30fc\u30bf\u304c\u6b63\u78ba\u3068\u601d\u3044\u307e\u3059\u3002<\/p>\n<\/div>\n<p>\n<a href=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2019\/03\/probiotics.jpg\"><img decoding=\"async\" loading=\"lazy\" src=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2019\/03\/probiotics.jpg\" alt=\"\" width=\"500\" height=\"266\" class=\"alignnone size-full wp-image-9422\" srcset=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2019\/03\/probiotics.jpg 1081w, http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2019\/03\/probiotics-300x160.jpg 300w, http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2019\/03\/probiotics-768x410.jpg 768w, http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2019\/03\/probiotics-1024x547.jpg 1024w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/><\/a><br \/>\n<\/p>\n<div style=\"font-size: 0.8em\">Available case analysis: Complete case analysis (excluding those with missing data) as the primary analysis.<\/p>\n<\/div>\n<p><\/p>\n<div style=\"font-size: 1.2em\">\n<p><span style=\"color:#008080;\"><br \/>\n<b>(2) RoB\u306e\u30b0\u30ec\u30fc\u30c9\u30c0\u30a6\u30f3\u3042\u308a<\/b><br \/><\/span><\/p>\n<\/div>\n<p>\uff08COPD\u306b\u304a\u3051\u308b\u30c1\u30aa\u30c8\u30ed\u30d4\u30a6\u30e0\u5bfe\u9577\u6642\u9593\u4f5c\u7528\u6027\u03b2\u523a\u6fc0\u85ac\uff09<br \/>\n4\u4ef6\u306e\u30e9\u30f3\u30c0\u30e0\u5316\u8a66\u9a13\u304b\u3089\u306a\u308b\u30b7\u30b9\u30c6\u30de\u30c6\u30a3\u30c3\u30af\u30ec\u30d3\u30e5\u30fc\u3067\u3001\u30a2\u30a6\u30c8\u30ab\u30e0\u306f\u201d\u5165\u9662\u306b\u3064\u306a\u304c\u308bCOPD\u60aa\u5316\u201d\u3067\u3042\u308b\u3002\u8457\u8005\u306f\u30aa\u30c3\u30ba\u6bd40.87[0.77\uff5e0.99]\u3092\u5831\u544a\u3057\u305f\u304c\u3001\u53c2\u52a0\u8005\u306e5\uff05\u304b\u308911\uff05\u306e\u30c7\u30fc\u30bf\u304c\u6b20\u843d\u3057\u3066\u3044\u305f\u3002\u30ec\u30d3\u30e5\u30fc\u8457\u8005\u3089\u306f\u3001\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u8cea\u3092\u8a55\u4fa1\u3059\u308b\u305f\u3081\u306bGRADE\u3092\u4f7f\u7528\u3057\u3001\u6b20\u640d\u30c7\u30fc\u30bf\u306b\u3088\u308bRoB\u306e\u7d50\u679c\u3068\u3057\u3066\u3044\u305a\u308c\u306e\u30a2\u30a6\u30c8\u30ab\u30e0\u306b\u3064\u3044\u3066\u3082\u7b49\u7d1a\u30c0\u30a6\u30f3\u3068\u3057\u306a\u304b\u3063\u305f\u3002\u5b8c\u4e86\u30b1\u30fc\u30b9\u5206\u6790\u3067\u306f\u3001OR 0.83 [0.73\u30010.94]\u3067\u3042\u3063\u305f\u3002<br \/>\n&nbsp;<br \/>\n\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u306e\u4ecb\u5165\u7fa4\u3067\u306e\u5168\u4f53\u7684\u306a\u30a4\u30d9\u30f3\u30c8\u767a\u751f\u7387\u306f16\uff05\u3067\u3042\u308a\u3001RI<sub>MPD\/FU<\/sub>\u6bd4\u304c1.5, 2.0, 3.0\u306e\u53ef\u80fd\u6027\u304c\u3042\u308b\u3068\u8003\u3048\u305f\u3002 5.0\u306eRI<sub>MPD\/FU<\/sub>\u306f\u3042\u308a\u305d\u3046\u306b\u306a\u3044\u3068\u8003\u3048\u3089\u308c\u305f\uff08\u3053\u306e\u5834\u5408\u3001\u53c2\u52a0\u8005\u306e80\uff05\u304c\u60aa\u5316\u306e\u305f\u3081\u306b\u5165\u9662\u3057\u305f\u3067\u3042\u308d\u3046\uff09\u3002<br \/>\n\u7d71\u8a08\u7684\u6709\u610f\u6027\u306f\u3001RI<sub>MPD\/FU<\/sub>2.0\u306e\u4eee\u5b9a\u3067\u306f\u5883\u754c\u3067\u3042\u308a\uff08OR\u30010.89 [0.79\u301c1.00]\uff09\u3001RI<sub>MPD\/FU<\/sub>3.0\u3067\u306f\u6d88\u5931\u3057\u305f\uff08\u56f32\uff09\u3002\u3057\u305f\u304c\u3063\u3066\u3001<span