Archive for: 󈥬月 2022’

連続アウトカムのサンプルサイズ

2022年12月10日 Posted by aihara

2021年7月にFBで紹介しましたが、サンプルサイズの計算にミスがあり、訂正論文が発表されています。

Corrigendum to GRADE guidelines 6. Rating the quality of evidence-imprecision. J Clin Epidemiol 2011;64:1283–1293
https://www.jclinepi.com/article/S0895-4356(21)00137-2/fulltext

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The authors regret, in the above-mentioned article, we discovered an error related to standards for adequate precision
in systematic reviews of continuous variables. The relevant paragraph reads as follows: “Because it may give false reassurance, we hesitate to offer a rule-of-thumb threshold for the absolute number of patients required for adequate precision for continuous variables. For example, using the usual standards of α (0.05) and β (0.20), and an effect size of 0.2 standard deviations, representing a small effect, requires a total samples size of approximately 400 (200 per group) – a sample size that may not be sufficient to ensure prognostic balance.” .
The sample size stated is incorrect: the correct number is 800 (400 per group).
The authors would like to apologise for any inconvenience caused. The authors are grateful to Mark Chatfield for pointing out this error.

 

 

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