style=\"color:#ff0000;\">\u6b20\u640d\u30c7\u30fc\u30bf\u306b\u3088\u308bRoB\u306e\u305f\u3081\u306b\u7b49\u7d1a\u30c0\u30a6\u30f3\u3042\u308a<\/span>\u3002<br \/>\n<br \/>\n<b>\u56f32\uff1a\u5b89\u5b9a\u3057\u305fCOPD\u306b\u304a\u3051\u308b\u30c1\u30aa\u30c8\u30ed\u30d4\u30a6\u30e0\u5bfe\u9577\u6642\u9593\u4f5c\u7528\u6027\u03b2\u523a\u6fc0\u85ac\u306e\u611f\u5ea6\u5206\u6790<\/b><br \/>\n<a href=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2019\/03\/copd_forest.png\"><img decoding=\"async\" loading=\"lazy\" src=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2019\/03\/copd_forest.png\" alt=\"\" width=\"500\" height=\"400\" class=\"alignnone size-full wp-image-9433\" \/><\/a><br \/>\n<\/p>\n<div style=\"font-size: 1.2em\">\n<p><span style=\"color:#008080;\"><br \/>\n<b>(3) RoB\u306e\u30b0\u30ec\u30fc\u30c9\u30c0\u30a6\u30f3\u3042\u308a<\/b><br \/><\/span><\/p>\n<\/div>\n<p>\uff08COPD\u306b\u304a\u3051\u308b\u904b\u52d5\u8a13\u7df4\u4e2d\u306e\u975e\u4fb5\u8972\u7684\u63db\u6c17\uff08Non-invasive ventilation\uff1aNIV\uff09\uff09<br \/>\n2\u4ef6\u306e\u30e9\u30f3\u30c0\u30e0\u5316\u8a66\u9a13\u304b\u3089\u306a\u308b\u30b7\u30b9\u30c6\u30de\u30c6\u30a3\u30c3\u30af\u30ec\u30d3\u30e5\u30fc\u3067\u3001\u30a2\u30a6\u30c8\u30ab\u30e0\u306f\u201d\u81ea\u8ee2\u8eca\u30a8\u30eb\u30b4\u30e1\u30fc\u30bf\u306e\u8010\u4e45\u6642\u9593\u306e\u5909\u5316\u201d\u3067\u3042\u308b\u3002\u5b8c\u4e86\u30b1\u30fc\u30b9\u5206\u6790\u3067\u306f\u3001\u5e73\u5747\u5dee58.68 [3.76\u301c113.59]\u3067\u3042\u3063\u305f\u304c\u30012\u4ef6\u306e\u7814\u7a76\u306b\u304a\u3051\u308b\u53c2\u52a0\u8005\u306e21.6\uff05\u306834.5\uff05\u306e\u30c7\u30fc\u30bf\u304c\u6b20\u843d\u3057\u3066\u3044\u305f\u3002\u30ec\u30d3\u30e5\u30fc\u8457\u8005\u3089\u306f\u3001GRADE\u3092\u4f7f\u7528\u3057\u3066\u3001\u6b20\u640d\u30c7\u30fc\u30bf\u306b\u3088\u308b\u30d0\u30a4\u30a2\u30b9\u306e\u30ea\u30b9\u30af\u3092\u4f4e\u3044\u3068\u8a55\u4fa1\u3057\u305f\u3002<\/p>\n<p>GRADE\u306emissing data\u306b\u95a2\u3059\u308bRoB\u8a55\u4fa1\u6307\u91dd\u306b\u3057\u305f\u304c\u3063\u3066\u3001\u6b20\u640d\u30c7\u30fc\u30bf\u306b\u95a2\u3059\u308b\u8aac\u5f97\u3067\u304d\u308b\u4eee\u5b9a\u3092\u4f7f\u3063\u3066\u3001RoB\u3092\u518d\u8a55\u4fa1\u3057\u305f\u3002\u7d50\u679c\u306e\u9811\u5065\u6027\u306f\u7b2c1\u6226\u7565\uff08\u542b\u307e\u308c\u3066\u3044\u308b\u5404\u8a66\u9a13\u306e\u4e21\u7fa4\u306e\u6b20\u843d\u30c7\u30fc\u30bf\u306e\u5e73\u5747\u30b9\u30b3\u30a2\u306f\u3001\u691c\u8a0e\u4e2d\u306e\u8a66\u9a13\u306e\u5bfe\u7167\u7fa4\u306e\u5e73\u5747\u30b9\u30b3\u30a2\u3068\u7b49\u3057\u3044\u3068\u4eee\u5b9a\uff09\u304b\u3089\u5931\u308f\u308c\u305f\uff08\u5e73\u5747\u5dee42.94 [-4.79 \u301c90.68]\uff09\uff08\u56f33\uff09\u3002<br \/>\n\u3057\u305f\u304c\u3063\u3066\u3001<span style=\"color:#ff0000;\">\u6b20\u640d\u30c7\u30fc\u30bf\u306b\u3088\u308bRoB\u306e\u305f\u3081\u306b\u7b49\u7d1a\u30c0\u30a6\u30f3\u3042\u308a<\/span>\u3002<br \/>\n<br \/>\n<b>\u56f33\uff1aCOPD\u306b\u304a\u3051\u308b\u904b\u52d5\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u4e2d\u306eNIV\u306e\u611f\u5ea6\u5206\u6790<\/b><br \/>\n<a href=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2019\/03\/niv_forest.png\"><img decoding=\"async\" loading=\"lazy\" src=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2019\/03\/niv_forest.png\" alt=\"\" width=\"500\" height=\"370\" class=\"alignnone size-full wp-image-9449\" srcset=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2019\/03\/niv_forest.png 642w, http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2019\/03\/niv_forest-300x221.png 300w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/><\/a><br \/>\n<br \/>\n&nbsp;<br \/>\n\u3053\u308c\u3089\u306e\u5185\u5bb9\u306b\u95a2\u3057\u3066\u306f\u3001GRADE3\u7248\u306ep49\uff5ep52\u300c\u6b20\u640d\u30c7\u30fc\u30bf\u306b\u95a2\u3059\u308b\u88dc\u5b8c\u89e3\u6790\u3068\u611f\u5ea6\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u300d\u3092\u53c2\u7167\u304f\u3060\u3055\u3044\u3002<br \/>\n\u4e00\u9023\u306e\u88dc\u5b8c\uff08\u4ee3\u5165\uff09\u6226\u7565\u306b\u304a\u3044\u3066\u306f\u3001\u201dplausible worst case\u201d\u306e\u4eee\u5b9a\u304c\u91cd\u8981\u3067\u3059\u3002<\/p>\n<div style=\"font-size: 0.8em\">\n<p>\u6ce8\uff1a<a href=\"http:\/\/www.grade-jpn.com\/grade3e_cover.html\"><b>GRADE3e\u66f8\u7c4d<\/b><\/a>\u306ep52\u3067\u8a18\u8f09\u3057\u305f\uff15\u3064\u306e\u30c7\u30fc\u30bf\u30bd\u30fc\u30b9\u306b\u95a2\u3057\u3066\u3001\u66f8\u7c4d\u3067\u306f\u201d\u756a\u53f7\uff081\uff5e5\uff09\u201d\u3068\u5217\u8a18\u3057\u3066\u3044\u307e\u3059\u304c\u3001\u201dA\uff5eE\u201d\u306e\u9593\u9055\u3044\u3067\u3057\u305f\uff08\u539f\u8457\u8ad6\u6587\u3001\u307e\u305f\u306f\u51fa\u7248\u793e\u306e\u6b63\u8aa4\u8868\u3092\u53c2\u7167\uff09\u3002<\/p>\n<\/div>\n<p><a href=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2019\/03\/p52.jpg\"><img decoding=\"async\" loading=\"lazy\" src=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2019\/03\/p52.jpg\" alt=\"\" width=\"500\" height=\"76\" class=\"alignnone size-full wp-image-9500\" srcset=\"http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2019\/03\/p52-300x47.jpg 300w, http:\/\/aihara.la.coocan.jp\/blog\/wp-content\/uploads\/2019\/03\/p52-768x119.jpg 768w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/><\/a><br \/>\n<br \/>\n&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u7d50\u679c\u306e\u4fe1\u983c\u6027\u3092\u4f4e\u4e0b\u3055\u305b\u308b\u53c2\u52a0\u8005\u30a2\u30a6\u30c8\u30ab\u30e0\u30c7\u30fc\u30bf\u306e\u6b20\u640d\uff08missing outcome data\uff09\u306b\u95a2\u9023\u3059\u308b\u30d0\u30a4\u30a2\u30b9\u306e\u30ea\u30b9\u30af\uff08RoB\uff09\u306e\u7a0b\u5ea6\u306f\u3001\u3059\u3079\u3066\u306e\u30b7\u30b9\u30c6\u30de\u30c6\u30a3\u30c3\u30af\u30ec\u30d3\u30e5\u30fc\u306e\u91cd\u8981\u306a\u554f\u984c\u3067\u3059\u3002 \u305f\u3068\u3048\u3070\u3001\u9ad8\u3044RoB\u3068\u3057\u3066 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[5,63],"tags":[],"_links":{"self":[{"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/posts\/9409"}],"collection":[{"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=9409"}],"version-history":[{"count":63,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/posts\/9409\/revisions"}],"predecessor-version":[{"id":9506,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=\/wp\/v2\/posts\/9409\/revisions\/9506"}],"wp:attachment":[{"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=9409"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=9409"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/aihara.la.coocan.jp\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=9409"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}